Semaphorins
Subtitle: receptor and intracellular signaling mechanisms
By: edited by R. Jeroen Pasterkamp.
Contributors: Pasterkamp, R. Jeroen.
Publisher: Springer Science+Business Media; Landes Bioscience
Published: 2007
Place of publication: New York, N.Y; Austin, Tex
Language: eng
Number of pages: 147
ISBN-13: 9780387709550
Subjects: Semaphorins; Cell receptors; Cellular signal transduction; Intercellular Signaling Peptides and Proteins -- physiology; Semaphorins -- physiology; Receptors, Cell Surface -- physiology
Description: The book summarizes our progress in understanding the receptor and intracellular signaling mechanisms utilized by a family of proteins called the semaphorins. Originally these protein were identified as "axon guidance cues" important for the formation of nerve tracts but now it is realized that semaphorins subserve several distinct functions in a multitude of organ systems. The purpose of this book is to summarize our knowledge and make it available as a useful and comprehensive tool for the scientific community. This book will both be interesting for people working in the field as well as colleagues that work in other fields of science and would like to learn more about semaphorins and associated signaling mechanisms. All the latest techniques and results are summarized in this book which covers the entire semaphorin field from neurosciences to cardiovascular research and beyond. The strength of this book is that it gives a very comprehensive overview of all our knowledge of.
Table of contents: title: The CRMP family of proteins and their role in Sema3A signaling / Eric F. Schmidt and Stephen M. Strittmatter; title: GTPases in semaphorin signaling / Andreas W. Puschel; title: Intracellular kinases in semaphorin signaling / Aminul Ahmed and Britta J. Eickholt; title: Mical flavoprotein monooxygenases : structure, function, and role in semaphorin signaling / Sharon M. Kolk and R. Jeroen Pasterkamp; title: Signaling of secreted semaphorins in growth cone steering / Sangwoo Shim and Guo-li Ming; title: Modulation of semaphorin signaling by IG superfamily cell adhesion molecules / Ahmad Bechara ... [et al.]; title: Proteoglycans as modulators of axon guidance cue function / Joris de Wit and Joost Verhaagen; title: Semaphorin signals in cell adhesion and cell migration : functional role and molecular mechanisms / Andrea Casazza, Pietro Fazzari, and Luca Tamagnone.