Genetic variance detection
Subtitle: nuts & bolts of DHPLC in genomics
By: edited by Karl Heinz Hecker.
Contributors: Hecker, Karl Heinz.
Series: The nuts & bolts series
Publisher: DNA Press
Published: 2003
Place of publication: [Eagleville, PA]
Language: eng
Number of pages: 189
Subjects: DNA -- Analysis.; Chromatographic analysis.; Variation (Biology); Genomics.; DNA Mutational Analysis.; Chromatography, High Pressure Liquid.
Notes: Includes bibliographical references and index.
Table of contents: title: Basics of automated, high-accuracy mutation screening with the WAVE Nucleic Acid Fragment Analysis Systems / Karl H. Hecker; title: Influence of PCR on DHPLC polymorphism characterization / Michael L. Nickerson; title: Denaturing high performance liquid chromatography (DHPLC), an important mutation detection technique in mutation analysis of the breast and ovarian cancer predisposing genes BRCA1 and BRCA2 / Norbert Arnold and Dieter Niederacher; title: Mutation detection in the tuberous sclerosis genes TSC1 and TSC2 by DHPLC / Penelope S. Roberts, Sandra L. Dabora, David J. Kwiatkowski; title: Rapid analysis to detect base changes in human mitochondrial DNA by restriction enzyme analysis followed by denaturing high performance liquid chromatography / Patricia E. McAndrew and Michael A. Marino; title: Mutation analysis of LDLR mutations in patients with familial hypercholesterolaemia / Caroline F. Bunn and Peter M. George; title: Novel DHPLC based strategy for identification and characterization of (bi)-clonal T-cell receptor targets for the detection of minimal residual disease in childhood acute lymphoblastic leukemia / Udo zur Stadt ... [et al.]; title: SIRPH : a rapid, quantitative SNuPE-IP RP HPLC method for simultaneous methylation analysis at multiple CpG sites / Osman El-Maarri, Johannes Oldenburg and Jörn Walter; title: Isolation and sequencing of heteroduplex fragments from DHPCL analysis of somatic, low-frequency mutations / Jan Alsner; title: Analysis of promoter methylation using denaturing high-performance liquid chromatography (DHPLC) / Beate Betz and Dieter Niederacher.