Polycystic Kidney Disease
Publisher: Codon Publications
Published: 2015 Nov
Place of publication: Brisbane, Australia
Language: eng
Format: Hardcover
Number of pages: 488
ISBN-13: 9780994438102
Description: Polycystic kidney disease (PKD) is characterized by the presence of fluid-filled cysts in the kidneys. It is the fourth most common cause of chronic renal insufficiency or end-stage kidney disease. This book focuses on the basic and clinical aspects of the burgeoning PKD research under three sections. Section 1 provides a comprehensive guide to the diagnosis, management and treatment of PKD. Section 2 covers most of the fundamental molecular and cellular mechanisms underlying PKD, and how this knowledge is contributing to the development of potential novel therapeutic agents. Finally, section 3 focuses on extra-renal or secondary complications of PKD.

Contributors: 48; Chapters: 20; Figures: 42; Tables: 12; Pages: 488
Notes: Copyright © 2015 Codon Publications.
Published under Creative Commons Attribution 4.0 International (CC BY 4.0). Users are allowed to share (copy and redistribute the material in any medium or format) and adapt (remix, transform, and build upon the material for any purpose, even commercially), as long as the authors and the publisher are explicitly identified and properly acknowledged as the original source.
Table of contents: title: Foreword; title: Preface; title: Contributors; title: Section I. Diagnosis, Management and Treatment; title: 1. Differential Diagnosis of Autosomal Dominant Polycystic Kidney Disease; title: 2. Childhood Polycystic Kidney Disease; title: 3. Treatment and Management of Autosomal Dominant Polycystic Kidney Disease; title: 4. Diagnosis and Treatment Modalities of Symptomatic Polycystic Kidney Disease; title: 5. Blood Pressure Control for Polycystic Kidney Disease; title: 6. Clinical Trials in Autosomal Dominant Polycystic Kidney Disease; title: Section II. Molecular Mechanisms; title: 7. Polycystins and Molecular Basis of Autosomal Dominant Polycystic Kidney Disease; title: 8. The Role of Calcium and Cyclic AMP in PKD; title: 9. Apoptosis in Polycystic Kidney Disease: From Pathogenesis to Treatment; title: 10. c-Myc Signalling in the Genetic Mechanism of Polycystic Kidney Disease; title: 11. The Role of G-protein Coupled Receptor Proteolytic Site (GPS) Cleavage in Polycystin-1 Biogenesis, Trafficking and Function; title: 12. Epigenetics in ADPKD: Understanding Mechanisms and Discovering Treatment; title: 13. MicroRNAs and Polycystic Kidney Disease; title: 14. Role of Inflammation in Polycystic Kidney Disease; title: 15. Autosomal Dominant Polycystic Kidney Disease Induced by Ciliary Defects; title: 16. Implications of Dysfunction of Mechanosensory Cilia in Polycystic Kidney Disease; title: Section III. Extra-renal Manifestations; title: 17. The Liver and Polycystic Kidney Disease; title: 18. Seminal Vesicles in Autosomal Dominant Polycystic Kidney Disease; title: 19. Craniofacial Development and Growth in Polycystic Kidney Disease; title: 20. Rapidly Progressive Glomerulonephritis in Autosomal Dominant Polycystic Kidney Disease