Malaria rapid diagnostic test performance
Subtitle: results of WHO product testing of malaria RDTs : round 1 (2008)
Contributors: Special Programme for Research and Training in Tropical Diseases; Foundation for Innovative New Diagnostics; Centers for Disease Control (U.S.)
Publisher: World Health Organization on behalf of the Special Programme for Research and Training in Tropical Diseases
Published: 2009
Place of publication: Geneva
Language: eng
Number of pages: 98
ISBN-13: 9789241598071
Subjects: Statistics; Malaria; Rapid methods (Microbiology); Testing; Microbiology; Parasite antigens; Laboratory Diagnosis; Diagnosis; Evaluation; Plasmodium
Description: The largest-ever independent, laboratory-based evaluation of rapid diagnostic tests (RDTs) for malaria has shown that some tests perform exceptionally well in tropical temperatures and can detect even low parasite densities in blood samples, while other tests were only able to detect malaria at high parasite densities.The evaluation was co-sponsored by the WHO Regional Office for the Western Pacific (WPRO), TDR, and the Foundation for Innovative New Diagnostics (FIND). Testing was performed at the US Centers for Disease Control and Prevention (CDC). Forty-one commercially available RDTs went through a blinded laboratory evaluation. The findings will serve as a tool aiding countries and donor agencies to make more informed choices about test purchases and use, from among the dozens of diagnostics commercially available.The performance evaluation will also inform procurement and prioritization for diagnostic test entry into the WHO Prequalification of Diagnostics Program and WHO Procurement Schemes.--Publisher's description.
Notes: "Foundation for Innovative New Diagnostics, CDC".

Includes bibliographical references (p. 43).

Also available online.
Table of contents: title: Executive summary; title: Background; title: Objectives; title: Materials and methods; title: Data management; title: Quality assurance; title: Ethical considerations; title: Data analysis; title: Laboratory versus field-based malaria RDT evaluations; title: Results; title: Heat stability; title: Ease of use description; title: Discussion of key findings; title: Additional measures to ensure quality and utility of RDT testing; title: Conclusions.