Polymer Based Systems on Tissue Engineering, Replacement and Regeneration
By: edited by Rui L. Reis, Daniel Cohn
Contributors: Cohn, Daniel
Series: NATO Science Series, Series II: Mathematics, Physics and Chemistry, 1568-2609 -- 86; NATO science series -- 86.
Publisher: Springer Netherlands; Imprint; Springer
Published: 2002
Place of publication: Dordrecht
Language: eng
Format: [electronic resource] /
Number of pages: 440
ISBN-13: 9789401003056
Other titles: Proceedings of the NATO Advanced Study Institute, held in Alvor, Algarve, Portugal, 15-25 October 2001
Description: Biodegradable, polymer-based systems are playing an increasingly pivotal role in tissue engineering replacement and regeneration. This type of biology-driven materials science is slated to be one of the key research areas of the 21<SUP>st</SUP> century. The following aspects are crucial: the development of adequate human cell culture to produce the tissues in adequate polymer scaffold materials; the development of culture technology with which human tissues can be grown ex-vivo in 3D polymer matrices; the development of material technology for producing the degradable, 3D matrices, having mechanical properties similar to natural tissue. In addressing these and similar problems, the book contains chapters on biodegradable polymers, polymeric biomaterials, surface modification for controlling cell-material interactions, scaffold design and processing, biomimetic coatings, biocompatibility evaluation, tissue engineering constructs, cell isolation, characterisation and culture, and controlled release of bioactive agents.