Aging of the genome
Subtitle: the dual role of the DNA in life and death
By: Jan Vijg.
Publisher: Oxford University Press; Oxford University Press, USA
Published: 2007
Place of publication: Oxford ; New York
Language: eng
Number of pages: 372
ISBN-13: 9780198569237; 9780198569220
Subjects: Aging -- Genetic aspects; Apoptosis; Genomes; Developmental genetics; DNA damage
Description: Aging has long been ascribed to the gradual accumulation of mutations in the genome. However, it is only recently that the technology has been developed to test this theory and its consequences. This book reviews the concept of genomic instability as a possible universal cause of aging in complex organisms.