Inflammatory diseases of the central nervous system
By: [edited by] Trevor Kilpatrick, Richard M. Ransohoff, Steven Wesselingh
Series: Cambridge medicine; Cambridge medicine
Publisher: Cambridge University Press
Published: 2010
Place of publication: Cambridge; New York
Language: eng
Number of pages: 271
ISBN-13: 9780521888745
Description: "Interactions between the immune and nervous systems are involved in many disease processes. Modulation of inflammation can provide an important opportunity to enhance regeneration within the central nervous system. This authoritative book defines the key cellular players in mounting an inflammatory response and highlights critical factors in the target organ that influence the nature of that response and its capacity either to damage or protect the brain. Several key clinical areas are highlighted - particularly autoimmune diseases of the nervous system including multiple sclerosis, as well as microbiological and traumatic challenges; the book therefore provides both a summary of the basic science background as well as practical, clinical-friendly guidelines to management. The book will be of interest to a wide range of physicians, including neurologists, neurosurgeons, neurorehabilitationists, infectious disease physicians, and clinical neuroscientists, as well as neuroscientists and immunologists"--Provided by publisher.
Notes: Includes bibliographical references and index.
Table of contents: title: Interactions between the immune and nervous systems; title: Effectors and determinants of the innate and adaptive immune responses / Edgar Meinl & Hartmut Wekerle; title: Microglia: protective and pathogenic mediators / Bevyn Jarrott & Karina Apricơ; title: The role of dendritic cells in neuro-inflammation / Heather Donaghy, Edwina J. Wright & Anthony L. Cunningham; title: Negotiating the brain barriers: access of immune cells and pathogens into the CNS / Britta Engelghardt; title: Autoimmunity; title: Immune effector heterogeneity in multiple sclerosis and related CNS inflammatory demyelinating disorders Shaunu F. Roemer & Claudia F. Lucchinetti; title: Multiple sclerosis : neuro-immune cross-talk in acute and progressive stages of the disease / Martin Kerschensteiner & Reinhard Hohlfeld; title: CD8+ T Cell-mediated autoimmune diseases in the CNS / Lisa Walter & Matthew L. Albert; title: Acute disseminated encephalomyelitis: determinants and manifestations / Eppie M. Yiu & Andrew J. Kornberg; title: Primary angiitis of the CNS and its mimics / Tina Chadha, George F. Duna & Leonard H. Calabrese; title: Microbiological and traumatic challenges to the CNS; title: Acute viral encephalitis : role of the immune system in viral clearance from the CNS and in the generation of pathology / David N. Irani & Natalie Prow; title: Chronic HIV infection of the CNS: role of the immune system in virological control and the generation of pathology / Carolyn F. Orr & Bruce J. Brew; title: Brain inflammation during bacterial meningitis / Trine H. Mogensen & Lars Østergaard; title: Parasitic infections of the brain: malaria and beyond / Stephen J. Rogerson & Danny A. Milner, Jr; title: Role of the inflammatory process in traumatic brain damage / Cristina Morganti-Kossmann ... [et al.]; title: Therapy; title: HIV-associated neurocognitive disorders: clinical features and therapeutic challenges / Nicoline Schiess & Justin C. McArthur; title: Role of immunomodulation in management of infections of the CNS / Miles H. Beaman; title: Neuroinflammation: an emerging therapeutic target in neurological disease / Joseph M. Antony & Christopher Power.