Alzheimer's disease and frontotemporal dementia
Subtitle: methods and protocols
By: edited by Erik D. Roberson
Series: Methods in molecular biology -- 670; Springer protocols; Methods in molecular biology (Clifton, N.J.) -- v. 670.; Springer protocols
Publisher: Humana Press
Published: 2011
Place of publication: New York
Language: eng
Number of pages: 277
ISBN-13: 9781607617433; 9781607617440
Subjects: Frontotemporal Dementia; Neurological Models; Alzheimer's disease; Alzheimer Disease; Dementia
Notes: Includes bibliographical references and index.
Table of contents: title: Contemporary approaches to Alzheimer's disease and frontotemporal dementia / Erik D. Roberson; title: Preparing synthetic A[beta] in different aggregation states / W. Blaine Stine ... [et al.]; title: Isolation of low-n amyloid [beta]-protein oligomers from cultured cells, CSF, and brain / Ganesh M. Shankar ... [et al.]; title: Detecting A[beta]*56 oligomers in brain tissues / Mathew A. Sherman and Sylvain E. Lesné; title: Assessing A[beta] aggregation state by atomic force microscopy / Justin Legleiter; title: Measuring APP carboxy-terminal fragments / Luke A. Esposito; title: Detection of APP intracellular domain in brain tissue / Sanjay W. Pimplikar and Anupama Suryanarayana; title: Cell-based assays for regulators of tau biology / Umesh K. Jinwal and Chad A. Dickey; title: Split GFP complementation assay for quantitative measurement of tau aggregation in situ / Wanjoo Chun, Geoffrey S. Waldo, and Gail V.W. Johnson; title: Apolipoprotein E expression and purification / Yvonne Newhouse and Karl H. Weisgraber; title: A[beta] toxicity in primary cultured neurons / Adriana Ferreira ... [et al.]; title: Manipulation of gene expression in the central nervous system with lentiviral vectors / Binggui Sun and Li Gan; title: Selecting a mouse model of Alzheimer's disease / Jeannie Chin; title: Monitoring spatial learning and memory in Alzheimer's disease mouse models using the Morris water maze / Kimberly Scearce-Levie; title: Step-by-step in situ hybridization method for localizing gene expression changes in the brain / Jorge J. Palop, Erik D. Roberson, and Inma Cobos; title: Real-time visualization of axonal transport in neurons / Yasuko Osakada and Bianxiao Cui; title: Quantifying biomarkers of cognitive dysfunction and neuronal network hyperexcitability in mouse models of Alzheimer's disease : depletion of calcium-dependent proteins and inhibitory hippocampal remodeling / Jorge J. Palop, Lennart Mucke, and Erik D. Roberson; title: Epigenetic changes in the brain : measuring global histone modifications / Gavin Rumbaugh and Courtney A. Miller.