Suppression and regulation of immune responses
Subtitle: methods and protocols
By: edited by Maria Cristina Cuturi and Ignacio Anegon
Series: Springer protocols; Methods in molecular biology -- 677; Springer protocols; Methods in molecular biology (Clifton, N.J.) -- v. 677.
Publisher: Humana Press
Published: 2011
Place of publication: New York
Language: eng
Number of pages: 473
ISBN-13: 9781607618683
Subjects: Laboratory manuals; Regulation; Immune response; Immunosuppression
Description: Over the past several years, a high diversity of regulatory cells and suppressive molecules has taken centre stage in the field of immunoregulation. In Suppression and Regulation of Immune Responses: Methods and Protocols, expert researchers highlight recent advances in the identification, characterization, and generation of regulatory cells not only of the T cell lineage but also of other origins such as B, NK, myeloid, and dendritic cells, as well as the role of several suppressive molecules in immunoregulation. Particular emphasis is placed on the characterization of the molecular mechanisms and the therapeutic applications of regulatory cells and molecules in human diseases. Written as a volume in the highly successful Methods in Molecular Biology series, this work provides the kind of detailed description and implementation advice that is crucial for getting optimal results. Comprehensive and cutting-edge, Suppression and Regulation of Immune Responses: Methods and Protocols serves as a key reference for scientists seeking a way toward greater control over the enormous power of the complex and vital immune system.
Notes: Includes bibliographical references and index.
Table of contents: title: Natural and induced T CD4+CD25+FOXP3+ regulatory T cells / Lucienne Chatenoud; title: Polyclonal expansion of human CD4⁺CD25⁺ regulatory T cells / Petra Hoffmann, Ruediger Eder, and Matthias Edinger; title: Methods for in vitro generation of human type 1 regulatory T cells / Silvia Gregori, Maria Grazia Roncarolo, and Rosa Bacchetta; title: Ex vivo generation of regulatory T cells : characterization and therapeutic evaluation in a model of chronic colitis / Fridrik Karlsson ... [et al.]; title: Phenotypic and functional characterization of CD8⁺ T regulatory cells / Séverine Ménoret ... [et al.]; title: Regulatory CD4⁻ CD8⁻ double negative T cells / Edward Y. Kim, Stephen C. Juvet, and Li Zhang; title: Identifying regulatory B cells (B10 cells) that produce IL-10 in mice / Takashi Matsushita and Thomas F. Tedder; title: DCs in immune tolerance in steady-state conditions / Tomohiro Fukaya ... [et al.]; title: Plasmacytoid dendritic cells in tolerance / Eric Gehrie ... [et al.]; title: In vitro-generated DC with tolerogenic functions : perspectives for in vivo cellular therapy / Cees van Kooten and Kyra A. Gelderman; title: Preparation of mouse bone marrow-derived dendritic cells with immunoregulatory properties / Mercedes Segovia, Maria Cristina Cuturi, and Marcelo Hill; title: Myeloid-derived suppressor cells : characterization and expansion in models of endotoxemia and transplantation / Nicolas Van Rompaey and Alain Le Moine; title: Human regulatory macrophages / James A. Hutchinson ... [et al.]; title: NKT and tolerance / Julien Diana ... [et al.]; title: Antiinflammatory and immunosuppressive functions of mast cells / Janet Kalesnikoff and Stephen J. Galli; title: A mesenchymal stem cell potency assay / Joy Jiao ... [et al.]; title: In vitro analyses of the immunosuppressive properties of neural stem/progenitor cells using anti-CD3/CD28-activated T cells / Virginie Bonnamain, Isabelle Neveu, and Philippe Naveilhan; title: Immunoregulatory properties of heme oxygenase-1 / Philippe Blancou ... [et al.]; title: Indoleamine 2,3-dioxygenase and regulatory function : tryptophan starvation and beyond / Ciriana Orabona and Ursula Grohmann; title: Regulatory T cell enrichment by IFN-[gamma] conditioning / Gang Feng, Kathryn J. Wood, and Andrew Bushell; title: Transforming growth factor-beta : recent advances on its role in immune tolerance / Pierre-Yves Mantel and Carsten B. Schmidt-Weber; title: Induction of tolerogenic dendritic cells by NF-[kappa]B blockade and Fc[gamma] receptor modulation / Leandro J. Carreño, Claudia A. Riedel, and Alexis M. Kalergis; title: Fine-tuning antitumor responses through the control of galectin-glycan interactions : an overview / Mariana Salatino and Gabriel A. Rabinovich; title: Regulation of lymphocytes by nitric oxide / Christian Bogdan; title: Pregnancy : tolerance and suppression of immune responses / Anne Leber ... [et al.]; title: Organ transplantation : modulation of T-cell activation pathways initiated by cell surface receptors to suppress graft rejection / Kathleen Weatherly and Michel Y. Braun; title: Immunosuppressive mechanisms during viral infectious diseases / Ghanashyam Sarikonda and Matthias G. von Herrath; title: Ocular immune privilege sites / Sharmila Masli and Jose L. Vega; title: Immunoprivileged sites : the testis / Monica Fijak, Sudhanshu Bhushan, and Andreas Meinhardt.