Guidelines for surveillance of drug resistance in tuberculosis
Contributors: Gemert, Wayne van; Glaziou, Philippe; Weyer, Karin; Zignol, Matteo; WHO/IUATLD Global Project on Anti-tuberculosis Drug Resistance Surveillance; World Health Organization
Edition: 4th ed.
Publisher: World Health Organization
Published: 2009
Place of publication: Geneva
Language: eng
Format: [electronic resource]
Number of pages: 83
ISBN-13: 9789241598675
Subjects: Data Collection; Antitubercular Agents; Drug Resistance; Pharmacology; Sentinel Surveillance; Standards; Epidemiology; Tuberculosis, Multidrug-Resistant; Guideline; Methods
Description: "This fourth edition of World Health Organization (WHO) Guidelines for surveillance of drug resistance in tuberculosis is an updated version of earlier editions published in 1994, 1997 and 2003. These guidelines incorporate the 2007 WHO Interim recommendations for the surveillance of drug resistance in tuberculosis, as well as the conclusions of an Expert Committee Meeting on Anti-Tuberculosis Drug Resistance Surveys held in Geneva in September 2008. In addition, the guidelines take into account recent advancements in laboratory diagnostics and subsequent WHO guidance, including the 2008 WHO Policy guidance on drug-susceptibility testing (DST) of second-line anti-tuberculosis drugs and the 2008 WHO Policy Statement, Molecular line probe assays for rapid screening of patients at risk of multidrug-resistant tuberculosis. Furthermore, these updated guidelines incorporate the wealth of experience gained from 15 years of the Global Project on Anti-Tuberculosis Drug Resistance Surveillance (hereinafter, referred to as the Global Project), a project initiated by WHO and the International Union Against Tuberculosis and Lung Disease (The Union)."--P. ix.
Notes: "WHO/HTM/TB/2009.422."

"This updated edition of the guidelines was written by: Wayne van Gemert, Matteo Zignol, Dennis Falzon, Philippe Glaziou, Karin Weyer."--P. vii.

Includes bibliographical references (p. 51-54).

Mode of access: World Wide Web as an Acrobat .pdf file (1.22 MB, 98 p.).

System requirements: Adobe Acrobat Reader.
Table of contents: title: Part I. Principles of anti-tuberculosis drug resistance surveillance in the Global Project; title: 1. Mechanisms of surveillance that produce data representative of a geographically-defined population; title: 2. Standardized stratification of results by patient categories; title: 3. Quality-assured laboratory methods for determining resistance to first- and second-line drugs; title: 4. Ethical considerations; title: Part II. Conducting a survey; title: 5. Survey planning; title: 6. Survey logistics; title: 7. Survey data management and analysis; title: References; title: Annex 1a. First-line anti-tuberculosis drug resistance results; title: Annex 1b. Second-line anti-tuberculosis drug resistance results; title: Annex 1c. Multidrug resistance stratified by age groups and sex; title: Annex 1d. Multidrug resistance stratified by patient hiv status; title: Annex 2. Supranational reference laboratory list; title: Annex 3a. Example of a proficiency testing results form (first-line drugs); title: Annex 3b. Example of a proficiency testing results form (second-line drugs); title: Annex 4a. Example of a proficiency testing analysis sheet (first-line drugs); title: Annex 4b. Example of a proficiency testing analysis sheet (second-line drugs); title: Annex 5a. Example of a rechecking analysis sheet (first-line drugs); title: Annex 5b. Example of a rechecking analysis sheet (second-line drugs); title: Annex 6. Drug resistance survey protocol checklist; title: Annex 7. Weighted cluster sampling; title: Annex 8. Survey budget template; title: Annex 9. Example of a clinical information form; title: Annex 10. Safe shipment of infectious material; title: Annex 11. Sample size for rechecking TB strains.