Glycogen synthase kinase 3 (GSK-3) and its inhibitors
Subtitle: drug discovery and development
By: edited by Ana Martinez, Ana Castro, Miguel Medina
Contributors: Wiley online library
Series: Wiley series in drug discovery and development
Publisher: Wiley-Interscience
Published: 2006
Place of publication: Hoboken, N.J
Language: eng
Format: [electronic resource] :
ISBN-13: 9780470052174
Subjects: Protein Kinase Inhibitors; Antagonists & inhibitors; Glycogen Synthase Kinase 3; Therapeutic use; Physiology; Glycogen synthase kinase-3; Inhibitors
Notes: Includes bibliographical references and index.

Description based on print version record.
Table of contents: title: Glycogen synthase kinase 3: an introductory synopsis; title: Glycogen synthase kinase-3[beta] (GSK-3[beta]) a key signaling enzyme: a developmental neurobiological perspective; title: Role of GSK-3/Shaggy in neuronal cell biology; title: The crystal structures of glycogen synthase kinase 3; title: Kinase-kinase and site-site interactions in the phosphorylation of tau by GSK-3; title: GSK-3, a key player in Alzheimer's disease; title: Glycogen synthase kinase 3 : a target for novel mood disorder treatments; title: GSK-3 and stem cells; title: Glycogen synthase kinase 3 : role in neurodegeneration and neuroprotection.; title: Protein kinase assays for drug discovery; title: Animal models with modified expression of GSK-3 for the study of its physiology and of its implications in human pathologies; title: Lithium, the seminal GSK-3 inhibitor; title: Inhibition of GSK-3 as therapeutic strategy in disease : efficacy of AR-A014418; title: TDZD's: selective and ATP noncompetitive glycogen synthase kinase 3 inhibitors; title: 3-amino pyrazoles as potent and selective glycogen kinase synthase (GSK-3) inhibitors; title: Marine compounds as a new source for glycogen synthase kinase 3 inhibitors.