Genetic toxicology and cancer risk assessment
By: edited by Wai Nang Choy.
Contributors: Choy, Wai Nang, 1946-
Publisher: Marcel Dekker
Published: 2001
Place of publication: New York
Language: eng
Number of pages: 390
Subjects: Carcinogenicity testing.; Genetic toxicology.; Mutagenicity testing.; Cancer -- Risk factors.; Cancérogénicité.; Toxicologie génétique.; Mutagénicité.; Cancer -- Facteurs de risque.; Mutagenicity Tests -- methods.; Neoplasms -- etiology.; Risk Assessment.
Notes: Includes bibliographical references and index.
Table of contents: title: Human cancer genetics; title: Genetic toxicity for predicting carcinogenicity; title: Genotoxic and nongenotoxic mechanisms of carcinogenesis; title: Structure-activity relationship (SAR) and its role in cancer risk assessment; title: Regulatory genetic toxicology tests; title: Complementary genetic toxicology assays; title: The mouse lymphoma assay (MLA) using the microwell method; title: The in vivo micronucleus assay; title: ICH guidances on genotoxicity and carcinogenicity: scientific background and regulatory practice; title: New OECD genetic toxicology guidelines and interpretation of results; title: Dose-response relationships in chemical carcinogenesis and cancer risk assessment; title: Molecular epidemiology and biomarkers; title: Quantitative cancer risk assessment of nongenotoxic carcinogens; title: Risk assessment of genotoxic carcinogens; title: Biologically based cancer risk assessment models.