Telomerase inhibition
Subtitle: strategies and protocols
By: edited by Lucy G. Andrews and Trygve O. Tollefsbol.
Contributors: Tollefsbol, Trygve O.
Series: Methods in molecular biology -- 405; Methods in molecular biology (Clifton, N.J.) -- 405
Publisher: Humana; Quantum [distributor
Published: 2007
Place of publication: Totowa, N.J
Language: eng
Number of pages: 193
ISBN-13: 9781588296832
Subjects: Telomerase -- Inhibitors; Telomerase -- Laboratory manuals; Telomerase -- antagonists & inhibitors; Urinary Bladder Neoplasms -- drug therapy; Drug Therapy; Oligonucleotides
Genres: Laboratory manuals
Notes: Includes bibliographical references and index.
Table of contents: title: Methods of telomerase inhibition; title: Telomerase inhibition by synthetic nucleic acids and chemosensitization in human bladder cancer cell lines; title: hTERT knockdown in human embryonic kidney cells using double-stranded RNA; title: RNA interference using a plasmid construct expressing a short-hairpin RNA; title: Retrovirus-mediated RNA interference; title: Telomerase inhibition and telomere targeting in hematopoietic cancer cell lines with small non-nucleosidic synthetic compounds (BIBR1532); title: Uses of telomerase peptides in anti-tumor immune therapy; title: Establishing cell-based reporter systems for the analysis of hTERT expression; title: Telomerase RNA inhibition using antisense oligonucleotide against human telomerase RNA linked to a 2',5'-oligoadenylate; title: Knockdown of telomerase RNA using hammerhead ribozymes and RNA interference; title: Evaluation of tankyrase inhibition in whole cells; title: Inhibition of telomerase by targeting MAP kinase signaling; title: Screening of telomerase inhibitors; title: Telomerase inhibition combined with other chemotherapeutic reagents to enhance anti-cancer effect.