THERAPEUTIC COMPLIANCE AMONG PATIENTS ON LITHIUM THERAPY: EFFECTS OF MONITORING AND FEEDBACK.
Contributors: St. Louis University.
Published: 1988
Number of pages: 342
Subjects: Health Sciences, Mental Health.; Health Sciences, Nursing.; Health Sciences, Education.; Social Work.; Psychology, Clinical.
Description: This study employed a two-group randomized experimental design to assess the effects of monitoring and feedback on the medication compliance of patients on lithium therapy. Monitoring was performed with an electronic medication monitor which recorded the time and day that pills were removed from the container. The relationship between patients' health beliefs and medication compliance was also assessed.

Over a 13-month period, 93 psychiatric outpatients were enrolled. Experimental group patients used the medication monitor for two to four months after which they received detailed feedback about their monitoring results. At this time, the control group also received feedback regarding serum lithium level results. Each patient participated in three interviews which assessed their health beliefs. Compliance was measured using serum lithium level, prescription refills, appointment-keeping, and self-report. In addition, the monitor provided detailed compliance data for the experimental group.

Compliance was better in the monitored group as measured by appointment-keeping and prescription refills using McNemar's Chi-squared Test. After feedback, compliance in the two groups was not significantly different. The decline in compliance (from 83.2% to 76.0%) as measured by the monitor was statistically significant.

There were no changes in health beliefs as a result of the monitoring and feedback interventions. Using logistic regression, two of the eight health belief scales measured at the intake interview predicted compliance at the end of the study. Patients who considered themselves more susceptible to illness and patients with increased side effects were more likely to be compliant.

Health services utilization was measured for both groups during the course of the study; no differences were found. Measures of psychological status revealed that monitored patients had higher levels of anxiety, depression and somatic complaints at the end of the study.
Notes: Source: Dissertation Abstracts International, Volume: 49-07, Section: B, page: 2564.

Thesis (PH.D.)--SAINT LOUIS UNIVERSITY, 1988.

School code: 0193.