Metabolomics Strategies for Discovery of Biologically Active or Novel Metabolites
Contributors: Saghatelian, Alan; Liu, David R.; Kahne, Daniel
Published: 2012
Language: eng
Description: Along with genes and proteins, metabolites play important roles in sustaining life. There remains much to be learned about the in vivo roles of metabolites. Metabolomics is a comparative tool to study global metabolite levels in samples under various conditions. This dissertation describes the development and application of metabolomics strategies for discovery of biologically active or novel metabolites with priori knowledge about genes, proteins, or phenotypes.
Notes: Keywords: liquid chromatography-mass spectrometry, metabolites, metabolomics.

Thesis Ph.D. Harvard University 2012