Single-cell mutation monitoring systems
Subtitle: methodologies and applications
By: edited by Aftab A. Ansari and Frederick J. de Serres.
Contributors: Ansari, Aftab A.; De Serres, Frederick J.
Series: Topics in chemical mutagenesis ;; v. 2
Publisher: Plenum Press
Published: 1984
Place of publication: New York
Language: eng
Number of pages: 289
Subjects: Mutagenicity testing.
Notes: Includes bibliographical references and index.
Table of contents: title: ch. 1. Somatic-cell mutation monitoring system based on human hemoglobin mutants / George Stamatoyannopoulos ... [et al.]; title: ch. 2. Use of fluorescence-activated cell sorter for screening mutant cells / William L. Bigbee and Elbert W. Branscomb; title: ch. 3. Development of a plaque assay for the detection of red blood cells carrying abnormal or mutant hemoglobins / Masroor A. Baig and Aftab A. Ansari; title: ch. 4. Direct assay by autoradiography for 6-thioguanine-resistant lymphocytes in human peripheral blood / Richard J. Albertini, Philip C. Kelleher, and David L. Sylwester; title: ch. 5. Application of antibodies to 5-Bromodeoxyuridine for the detection of cells or rare genotype / Howard G. Gratzner; title: ch. 6. Cytogenetic abnormalities as an indicator of mutagenic exposure / R. Julian Preston; title: ch. 7. Sister chromatid exchange analysis in lymphocytes / James W. Allen ... [et al.]; title: ch. 8. Unscheduled DNA synthesis as an indicator of genotoxic exposure / Ann D. Mitchell and Jon C. Mirsalis; title: ch. 9. The micronucleus test as an indicator of mutagenic exposure / Robert R. Racine and Bernhard E. Matter; title: ch. 10. The identification of somatic mutations in immunoglobulin expression and structure / Donald J. Zack and Matthew D. Scharff; title: ch. 11. Detection of chemically induced Y-chromosomal nondisjunction in human spermatozoa / Marvin S. Legator and Robert W. Kapp, Jr.