The chaperonopathies
Subtitle: diseases with defective molecular chaperones : an introduction and guide to diseases in which chaperones play an etiologic-pathogenic role
By: Alberto J. L. Macario, Everly Conway de Macario, Francesco Cappello
Contributors: Conway de Macario, Everly, author; Cappello, Francesco, author
Series: SpringerBriefs in biochemistry and molecular biology; SpringerBriefs in biochemistry and molecular biology
Publisher: Springer
Published: 2013
Place of publication: Dordrecht; New York
Language: eng
Number of pages: 116
ISBN-13: 9789400746664; 9789400746671
Copyright date: 2013
Subjects: Molecular chaperones; Diseases; Causes and theories of causation; Medical microbiology; Molecular Chaperones; Analysis; Disease; Etiology; Protein Folding
Description: This Brief provides a concise review of chaperonopathies, i.e., diseases in which molecular chaperones play an etiologic-pathogenic role. Introductory chapters deal with the chaperoning system and chaperoning teams and networks, HSP-chaperone subpopulations, the locations and functions of chaperones, and chaperone genes in humans. Other chapters present the chaperonopathies in general, including their molecular features and mechanistic classification into by defect, excess, or mistake. Subsequent chapters discuss the chaperonopathies in more detail, focusing on their distinctive characteristic.
Notes: Includes bibliographical references.