G Protein Coupled Receptors
Subtitle: Essential Methods
Contributors: Wheatley, Mark
Publisher: John Wiley & Sons
Published: 2010
Place of publication: Chichester
Language: eng
Format: [electronic resource] :
Number of pages: 312
ISBN-13: 9780470749227
Description: G-Protein Coupled Receptors (GPCRs) are not only the largest protein family in the human genome but are also the single biggest target for therapeutic agents. Research into GPCRs is therefore growing at a fast pace and the range of techniques that can be applied to GPCRs is vast and continues to grow. This book provides an invaluable bench-side guide into the best and most up-to-date techniques for current and future research on GPCRs. With contributions from leading international authorities, this book equips readers with clear and detailed protocols for both well-known and up-and-coming tech.
Notes: Description based on print version record.
Table of contents: title: 7 Using Intramolecular Fluorescence Resonance Energy Transfer to Study Receptor Conformation8 A Disulfide Cross-linking Strategy Useful for Studying Ligand-induced Structural Changes in GPCRs; 9 Use of Fluorescence Correlation Spectroscopy to Study the Diffusion of G Protein-coupled Receptors; 10 Identification and Analysis of GPCR Phosphorylation; 11 Measurement and Visualization of G Protein-coupled Receptor Trafficking by Enzyme-linked Immun.