The art of drug synthesis
By: edited by Douglas S. Johnson and Jie Jack Li.
Contributors: Johnson, Douglas S. 1968-; Li, Jie Jack.
Publisher: John Wiley & Sons
Published: 2007
Place of publication: Hoboken, N.J
Language: eng
Number of pages: 276
ISBN-13: 9780471752158
Subjects: Drugs -- Design; Pharmaceutical chemistry; Drug Design; Chemistry, Pharmaceutical -- methods
Notes: Includes bibliographical references and index.
Table of contents: title: The role of mechanical chemistry in drug discovery; title: Process research: how much? how soon?; title: Aromatase inhibitors for breast cancer; title: Quinolone antibiotics; title: Triazole antifungals; title: Non-nucleoside HIV reverse transcription inhibitors; title: Neuraminidase inhibitors for influenza; title: Peroxisome proliferator-activated receptor (PPAR) agonists for type 2 diabetes; title: Angiotensin AT1 antagonists for hypertension; title: Leading ACE inhibitors for hypertension; title: Dihydropyridine calcium channel blockers for hypertension; title: 2nd generation HMG-CoA reductase inhibitors; title: Cholesterol absorption inhibitors: ezetimibe (zetia); title: Dual service serotonin and norepinephrine reuptake inhibitors (SSNRI) for depression; title: Gaba receptor agonists for insomnia; title: Ligands: neurontin? (gabapentin) and lyrica? (pregabalin); title: Approved treatments for attention deficit hyperactivity disorder (ADHD).