The effect of cholesterol esterase on fluoride release and biostability of compomers:  An in vitro study.
Published: 2006
Language: eng
Number of pages: 150
ISBN-13: 9780494211038
Description: Sample pellets of Dyract-AP, F2000 [compomers] and Z-250 [composite-resin] were prepared and incubated in either PBS or PBS with cholesterol-este rase [CE] for periods of 8, 16 and 24 days.Compomers are widely used in Pediatric Dentistry due to their handling characteristics and fluoride-release capability. Their degradation and fluoride-release in the presence of esterase-activity similar to human saliva is unknown.Methacylic-acid production was detected in all samples in both incubation medias. Bis-hydroxy-propox-yphenyl-propane was detected in Dyract-AP and Z-250 in higher amounts in the presence of CE. TCB resin from Dyract-AP was identified in higher concentrations in CE-incubated samples. Glyceryl dimethacrylate was identified in F2000 samples incubated with-and-without CE. Fluoride-release was increased in CE-incubated samples. The increased degradation from compomers could be attributed to their hydrophilicity, and may indicate an increased rate of their intra-oral breakdown. Fluoride-release in the presence of esterase may contribute to a clinical effect of reduced-rate of recurrent-caries.
Notes: Source: Masters Abstracts International, Volume: 45-03, page: 1443.

Thesis (M.Sc.)--University of Toronto, 2006.

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