Cancer as a metabolic disease
Subtitle: on the origin, management, and prevention of cancer
By: by Thomas N. Seyfried
Publisher: John Wiley & Sons
Published: 2012
Place of publication: Hoboken, N.J
Language: eng
Number of pages: 421
ISBN-13: 9780470584927
Subjects: Neoplasms; Diet therapy; Energy Metabolism; Mitochondria; Metabolism; Ketogenic Diet
Description: The book addresses controversies related to the origins of cancer and provides solutions to cancer management and prevention. It expands upon Otto Warburg's well-known theory that all cancer is a disease of energy metabolism. However, Warburg did not link his theory to the "hallmarks of cancer" and thus his theory was discredited. This book aims to provide evidence, through case studies, that cancer is primarily a metabolic disease requring metabolic solutions for its management and prevention. Support for this position is derived from critical assessment of current cancer theories. Brain cancer case studies are presented as a proof of principle for metabolic solutions to disease management, but similarities are drawn to other types of cancer, including breast and colon, due to the same cellular mutations that they demonstrate.
Notes: Includes bibliographical references and index.
Table of contents: title: Images of cancer; title: Confusion surrounds the origin of cancer; title: Cancer models; title: Energetics of normal cells and cancer cells; title: Respiratory dysfunction in cancer cells; title: The Warburg dispute; title: Is respiration normal in most cancer cells?; title: Is mitochondrial glutamine fermentation the missing link in the metabolic theory of cancer?; title: Genes, respiration, viruses, and cancer; title: Respiratory injury, the retrograde response, and the origin of cancer; title: Mitochondria: the ultimate tumor suppressor; title: Linking abnormalities in growth control, telomerase activity, apoptosis, and angiogenesis to mitochondrial dysfunction; title: Metastasis; title: Mitochondrial respiratory dysfunction and the extrachromosomal origin of cancer; title: Nothing in cancer biology makes sense except in the light of evolution; title: Cancer treatment strategies; title: Metabolic management of cancer; title: Implementation of metabolic therapies for cancer management; title: Cancer prevention; title: Case studies and personal experiences in using the ketogenic diet for cancer management.