Somitogenesis
By: edited by Miguel Maroto, Neil V. Whittock.
Contributors: Maroto, Miguel.; Whittock, Neil V.
Series: Advances in experimental medicine and biology -- v. 638
Publisher: Springer Science+Business Media; Landes Bioscience
Published: 2008
Place of publication: New York, N.Y; Austin, Tex
Language: eng
ISBN-13: 9780387096056
Subjects: Somite; Somites -- physiology; Morphogenesis -- physiology
Description: We visualise developmental biology as the study of progressive changes that occur within cells, tissues and organisms themselves during their life span. A good example of a field of developmental biology in which this concept is encapsulated is that of somitogenesis. The somite was identified as the primordial unit underlying the segmented organisation of vertebrates more than two centuries ago. The spectacular discoveries and achievements in molecular biology in the last fifty years have created a gene-based revolution in both the sorts of questions as well as the approaches one can use in developmental biology today. Largely as a result of this, during the 20th and 21st centuries this simple structure, the somite, has been the focus of a deluge of papers addressing multiple aspects of somite formation and patterning both at the cellular and molecular level.
Notes: Includes bibliographical references and index.
Table of contents: title: Formation and differentiation of avian somite derivatives / Bodo Christ and Martin Scaal; title: Avian somitogenesis : translating time and space into pattern / Beate Brand-Saberi, Stefan Rudloff, and Anton J. Gamel; title: Genetic analysis of somite formation in laboratory fish models / Christoph Winkler and Harun Elmasri; title: Old wares and new : five decades of investigation of somitogenesis in Xenopus laevis / Duncan B. Sparrow; title: Role of delta "like" in mammalian somitogenesis and vertebral column formation / Gavin Chapman and Sally L. Dunwoodie; title: Mesp-family genes are required for segmental patterning and segmental border formation / Yumiko Saga and Yu Takahashi; title: BHLH proteins and their role in somitogenesis / Miguel Maroto ... [et al.]; title: Mouse mutations disrupting somitogenesis and vertebral patterning / Kenro Kusumi, William Sewell, and Megan L. O'Brien; title: Defective somitogenesis and abnormal vertebral segmentation in man / Peter D. Turnpenny.