Clinical pharmacokinetics and pharmacodynamics
Subtitle: concepts and applications
By: Malcolm Rowland and Tom Tozer.
Contributors: Tozer, Thomas N.; Rowland, Malcolm.
Edition: 4th ed.
Publisher: Lippincott William & Wilkins
Published: 2009
Place of publication: Philadelphia
Language: eng
ISBN-13: 9780781750097
Subjects: Pharmacokinetics; Chemotherapy; Pharmacokinetics; Drug Therapy
Notes: Rev. ed. of: Clinical pharmacokinetics. 1995.
Table of contents: title: Therapeutic relevance; title: Fundamental concepts and terminology; title: Kinetics following an intravenous bolus dose; title: Membranes and distribution; title: Elimination; title: Kinetics following an extravascular dose; title: Absorption; title: Response following a single dose; title: Therapeutic window; title: Constant-rate input; title: Multiple dose regimens; title: Variability; title: Genetics; title: Age, weight, and gender; title: Disease; title: Nonlinearities; title: Drug interactions; title: Initiating and managing therapy; title: Distribution kinetics; title: Metabolites and drug response; title: Protein drugs; title: Prediction and refinement of human kinetics from in vitro, preclinical, and early clinical data.