Protective groups in organic synthesis.
Contributors: Wuts, Peter G. M.
Edition: 3rd ed. / Theodora W. Greene and Peter G.M. Wuts.
Publisher: Wiley
Published: 1999
Place of publication: New York
Language: eng
Number of pages: 779
Subjects: Organic compounds -- Synthesis; Protective groups (Chemistry)
Description: This edition provides readers with a comprehensive compendium of 1,050 of the most useful protective groups as well as 5,350 references to original publications. Protective groups are organized by six major organic functional groups: hydroxyl, amino, carboxyl, carbonyl, sulfhydryl, and phosphate groups (the last new to this edition). Also added in this edition are protection of the alkyne-CH, expanded coverage of protection of all groups, and many new enzymatic methods of protection and deprotection. Each chapter briefly describes the classes of available protective groups, followed by an in-depth look at the chemistry of individual protective groups, their properties, and the best methods of formation and cleavage. Ten reactivity charts with more than 28,000 entries summarize the relative reactivities of 270 commonly used protective groups with 108 reagents.
Notes: Includes bibliographical references and index.
"A Wiley-Interscience publication."