S-Adenosylmethionine-Dependent Methyltransferases
Subtitle: Structures and Functions
Contributors: Robert M. Blumenthal (Editor)
Publisher: World Scientific Publishing Company
Published: July 2000
Language: eng
Format: Hardcover
Number of pages: 400
ISBN-13: 9789810238704
Subjects: Enzymology; Science; Science/Mathematics; Life Sciences - Biochemistry; Mechanics - General
First sentence: It was in the 1940s that Du Vigneaud and colleagues found that a substantial fraction of the methyl groups in cell metabolites derived from methionine, and in the 1950s [10] Cantoni and colleagues found that the actual methyl donor is the ATP-activated form of methionine, S-adenosyl-L-methionine (AdoMet).
Description: "This volume, written by an international group of scientists, presents an overview of the AdoMet-dependent methyltransferases, with special emphasis on structure-function relationships. S-adenosyl-L-methionine (AdoMet) is the second most commonly used enzyme cofactor after ATP. The AdoMet-dependent methyltransferases act on a wide variety of target molecules, including DNA, RNA, proteins, polysaccharides, lipids, and a range of small molecules."--Jacket.