Advances in Asymmetric Synthesis, Volume 3 (Advances in Asymmetric Synthesis)
Publisher: JAI Press
Published: February 18, 1999
Language: eng
Format: Hardcover
Number of pages: 380
ISBN-13: 9780762301065
Subjects: Organic chemistry; Organic Synthesis; Science; Science/Mathematics; Chemistry - Organic; General; Cognition; Intellect; Reference-General; Science / Chemistry / General; Science / Chemistry / Organic; Chemistry - General
First sentence: Since the presence of a 1-methyl substituent has been found to enhance the chemical and metabolic stability of synthetic carbapenem antibiotics (e.g. 1), a number of stereoselective syntheses of the key 1-methyl intermediate 2 have been reported.