The bottleneck
Subtitle: gamete and embryo mitochondria in humans : proceedings of a Serono Symposia Australasia Symposium held in Sydney, Australia, May 7-8, 1999, in association with the 11th World Congress on In-Vitro Fertilization and Human Reproductive Genetics
By: edited by Robert P.S. Jansen.
Contributors: Jansen, Robert, 1946-; European Society of Human Reproduction and Embryology.; Serono Symposia Australasia Symposium (1999 : Sydney, N.S.W.); World Congress on In Vitro Fertilization & Human Reproductive Genetics (11th : 1999 : Sydney, N.S.W.)
Publisher: Published for the European Society for Human Reproduction and Embryology by Oxford University Press
Published: 2000
Place of publication: Oxford, UK
Language: eng
Number of pages: 260
Subjects: Mitochondria; Embryonic Development -- genetics; Germ Cells
Other titles: Gamete and embryo mitochondria in humans
Notes: "Human reproduction, volume 15, supplement 2, July 2000."

"These proceedings were sponsored by the Ares-Serono Foundation and Serono Symposia Australasia"

Includes bibliographical references and index.
Table of contents: title: Origin and persistence of the mitochondrial genome; title: Transcription and replication of mitochondrial DNA; title: Genetic control of oxidative phosphorylation and experimental models of defects; title: Genetic defects causing human mitochondrial respiratory chain disorders and disease; title: Organismal effects of mitochondrial dysfuntion; title: Practical problems in detecting abnormal mitochondrial function and genomes; title: Morphological correlates of mitochondrial dysfunction in children; title: In-vitro genetic modification of mitochondrial function; title: Regulation of mitochondrial DNA copy number during spermatogenesis; title: Fertilization and elimination of the paternal mitochondrial genome; title: Evolutionary origin and consequences of uniparental mitochondrial inheritance; title: Germline passage of mitochondria: quantitative considerations and possible embryological sequelae; title: Mitochondrial morphology in human fetal and adult female germ cells; title: Mitochondrial morphology during preimplantational human embryogenesis; title: Chromosomal non-disjunction in human oocytes: is there a mitochondrial connection?; title: Intrafollicular influences on human oocyte developmental competence: perifollicular vascularity, oocyte metabolism and mitochondrial function; title: Mitochondrial distribution and function in oocytes and early embryos; title: Toxic effects of oxygen on early human embryo development; title: Spontaneous and artificial changes in human ooplasmic mitochondria; title: Mitochondrial ultrastructure in embryos after implantation; title: Mitochondrial segregation in the developing embryo; title: Transmission of the human mitochondrial genome; title: Towards reliable prenatal diagnosis of mtDNA point mutations: studies of nt8993 mutations in oocytes, fetal tissues, children and adults.