Cancer Immunotherapy at the Crossroads
Subtitle: How Tumors Evade Immunity and What Can Be Done (Current Clinical Oncology)
Contributors: James H. Finke (Editor); Ronald M. Bukowski (Editor)
Edition: 1 edition
Publisher: Humana Press
Published: November 24, 2003
Language: eng
Format: Hardcover
Number of pages: 408
ISBN-13: 9781588291837
Subjects: Neoplasms; Immunotherapy; Medical; Medical / Nursing; therapy; Nursing - Oncology & Cancer; Oncology; Medical / Oncology; Immunological aspects; Cancer
First sentence: The rationale behind the use of T-cell-based immunotherapy for the treatment of solid tumors relies on the convincing evidence in animal model systems (1) and more recently in patients with cutaneous melanoma (2,3) that major histocompatibility complex (MHC) class I antigen-restricted, tumor-associated antigen (TAA)-specific cytotoxic T lymphocytes (CTLs) control tumor growth.