Drug development perspectives
Subtitle: considerations, challenges, and strategies
By: Nuggehally R. Srinivas
Publisher: HNB
Published: 2010
Place of publication: New York
Language: eng
Number of pages: 328
ISBN-13: 9780966428698
Subjects: Drugs; Research; Drug development
Notes: Includes bibliographical references and index.
Table of contents: title: Bioanalytical considerations in present-day drug development: case study of bioanalysis of halofantrine with an update on its clinical pharmacology, metabolism, transport, and distribution attributes; title: Allometry as a tool in drug development: case studies, perspectives, and general consideration; title: Cytochrome P450 2B6: stereoselective metabolism and bioassays for select substrates : drug development and clinical and therapeutic challenges; title: Development, regulatory, and practical considerations in clinical pharmacology: the use of simulations to study the pharmokinetics of orbifloxacin in rabbits; title: Clinical pharmacology of primary metabolites that exhibit genetic polymorphic disposition: case studies of pactimibe, rupatadine, and rabeprazole.