Mass spectrometry in drug metabolism and pharmacokinetics
By: edited by Ragu Ramanathan.
Contributors: Ramanathan, Ragu.
Publisher: John Wiley & Sons
Published: 2008
Place of publication: Hoboken, N.J
Language: eng
ISBN-13: 9780471751588
Subjects: Drugs -- Metabolism -- Research -- Methodology; Drugs -- Design; Mass spectrometry; Pharmacokinetcs -- Research -- Methodology; Pharmaceutical Preparations -- metabolism; Drug Design; Drug Evaluation, Preclinical -- methods; Mass Spectrometry -- methods; Pharmacokinetics
Notes: Includes bibliographical references and index.
Table of contents: title: The evolving role of mass spectrometry in drug metabolism and pharmacokinetics / Dil Ramanathan and Richard M. LeLacheur; title: Quantitative bioanalysis in drug discovery and development : principles and applications / Ayman El-Kattan, Chris Holliman, and Lucinda H. Cohen; title: Triple quadrupole and hybrid QQQ/LIT mass spectrometers in metabolite analysis / Elliott Jones; title: Applications of quadrupole-time-of-flight mass spectrometer in reactive metabolite screening / José-Castro Perez; title: Changing role of FTMS for drug metabolism applications / Petia A. Shipkova, Jonathan L. Josephs, and Mark Sanders; title: High resolution LC-MS based mass defect filter approach : basic concept and application in metabolite detection / Haiying Zhang ... [et al.]; title: Applications of high sensitive mass spectrometry and radioactivity detection techniques in drug metabolism studies / Wing Wah Lam ... [et al.]; title: LC-MS methods with hydrogen/deuterium exchange for identification of hydroxylamine, n-oxide, and hydroxylated analogs of desloratadine / Natalia A. Penner ... [et al.]; title: On-line electrochemical/LC-MS techniques for profiling and characterizing metabolites and degradants / Paul H. Gamache ... [et al.]; title: Turbulent flow LC-MS : applications for accelerating pharmacokinetic profiling and metabolite identification / Joseph L. Herman and Joseph M. Di Bussolo; title: Desorption ionization techniques for quantitative analysis of drug molecules / Jason S. Gobey, John Janiszewski, Mark J. Cole; title: MALDI imaging mass spectrometry for direct tissue analysis of pharmaceuticals / Yunsheng Hsieh, Jiwen Chen, Walter A. Korfmacher.