Non-target effects of live vaccines
Subtitle: Langen, Germany, November 3-5, 1993 : proceedings of a workshop / organized by the Organisation for Economic Co-operation and Development (OCDE), Group of National Experts on Safety in Biotechnology, Working Group III, Safety Assessment, Micro-organisms Subgroup.
Contributors: Organisation for Economic Co-operation and Development. Group of National Experts on Safety and Biotechnology. Working Group III, Safety Assessment, Micro-organisms Subgroup.
Series: Developments in biological standardization -- vol. 84.; Developments in biological standardization -- v. 84.
Publisher: Karger
Published: 1995
Place of publication: Basel; New York
Language: eng
Number of pages: 291
Subjects: Viral vaccines -- Environmental aspects -- Congresses.; Bacterial vaccines -- Environmental aspects -- Congresses.; Viral vaccines -- Congresses.; Bacterial vaccines -- Congresses.
Description: Live vaccines have long been recognized as being better able to stimulate protective immune responses than inactivated vaccine preparations. There has been renewed interest in their development because of the introduction of recombinant DNA technology and increasing knowledge about bacterial and viral pathogenicity. This volume deals with the efficacy and safety of both viral and bacterial live vaccines with an emphasis of non-target effects in other individuals or species. The authoritative reviews provide detailed information on a wide range of vaccines for many different diseases and describe strategies for combatting non-target effects. Live vaccines with a history of field use are reviewed, as are newer vaccines undergoing development or trial. Vectored bacterial and viral vaccines for human and animal use are also considered. Providing balanced discussion of how non-target effects can be avoided or minimized, this volume is important reading for both scientists and regulatory authorities concerned with the development and use of live vaccines.
Notes: Includes bibliographical references and index.

Summary in French.