Ebola and Marburg viruses
Subtitle: molecular and cellular biology
By: edited by Hans-Dieter Klenk and Heinz Feldmann.
Contributors: Feldmann, Heinz.; Klenk, H.-D. 1938-
Publisher: Horizon Bioscience
Published: 2004
Place of publication: Wymondham, Norfolk, U.K
Language: eng
Number of pages: 369
Subjects: Marburg virus.; Marburg virus disease.; Ebola virus disease.; Molecular virology.
Description: The Ebola and Marburg viruses are a pair of filoviruses that are among the most lethal hemorrhagic viruses on the planet. The authors present a review of past and current research into these pathogens, including 12 papers addressing the structure of the viral proteins; genomic replication; molecular mechanisms of entry; pathogenesis in nonhuman primates, guinea pigs, and mice; virus modulation of innate immunity; and cellular and molecular mechanisms of Ebola pathogenicity and related approaches to vaccine development.
Notes: Includes bibliographical references and index.