Language representation in children with medically intractable epilepsy
Subtitle: findings from extraoperative stimulation mapping, intracarotid sodium-amobarbital procedure, and functional magnetic resonance imaging.
Published: 2004
Language: eng
Number of pages: 103
Description: Language representation was investigated in 25 children and adolescents with medically intractable epilepsy using intracarotid sodium amobarbital procedure (IAP), functional magnetic resonance imaging (fMRI), and extraoperative stimulation mapping (ESM), prior to surgical intervention. Findings across all procedures indicated elevated atypical (right or bilateral) language representation in this population. ESM identified left-hemisphere language sites outside classical language areas, suggesting ipsilateral reorganization. Possible relationships between language representation and several demographic and seizure-related variables were explored. ESM, IAP, and fMRI yielded largely consistent findings, although the measures were not simply redundant; each technique provides distinct data and unique opportunities for language study. It was concluded that the multiple language mapping procedures worked best together---data provided by one measure could benefit later investigations.
Notes: Adviser:  Mary Lou Smith.

Thesis (M.A.)--University of Toronto, 2004.

Electronic version licensed for access by U. of T. users.

Source: Masters Abstracts International, Volume: 42-06, page: 2345.

MICR copy on microfiche (2 microfiches).