Almonds, glycemic excursions, oxidative stress and risk factors for coronary heart disease.
Published: 2006
Language: eng
Number of pages: 170
ISBN-13: 9780494213414
Description: Postprandial hyperglycemia is associated with an increased risk of diabetes and heart disease. Almonds may reduce postprandial glycemia since they contain protein, fat and antioxidants. In healthy subjects, almonds, consumed with white bread, at doses of 30g, 60g, and 90g, reduced glycemic excursions in a dose-dependant manner (r=-0.46, n=38, P=0.004). Furthermore, the 60g almond and bread meal reduced protein oxidative damage as loss of protein thiols (P=0.021), compared to other meals including the bread meal, and the potato and rice meals with added protein and fat. Postprandial glucose and insulin response areas were inversely correlated to the change in protein thiols for the four meals (n=15, P=0.001; and n=15, P=0.008 respectively), providing evidence that the magnitude of the glycemic excursion is a determinant of oxidative damage. Reduced postprandial glycemia, plus endogenous antioxidants, may be part of the reason why almond consumption is associated with reduced CHD risk.
Notes: Source: Masters Abstracts International, Volume: 45-03, page: 1465.

Thesis (M.Sc.)--University of Toronto, 2006.

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