Relaxin and related peptides
By: edited by Alexander I. Agoulnik.
Contributors: Agoulnik, Alexander I.
Series: Advances in experimental medicine and biology -- v. 612
Publisher: Springer Science+Business Media; Landes Bioscience
Published: 2007
Place of publication: New York; Austin, Tex
Language: eng
Number of pages: 142
ISBN-13: 9780387746708
Subjects: Relaxin; Relaxin -- physiology; Receptors, G-Protein-Coupled -- physiology; Receptors, Peptide -- physiology
Description: This book discusses the established paradigms, the contradictions, and the most recent findings and future directions in the field of relaxin research. The array of diverse topics are highlighted, ranging from evolution of relaxin family peptides and receptors to their cell signaling, from the role of relaxin in reproduction to the newly discovered functions in cancer progression and in the nervous system. This book includes chapters written by well-known experts in the relaxin field who are actively involved in shaping this rapidly evolving science. The four major ongoing areas of research described in this book will likely attract investigators for years to come, since many basic scientific questions remain unanswered at this time. The availability of structural databases, new experimental techniques, and high quality hormone preparations, antibodies and other reagents enable rigorous investigation. This book offers a fresh perspective along with different points of view, o.
Notes: Includes bibliographical references and index.
Table of contents: title: The evolution of the relaxin peptide family and their receptors / Tracey N. Wilkinson and Ross A.D. Bathgate; title: Relaxin, the relaxin-like factor and their receptors / Christian Schwabe and Erika E. Bu llesbach; title: Diverse signalling mechanisms used by relaxin in natural cells and tissues: the evolution of a "neohormone" / Richard Ivell, Kee Heng and Ravinder Anand-Ivell; title: Relaxin physiology in the female reproductive tract during pregnancy / Laura J. Parry and Lenka A. Vodstrcil; title: Relaxin and related peptides in male reproduction / Alexander I. Agoulnik; title: The vascular actions of relaxin / Arundhathi Jeyabalan ... [et al.]; title: The effects of relaxin on extracellular matrix remodeling in health and fibrotic disease / Chrishan S. Samuel, Edna D. Lekgabe, and Ishanee Mookerjee; title: Relaxin-like ligand-receptor systems: are autocrine/paracrine effectors in tumor cells and modulate cancer progression and tissue invasiveness / Thomas Klonisch ... [et al.]; title: Relaxin-family peptide and receptor systems in brain: insights from recent anatomical and functional studies / Sherie Ma and Andrew L. Gundlach.