relative efficacy and safety of tetracaine and morphine for the relief of pain from peripherally inserted central catheter placement in neonates.
Published: 2004
Language: eng
Number of pages: 130
Description: Purpose. To compare the efficacy and safety of tetracaine, morphine and the combination of tetracaine and morphine for peripherally inserted central catheter (PICC) placement in neonates.Results. Ninety-three infants completed the study. No differences in pain response were measured. Tetracaine was associated with more local, transient erythema than placebo. An increase in ventilation rate occurred with morphine compared to placebo.Conclusions. There was no difference in analgesic efficacy among the three treatment groups. The use of morphine was associated with more systemic effects. Its routine use cannot be recommended over tetracaine. (Abstract shortened by UMI.)
Notes: Adviser:  Gideon Koren.

Thesis (M.Sc.)--University of Toronto, 2004.

Electronic version licensed for access by U. of T. users.

Source: Masters Abstracts International, Volume: 42-06, page: 2178.

MICR copy on microfiche (2 microfiches).