DNA-damage-induced apoptosis in stem and cancer cells
Contributors: Lahav, Galit; Daley, George Q.; Gaudet, Suzanne; Rossi, Derrick J.
Published: 2014
Language: eng
Description: This work comprises analyses of cell fate decision-making in response to DNA damage. DNA damage is a ubiquitous threat to genomic stability, and depending on the type and extent of the damage, can lead to widespread changes in cell function as well as cell death. How apoptosis, or programmed cell death, is triggered in damaged cells was studied in different cell types for different types of damage.
Notes: Thesis Ph.D. Harvard University 2014