Synthetic Studies of the Yunnaneic Acids
By: Daniel Griffith
Publisher: [publisher not identified]
Published: 2013
Place of publication: [New York, N.Y.?]
Language: eng
Description: The total syntheses of yunnaneic acid C, yunnaneic acid D, and rufescenolide are described. The highly substituted bicyclic cores of these molecules were synthesized in a single step via a oxidative dearomatization/Diels-Alder cascade sequence from simple precursors. Dimerization studies towards yunnaneic acid A and yunnaneic acid B are also described, which resulted in the synthesis of several novel, non-natural structures.
Notes: Department: Chemistry.

Thesis advisor: Scott A. Snyder.

Thesis (Ph.D.)--Columbia University, 2013.