mTor
Subtitle: methods and protocols
By: edited by Thomas Weichhart
Series: Methods in molecular biology -- 821; Springer protocols; Methods in molecular biology (Clifton, N.J.) -- v. 821.; Springer protocols
Publisher: Humana Press
Published: 2012
Place of publication: New York
Language: eng
Number of pages: 464
ISBN-13: 9781617794292; 9781617794308
Subjects: Rapamycin; Laboratory manuals
Notes: Includes bibliographical reference and index.
Table of contents: title: Mammalian target of rapamycin : a signaling kinase for every aspect of cellular life / Thomas Weichhart; title: Biochemical and pharmacological inhibition of mTOR by rapamycin and an ATP-competitive mTOR inhibitor / Ker Yu and Lourdes Toral-Barza; title: Evaluation of the nutrient-sensing mTOR pathway / Sungki Hong, Aristotle M. Mannan, and Ken Inoki; title: mTor activity under hypoxia / Douangsone D. Vadysirisack and Leif W. Ellisen; title: Isolation of the mTOR complexes by affinity purification / Dos D. Sarbassov ... [et al.]; title: An in vitro assay for the kinase activity of mTOR complex 2 / Jingxiang Huang; title: Overexpression or downregulation of mTOR in mammalian cells / Mahmoud Khalil and Ivan Gout; title: Detection of cytoplasmic and nuclear functions of mTOR by fractionation / Margit Rosner and Markus Hengstschläger; title: Evaluation of rapamycin-induced cell death / Lorenzo Galluzzi ... [et al.]; title: Evaluation of mTOR-regulated mRNA translation / Valentina Iadevaia ... [et al.]; title: A genome-wide RNAi screen for polypeptides that alter rpS6 phosphorylation / Angela Papageorgiou and Joseph Avruch; title: Immunohistochemical analysis of mTOR activity in tissues / Jinhee Kim ... [et al.]; title: Assessing cell size and cell cycle regulation in cells with altered TOR activity / Megan Cully and Julian Downward; title: Quantitative visualization of autophagy induction by mTOR inhibitors / Beat Nyfeler ... [et al.]; title: The in vivo evaluation of active-site TOR inhibitors in models of BCR-ABL+ leukemia / Matthew R. Janes and David A. Fruman; title: Inducible raptor and rictor knockout mouse embryonic fibroblasts / Nadine Cybulski, Vittoria Zinzalla, and Michael N. Hall; title: Expanding human T regulatory cells with the mTOR-inhibitor rapamycin / Manuela Battaglia, Angela Stabilini, and Eleonora Tresoldi; title: Rapamycin-induced enhancement of vaccine efficacy in mice / Chinnaswamy Jagannath and Pearl Bakhru; title: Utilizing a retroviral RNAi system to investigate in vivo mTOR functions in T cells / Koichi Araki and Bogumila T. Konieczny; title: Exploring functional in vivo consequences of the selective genetic ablation of mTOR signaling in T helper lymphocytes / Greg M. Delgoffe and Jonathan D. Powell; title: Evaluating the therapeutic potential of mTOR inhibitors using mouse genetics / Huawei Li, Jennifer L. Cotton, and David A. Guertin; title: Inhibition of PI3K-Akt-mTOR signaling in glioblastoma by mTORC1/2 inhibitors / Qi-Wen Fan and William A. Weiss; title: Assessing the function of mTOR in human embryonic stem cells / Jiaxi Zhou, Dong Li, and Fei Wang; title: Video-EEG monitoring methods for characterizing rodent models of tuberous sclerosis and epilepsy / Nicholas R. Rensing, Dongjun Guo, and Michael Wong; title: A genetic model to dissect the role of TSC-mTORC1 in neuronal cultures / Duyu Nie and Mustafa Sahin; title: Tissue-specific ablation of TSC1 in pancreatic beta-cells / Hiroyuki Mori and Kun-Liang Guan; title: A mouse model of diet-induced obesity and insulin resistance / Chao-Yung Wang and James K. Liao; title: Rapamycin as immunosuppressant in murine transplantation model / Louis-Marie Charbonnier and Alain Le Moine; title: Development of ATP-competitive mTOR inhibitors / Qingsong Liu ... [et al.]