The pattern of angiogenesis and osteogenesis in peri-implant healing compartments as a function of titanium implant surface modifications.
Published: 2006
Language: eng
Number of pages: 116
ISBN-13: 9780494210284
Description: Implant surface microtopography has been seen to influence bone-to-implant contact and the strength of that interface. Though angiogenesis is necessary for osteogenesis, little attention has been paid to this interrelationship. To further analyze these processes a BaSO4 radio-opaque vascular perfusion compound was developed to allow for simultaneous, non-destructive, 3D, qualitative, and quantitative analysis of bone and vasculature using MicroCT. Early time points of 2, 3, 4, 6 and 15 days were analyzed with a combination of BaSO4 vascular perfusion, MicroCT, BSEI, and/or block histology around dual surface gap healing implants in the rat  femur. The BaSO 4 compound developed was found to have sufficient radio-density and perfusability to allow for simultaneous MicroCT and BSEI analysis of both bone and vasculature and block histology, of 6 and 15 day samples, demonstrated that implant surface texture does influence peri-implant osteogenesis, but at a level undetectable by the MicroCT and BSEI methods used.
Notes: Source: Masters Abstracts International, Volume: 45-03, page: 1559.

Thesis (M.A.Sc.)--University of Toronto, 2006.

Electronic version licensed for access by U. of T. users.

ROBARTS MICROTEXT copy on microfiche.