Antisense technology in the central nervous system
By: edited by Ron A. Leslie, J. Hunter, H. Robertson
Contributors: Leslie, Ronald A; Hunter, Jackie, 1956-; Robertson, Harold A
Publisher: Oxford University Press
Published: 1999
Place of publication: New York
Language: eng
Number of pages: 250
Subjects: Neurogenetics; Antisense nucleic acids; Genetic regulation
Notes: Includes bibliographical references and index
Table of contents: title: Antisense oligonucleotide regulation of gene expression in the CNS: an overview / R.A. Leslie, A.J. Hunter, and H.A. Robertson; title: Antisense knockdown in the CNS: optimizing the strategy / Siew Peng Ho and Paul R. Hartig; title: The design of appropriate control experiments to ensure specificity in antisense oligonucleotide function / Wolfgang Brysch; title: Modulation of gene expression in the CNS as a tool in behavioral pharmacology / Wolfgang Sommer and Markus Heilig; title: Behavioral and neuroendocrine effects of antisense targeting in the rat / R. Landgraf; title: Electrophysiological and behavioral effects of dopamine receptor knockdown in the brain / Simranjit Kaur, Ian Creese, and James M. Tepper; title: Antisense mapping: exploring the functional significance of alternative splicing / Gavril W. Pasternak; title: Medicinal chemistry of antisense oligonucleotides / Sudhir Agrawal and Ekambar R. Kandimalla; title: Retinal neuronal development in the trkõB antisense knockdowns / Dennis W. Rickman; title: Pluronic gel as a means of antisense delivery / David L. Becker, Jun Sheng Lin, and Colin R. Green; title: Delivery of antisense by viral vectors for prolonged antisense effects in vivo /  M. Ian Phillips, Xiaoping Tang, and Dagmara Mohuczy; title: Regulation of genre expression in the CNS by natural antisense RNAs / Paul R. Murphy, Rai Knee, and Audrey W. Li; title: Aptamers: another use for oligonucleotides / Richard C. Cohen; title: Ribozymes: oligonucleotides with enzymatic activity have potential as regulators of gene expression in the CNS / Leonidas A. Phylactou, Marc B. Lee, and Matthew J. A. Wood; title: Antisense gene knockdown technology in the nematode Caenorhabditis elegans: applications to cholinergic synaptic transmission / Emmanuel Culetto and David B. Sattelle