Cell-penetrating peptides
Subtitle: methods and protocols
By: edited by Ülo Langel
Series: Springer protocols; Methods in molecular biology -- 683; Springer protocols (Series); Methods in molecular biology (Clifton, N.J.) -- v. 683.
Publisher: Humana
Published: 2011
Place of publication: New York
Language: eng
Number of pages: 586
Subjects: Peptides; Physiological transport; Drug carriers (Pharmacy); Pharmacokinetics; Biological Transport; Physiology; Drug Carriers
Notes: Includes bibliographical references and index.
Table of contents: title: Classes and prediction of cell-penetrating peptides; title: Penetratin story: An overview; title: Testing membrane interactions of CPPs; title: Interactions of amphipathic CPPs with model membranes; title: NMR studies of three-dimensional structure and positioning of CPPs in membrane model systems; title: Measurements of the intracellular stability of CPPs; title: Tools for predicting binding and insertion of CPPs into lipid bilayers; title: Studies of proteoglycan involvement in CPP-mediated delivery; title: Uptake kinetics of cell-penetrating peptides; title: Thermodynamics of lipid interactions with cell-penetrating peptides; title: Calcium and membrane repair; title: Mapping of protein transduction pathways with fluorescent microscopy; title: Insight into cell-entry mechanisms of CPPs by electron microscopy; title: Toxicity methods for CPPs; title: Comparison of CPP uptake methods; title: Characterization of cellular internalization pathways for CPP-mediated oligonucleotide delivery; title: Mimicry of protein function with cell-penetrating peptides; title: Homeoprotein intercellular transfer, the hidden face of cell-penetrating peptides; title: Pharmacology, biodistribution, and efficacy of GPCR-based pepducins in disease models; title: Identification and characterization of tissue-specific protein transduction domains using peptide phage display; title: Applications of cell-penetrating peptides as signal transduction modulators for the selective induction of apoptosis; title: Splice redirection as a convenient assay to monitor CPP-on efficiency and mechanism; title: CPP-directed oligonucleotide exon skipping in animal models of Duchenne muscular dystrophy; title: PTD-DRBD siRNA delivery; title: A non-covalent peptide-based strategy for siRNA delivery; title: Application of pepfect peptides for the delivery of splice-correcting oligonucleotides; title: Internalization of nucleoside phosphates into live cells by complex formation with different CPPs and JBS-nucleoducin; title: Enhanced cellular delivery of cell-penetrating peptide-peptide nucleic acid conjugates by photochemical internalization; title: Identification of homing peptides using the in vivo phage display technology; title: Measuring the action of CPP-siRNA conjugates in the lung; title: Intracellular delivery of nanoparticles with CPPs; title: Multifunctional CPP polymer system for tumor-targeted pDNA and siRNA delivery; title: Cell-penetrating penta-peptides and bax-inhibiting peptides: Protocol for their application; title: Pair technology: Exon-specific rna-binding protein isolation in live cells; title: Quantitation of cellular and topical uptake of luciferin-oligoarginine conjugates; title: Industrial-scale manufacturing of a possible oligonucleotide cargo CPP-based drug; title: Application of a fusiogenic peptide GALA for intracellular delivery; title: Therapeutic applications of cell-penetrating peptides; title: Nonclinical and clinical experiences with CPP-based self-assembling peptide systems in topical drug development .