Biopharmaceutics modeling and simulations
Subtitle: theory, practice, methods, and applications
By: Kiyohiko Sugano
Publisher: John Wiley & Sons
Published: 2013
Place of publication: Hoboken, N.J
Language: eng
ISBN-13: 9781118028681
Subjects: Biopharmaceutics; Theoretical Models; Computer Simulation; Methods; Drug Compounding
Notes: Includes bibliographical references and index.
Table of contents: title: Introduction; title: Theoretical framework I : solubility; title: Theoretical framework II : dissolution; title: Theoretical framework III : biological membrane permeation; title: Theoretical framework IV : gastrointestinal transit models and integration; title: Physiology of gastrointestinal tract and other administration sites in humans and animals; title: Drug parameters; title: Validation of mechanistic models; title: Bioequivalence and biopharmaceutical classification system; title: Dose and particle size dependency; title: Enabling formulations; title: Food effect; title: Biopharmaceutical modeling for miscellaneous cases; title: Intestinal transporters; title: Strategy in drug discovery and development; title: Epistemology of biopharmaceutical modeling and good simulation practice.