Biology of Depression 
Subtitle: From Novel Insights to Therapeutic Strategies (2 vol. set)
Contributors: Julio Licinio (Editor); Ma-Li Wong (Editor)
Edition: 1 edition
Publisher: Wiley-VCH
Published: May 6, 2005
Language: eng
Format: Hardcover
Number of pages: 1095
ISBN-13: 9783527307852
Subjects: Chemistry; Other Branches of Medicine; Science; Science/Mathematics; Psychiatry - General; Medical / Psychiatry; Science / Genetics; Life Sciences - Genetics & Genomics
Description: The first major reference to cover the clinical aspects of this common and complex disorder of unknown cause. Readers will also learn about current understanding of the psychosocial, environmental, biological, and genetic aspects of depression. The authors are internationally recognized experts from leading academic and industrial environments, and they present the features, advantages, and limitations of animal models while reviewing candidate biological systems and genetic approaches. In addition, the book covers the important topic of the medical consequences of depression, as clinicians and investigators increasingly appreciate how it negatively impacts on cardiovascular function and bone mineral density. Finally, a separate section is devoted to the biochemical and molecular basis for existing treatments, along with strategies for the use of genomic tools to discover new targets for antidepressants and to predict therapeutic outcomes.