Biochips As Pathways To Drug Discovery
Publisher: CRC Press
Published: 2006
Place of publication: Hoboken
Language: eng
Format: [electronic resource]
Number of pages: 420
ISBN-13: 9781420015607
Subjects: Biochips
Description: The DNA microarray field is expected to thrive in the coming years, expanding into areas of robotics, nucleic acid chemistries, and informatics. With perspectives that look ahead to the future of this area, ''Biochips as Pathways to Drug Discovery'' provides a comprehensive overview of the current state of biochip technology, examining the effects of biochips on biomedical research and specifically the pharmaceutical industry. This text presents technology platforms in detail and explores the clinical relevance of biochips, Chip-chip assays, and high-throughput approaches in depth. It also cov.
Notes: Description based on print version record.
Table of contents: title: Front cover; Preface; Acknowledgments; The Editors; Contributors; Table of Contents; Chapter 1. DNA Biochips; title: Past, Present, and Future: An Overview; Chapter 2. Three-Dimensional HydroArrays: Novel Microarrays for Genomic and Proteomic Studies; Chapter 3. Biochips in Malaria for Antiparasitic Discovery; Chapter 4. Regional Variations in Intestinal ATP-Binding Cassette Transporter Expression Identified with a Global Error Assessment Model*; Chapter 5. Toxicogenomics in Drug Safety Evaluation: Bridging Drug Discovery and Development.; title: Chapter 6. The Next Generation of Automated Microarray Platforms for a Multiplexed CYP2D6 AssayChapter 7. Evaluation of Skeletal Muscle and Adipose Tissue Biopsy Procedures for Microarray-Based Gene-Expression Profiling; Chapter 8. ChIP-on-Chip: Analysis of Genomewide Protein Binding and Posttranslational Modifications; Chapter 9. DNA Microarrays as Functional Genomics Tools for Cancer Drug Discovery; Chapter 10. High-Throughput Microarray Analysis; Chapter 11. La.