Endothelial Regulation of Vascular Tone
Publisher: Informa Healthcare
Published: November 27, 1991
Language: eng
Format: Hardcover
Number of pages: 416
ISBN-13: 9780824785789
Subjects: Cardiovascular medicine; Vascular resistance; Medical / Nursing; Cardiovascular Diseases; Human Cardiovascular System; Vascular endothelium; Medical; Physiology; Nitric oxide; Cardiology; Pathology; Medical / Pathology; Endothelins; Endothelium-Derived Relaxing F
First sentence: Following the first description by Furchgott and Zawadzki (1) of an essential role for the endothelium in mediating the relaxations to acetylcholine in mammalian arteries, the question was posed whether or not the response represented a pharmacological curiosity (because of the ubiquitous enzyme acetylcholinesterase, acetylcholine is not a substrate usually considered a circulating hormone).