Molecular neurosurgery with targeted toxins
By: edited by Ronald G. Wiley and Douglas A. Lappi.
Contributors: Wiley, Ronald G., 1947-; Lappi, Douglas A.
Publisher: Humana Press
Published: 2005
Place of publication: Totowa, N.J
Language: eng
Number of pages: 311
Subjects: Neurotoxic agents -- Therapeutic use.; Drug targeting.; Antibody-toxin conjugates -- Therapeutic use.; Immunotoxins -- therapeutic use.; Antibodies, Monoclonal -- therapeutic use.; Cholinergic Fibers -- metabolism.; Neurobiology -- methods.; Neurons -- pathology.
Notes: Includes bibliographical references and index.
Table of contents: value: Introduction to molecular neurosurgery / Ronald G. Wiley and Douglas A. Lappi; value: Ribosome-inactivating proteins / Fiorenzo Stirpe; value: Biochemical, physiological, and behavioral characterizations of the cholinergic basal forebrain lesion produced by 192 IgG-saporin / Jerene J. Waite; value: Basal forebrain cholinergic lesion by 192 IgG-saporin: a tool to assess the consequences of cortical cholinergic dysfunction in Alzheimers disease / Reinhard Schliebs; value: 192 IgG-saporin-induced partial cortical cholinergic deafferentation as a model for determining the interactions between brain aging and neurodevelopmental defects in the cortical cholinergic input system / Martin Sarter and John P. Bruno; value: Exploring the role of acetylcholine in primate cognition using Me20.4 IgG-saporin / Rosalind M. Ridley and Harry F. Baker; value: Cortical cholinergic deafferentation induces A-beta deposition: towards a physiologic animal model of Alzheimer's disease / Thomas G. Beach ... [et al.]; value: Chemical dissection of brain glucoregulatory circuitry / Sue Ritter ... [et al.]; value: Cardiovascular deficits after lesions of C1 adrenergic neurons with a saporin-based immunotoxin / Patrice G. Guyenet, Ruth L. Stornetta, and Ann M. Schreihofer; value: Saporin conjugates and pain / Ronald G. Wiley and Douglas A. Lappi; value: The use of saporin conjugates to dissect neurons responsible for sleep and wakefulness / Carlos Blanco-Centurion ... [et al.]; value: Isolectin I-B4-mediated cytotoxic targeting of sensory neurons / Lucy Vulchanova and Christopher N. Honda; value: B fragment of cholera toxin conjugated to saporin / Peter T. O'hara, Kanwarjit Kelley, and Luc Jasmin.