Therapeutic oligonucleotides
Subtitle: methods and protocols
By: edited by John Goodchild
Series: Methods in molecular biology -- 764; Springer protocols; Methods in molecular biology (Clifton, N.J.) -- v. 764.; Springer protocols
Publisher: Humana Press; Springer
Published: 2011
Place of publication: New York
Language: eng
Number of pages: 340
ISBN-13: 9781617791871; 9781617791888
Subjects: Therapeutic use; Oligonucleotides
Notes: Includes bibliographical references and index.
Table of contents: title: Therapeutic oligonucleotides  -- John Goodchild; title: Dinucleotides containing 3-S-phosphorothiolate linkages  -- James W. Gaynor and Richard Cosstick; title: 2-O,4-C-methyleneoxymethylene bridged nucleic acids (2,4-BNACOC)  -- Yoshiyuki Hari ... [et al.]; title: Non-covalent peptide-based strategy for ex vivo and in vivo oligonucleotide delivery  -- Laurence Crombez ... [et al.]; title: Cell-penetrating peptides-based strategies for the delivery of splice redirecting antisense oligonucleotides  -- Samir El Andaloussi ... [ et al.]; title: Nanoparticle for tumor targeted delivery of oligomers  -- Xinrong Liu, Yi Wang, and Donald J. Hnatowich; title: Light-directed delivery of nucleic acids  -- Sigurd Bøe ... [et al.]; title: Antibody targeted siRNA delivery  -- Masoud M. Toloue and Lance P. Ford; title: Aptamer-drug conjugation for targeted tumor cell therapy  -- Michael J. Donovan ... [et al.]; title: Five-step process for screening antisense compounds for efficacy: gene target IL-12Rb2  -- Nikki B. Marshall, Laura L. Hauck, and Dan V. Mourich; title: Diverse small non-coding RNAs in RNA interference pathways  -- Liande Li and Yi Liu; title: Quantification of siRNAs in vitro and in vivo  -- Angie Cheng, Alexander V. Vlassov, and Susan Magdaleno; title: Optimization of transfection conditions and analysis of siRNA potency using real-time PCR  -- Angie Cheng, Susan Magdaleno, and Alexander V. Vlassov; title: siRNA knockdown of gene expression in endothelial cells  -- Emily Dennstedt and Brad Bryan; title: Using RNA interference in Schistosoma mansoni  -- Rita Bhardwaj, Greice Krautz-Peterson, and Patrick J. Skelly; title: Performing the labeled microRNA pull-down (LAMP) assay system : an experimental approach for high-throughput identification of microRNA-target mRNAs  -- Ren-Jun Hsu and Huai-Jen Tsai; title: Synthesis, purification, and characterization of oligoribonucleotides that act as agonists of TLR7 and/or TLR8  -- Tao Lan and Ekambar R. Kandimalla; title: Synthesis, purification, and characterization of immune-modulatory oligodeoxynucleotides that act as agonists of toll-like receptor 9  -- Mallikarjuna Reddy Putta, Dong Yu, and Ekambar R. Kandimalla; title: Surface plasmon resonance investigation of RNA aptamer-RNA ligand interactions  -- Carmelo Di Primo, Eric Dausse, and Jean-Jacques Toulme; title: Practical considerations for analyzing antigene RNAs (agRNAs) : RNA immunoprecipitation of argonaute protein  -- Jacob C. Schwartz and David R. Corey; title: Inhibition of human papillomavirus expression using DNAzymes -- Maria Luisa Benitez-Hess, Pablo Reyes-Gutierrez, and Luis Marat Alvarez-Salas.