Classification and measurement of speed and amplitude impairments in patients with Parkinson's disease
Subtitle: a pilot study.
Published: 2005
Language: eng
Number of pages: 114
Description: Slowness of movement ("bradykinesia") is the most important deficit in Parkinson's disease (PD). Current clinical rating of bradykinesia in PD does not separate the dimensions of slowness and amplitude reduction. We categorized patterns of movement in PD patients on a biaxial classification of speed and amplitude using an electromagnetic tracking device (Polhemus) seeking to determine whether these categories may differentially contribute to motor impairment and disability. Motor impairment was worst in patients with very impaired amplitude and best in patients with normal amplitude. Categories of speed impairment did not show a similar relationship. The Schwab & England disability scale decreased with higher severity levels of the amplitude category but not of speed. Agreement (unweighted kappa) between clinician and Polhemus-derived speed-amplitude classification were moderate for speed and amplitude classifications. Our observations suggest that amplitude and speed impairments might behave differentially in PD and may deserve consideration in a biaxial classification system.
Notes: Source: Masters Abstracts International, Volume: 44-02, page: 0867.

Thesis (M.Sc.)--University of Toronto, 2005.

Electronic version licensed for access by U. of T. users.

GERSTEIN MICROTEXT copy on microfiche (2 microfiches).