Untranslated gene regions and other non-coding elements
Subtitle: regulation of eukaryotic gene expression
By: Lucy W. Barrett, Sue Fletcher, Steve D. Wilton
Contributors: Fletcher, Sue (Neuromuscular research professor), author; Wilton, Steve D., author
Series: Springerbriefs in biochemistry and molecular biology; SpringerBriefs in biochemistry and molecular biology
Publisher: Springer
Published: 2013
Place of publication: Basel; New York
Language: eng
Number of pages: 56
ISBN-13: 9783034806787; 9783034806794
Subjects: Non-coding RNA; Untranslated Regions; Genetics; Eukaryotic Cells; Gene Expression Regulation; Regulator Genes; SCIENCE / Life Sciences / Molecular Biology
Description: There is now compelling evidence that the complexity of higher organisms correlates with the relative amount of non-coding RNA rather than the number of protein-coding genes. Previously dismissed as ""junk DNA"", it is the non-coding regions of the genome that are responsible for regulation, facilitating complex temporal and spatial gene expression through the combinatorial effect of numerous mechanisms and interactions working together to fine-tune gene expression. The major regions involved in regulation of a particular gene are the 5' and 3' untranslated regions and introns. --
Notes: Includes bibliographical references.
Table of contents: title: Introduction --; title: Promoter --; title: 5' Untranslated region --; title: Intronic region --; title: 3' intronic region --; title: Non-coding RNAs --; title: Conclusion