Drug discovery research
Subtitle: new frontiers in the post-genomic era
By: [edited by] Ziwei Huang.
Contributors: Huang, Ziwei, 1965-
Publisher: John Wiley & Sons
Published: 2007
Place of publication: Hoboken, N.J
Language: eng
Number of pages: 566
ISBN-13: 9780471672005
Subjects: Drugs -- Design; Biopharmaceuticals; Pharmaceutical chemistry; Drug Design; Biopharmaceutics -- methods; Chemistry, Pharmaceutical -- methods; Genomics -- methods
Description: xix, 521 p., [16] p. of plates : 25 cm
Notes: Includes bibliographical references and index.
Table of contents: title: Molecular docking and structure-based design / P. Therese Lang ... [et al.]; title: Recent advances in drug discovery research using structure-based virtual screening techniques : examples of success for diverse protein targets / Sutapa Ghosh ... [et al.]; title: Virtual screening in drug discovery / Malcolm J. McGregor, Zhaowen Luo, Xuliang Jiang; title: Computer-aided drug design / Grace Shiahuy Chen and Ji-Wang Chern; title: Focused library design based on hit and target structures : method and application in drug discovery / Weiliang Zhu ... [et al.]; title: Beyond natural products : synthetic analogs of bryostatin 1 / Paul A. Wender ... [et al.]; title: The promises and pitfalls of small molecule inhibition of poly(ADP-ribose) glycohydrolase (PARG) / Amanda C. Nottbohm and Paul J. Hergenrother; title: Cyclic ADP-ribose analogues with minimal structure : synthesis and calcium-release activity / Lihe Zhang and Andreas H. Guse; title: Evaluation of neuroimmunophilin ligands / Junhai Xiao, Aihua Nie, Song Li; title: Chiral drugs and the associated asymmetric synthesis / Jiange Zhang and Guoqiang Lin; title: Alpha-helix mimetics in drug discovery / Hang Yin, Gui-In Lee, Andrew D. Hamilton; title: Basic and translational research of chemokine ligands and receptors and development of novel therapeutics / Won-Tak Choi ... [et al.]; title: Research progress in protein post-translational modification / Jia Hu, Yanting Guo, Yanmei Li; title: Controlled release of antibiotics encapsulated in nanoporous sol-gel materials with tunable pore parameters / Houping Yin, Laura Zheng, Yen Wei; title: Retinoic acid and arsenic trioxide treatment in acute promyelocytic leukemia-a model of oncoprotein targeted therapy / Jian-Hua Tong, Sai-Juan Chen, Zhu Chen.; title: 2-chlorodeoxyadenosine (cladribine) : rational development of a novel chemotherapeutic agent / Howard B. Cottam and Dennis A. Carson; title: Apoptosis-based drug discovery for cancer / John C. Reed ... [et al.]; title: Mechanism-based development of memantine as a therapeutic agent in treating Alzheimer's disease and other neurologic disorders : low-affinity, uncompetitive antagonism with fast off-rate / Huei-Sheng Vincent Chen and Stuart A. Lipton; title: Bridging bench to clinic : roles of animal models for post-genomics drug discovery on metabolic diseases / Chi-Wai Wong and Ling Chen; title: Stem cell research and applications for human therapies / Prithi Rajan ... [et al.].