siRNA and miRNA gene silencing
Subtitle: from bench to bedside
By: edited by Mouldy Sioud.
Contributors: Sioud, Mouldy.
Series: Methods in molecular biology -- 487; Springer protocols; Methods in molecular biology (Clifton, N.J.) -- v. 487.; Springer protocols
Publisher: Humana Press; Springer [distributor]
Published: 2009
Place of publication: New York, NY; London
Language: eng
Number of pages: 472
ISBN-13: 9781603275460; 9781603275477
Subjects: Small interfering RNA; Gene silencing; RNA, Small Interfering -- therapeutic use; Gene Silencing; MicroRNAs -- therapeutic use; Petit ARN d'interférence -- usage thérapeutique; Inactivation d'un gène; Interférence ARN
Notes: Includes bibliographical references and index.
Table of contents: title: Methods for selecting effective siRNA sequences by using statistical and clustering techniques / Shigeru Takasaki; title: Deciphering the code of innate immunity recognition of siRNAs / Mouldy Sioud; title: Targeted delivery of anitsense oligonucleotides and siRNAs into mammalian cells / Mouldy Sioud; title: Local and systemic delivery of siRNAs for oligonucleotide therapy / Fumitaka Takeshita ... [et al.]; title: Imaging of siRNA delivery and silencing / Anna Moore and Zdravka Medarova; title: Recent advances in magnetofection and its potential to deliver siRNAs in vitro / Olga Mykhaylyk ... [et al.]; title: In vitro and in vivo gene silencing by TransKingdom RNAi (tkRNAi) / Shuanglin Xiang ... [et al.]; title: Bacterial delivery of siRNAs : a new approach to solid tumor therapy / De-Qi Xu ... [et al.]; title: The therapeutic potential of LNA-modified siRNAs : reduction of off-target effects by chemical modification of the siRNA sequence / Kees Fluiter, Olaf R.F. Mook, and Frank Baas; title: pSM155 and pSM30 vectors for miRNA and shRNA expression / Junzhu Wu, Akua N. Bonsra, and Guangwei Du; title: Targeting oncogenes with siRNAs / Olaf Heidenreich; title: Targeting stromal-cancer cell interactions with siRNAs / Seyedhossein Aharinejad ... [et al.]; title: Therapeutic potential of siRNA-mediated targeting of urokinase plasminogen activator, its receptor, and matrix metalloproteinases / Christopher S. Gondi and Jasti S. Rao; title: Silencing of HIF-1[alpha] by RNA interference in human glioma cells in vitro and in vivo / David L. Gillespie ... [et al.]; title: RNA interference-mediated validation of genes involved in telomere maintenance and evasion of apoptosis as cancer therapeutic targets / Marco Folini, Marzia Pennati, and Nadia Zaffaroni; title: Treating respiratory viral diseases with chemically modified, second generaton intranasal siRNAs/ Sailen Barik; title: Progress in the therapeutic applications of siRNAs against HIV-1 / Miguel Angel Martínez; title: Protein components of the microRNA pathway and human diseases / Marjorie P. Perron and Patrick Provost; title: Intron-mediated RNA interference and microRNA biogenesis / Shao-Yao Ying and Shi-Lung Lin; title: Emergence of a complex relationship between HIV-1 and the microRNA pathway / Dominique L. Ouellet ... [et al.]; title: Synthetic microRNA targeting glioma-associated antigen-1 protein / Naotake Tsuda ... [et al.]; title: Therapeutic targeting of gene expression by siRNAs directed against BCR-ABL transcripts in a patient with Imatinib-resistant chronic myeloid leukemia / Michael Koldehoff and Ahmet H. Elmaagacli.