Antimicrobial Roles for iNKT Cells and GM-CSF in Mycobacterium Tuberculosis Infection
Contributors: Behar, Samuel M.; Winau, Florian; Starnbach, Michael; Cooper, Andrea; Brenner, Michael
Published: 2014
Language: eng
Description: Despite effective antibiotics, Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis, still infects nearly one-third of the world's population. While key immune factors including CD4+ T cells and IFNg production have been identified, there are still many antimicrobial mechanisms yet to be explored. Here we characterized the role of invariant natural killer T (iNKT) cells and GM-CSF during Mtb infection.
Notes: Keywords: GM-CSF, immunology, iNKT cells, Mtb, Tuberculosis.

Thesis Ph.D. Harvard University 2014