Effects of non-digestible oligosaccharides and viscous fiber on serum lipid risk factors and colonic fermentation in hyperlipidemic subjects.
Published: 2005
Language: eng
Number of pages: 190
Description: To determine whether the addition of an inulin and oligofructose mixture (FOS) to a diet containing oat bran lowered serum cholesterol more than oat bran or FOS alone, we conducted a randomized controlled crossover trial at a teaching hospital clinic. Twenty-six hypercholesterolemic adults each took three 4-week treatments: oat bran bread plus 10 grams FOS, oat bran bread plus 10 g maltodextrin, and 10 grams FOS plus wheat bran bread, with 1-week minimum washout between phases. Subjects followed an Adult Treatment Panel III step 2 diet. Serum lipids, colonic microflora, breath gases, and fecal short-chain fatty acids were measured. No treatment reduced serum lipids and no differences between treatments were seen. Changes from time zero in bifidobacteria did not relate to changes in LDL-Cholesterol (P&ge;0.408). In conclusion, we found no effects of FOS or oat bran on serum lipids.	This may relate to beta-glucan hydrolysis by gluten added to the bread.
Notes: Source: Masters Abstracts International, Volume: 44-02, page: 0819.

Thesis (M.Sc.)--University of Toronto, 2005.

Electronic version licensed for access by U. of T. users.

GERSTEIN MICROTEXT copy on microfiche (2 microfiches).