Prions and prion diseases
Subtitle: current perspectives
By: edited by Glenn C. Telling
Contributors: Telling, Glenn C
Publisher: Horizon Bioscience
Published: 2004
Place of publication: Norfolk, Eng
Language: eng
Number of pages: 307
Subjects: Prions; Prion diseases
Description: Research into prions and prion diseases has progressed at a rapid pace in recent years, and has shed new light on areas such as transmissible spongiform encephalopathies. Telling (Center on Aging, University of Kentucky) provides an overview of the pathogenesis, molecular biology, biochemistry, cellular biology, animal models, and immunology of prions, for researchers working in microbiology, molecular biology, and biochemistry, and for those in pharmaceutical and biotechnology companies. Specific topics include the prion protein in cell culture, binding and conversion reactions between prion protein isoforms, PrP deletion mutants, and targeting the murine PrP gene. Other subjects are transgenic mouse models of prion diseases, peripheral pathogenesis, and immunological advances in prion diseases.
Notes: Includes bibliographical references and index