The p53 family
Subtitle: a subject collection from Cold Spring Harbor Perspectives in biology
By: edited by Arnold J. Levine, David P. Lane
Publisher: Cold Spring Harbor Laboratory Press
Published: 2010
Place of publication: Cold Spring Harbor, N.Y
Language: eng
Number of pages: 360
ISBN-13: 9780879698300
Subjects: Collected Works; Genes, p53; P53 antioncogene
Other titles: Cold Spring Harbor perspectives in biology.
Notes: Includes bibliographical references and index.
Table of contents: title: The origins and evolution of the p53 family of genes / Vladimir A. Belyi ... [et al.]; title: The tumor suppressor p53: from structures to drug discovery / Andreas C. Joerger and Alan R. Fersht; title: The isoforms of the p53 protein / Marie P. Khoury and Jean-Christophe Bourdon; title: p63 and p73, the ancestors of p53 / Volker Dötsch ... [et al.]; title: Transcriptional regulation by p53 / Rachel Beckerman and Carol Prives; title: Posttranslational modification of p53: cooperative integrators of function / David W. Meek and Carl W. Anderson; title: The regulation of the p53-mediated stress response by MDM2 and MDM4 / Mary Ellen Perry; title: Tied up in loops: positive and negative autoregulation of p53 / Xin Lu; title: Tp53 mutations in human cancers: origins, consequences, and clinical use / Magali Olivier, Monica Hollstein, and Pierre Hainaut; title: Clinical outcomes and correlates of TP53 mutations and cancer / Ana I. Robles and Curtis C. Harris; title: Single-nucleotide polymorphisms in the p53 signaling pathway / Lukasz F. Grochola ... [et al.]; title: Tumor suppressive functions of p53 / Jack T. Zilfou and Scott W. Lowe; title: p53 regulation of metabolic pathways / Eyal Gottlieb and Karen H. Vousden; title: p53 regulation of the IGF-1/AKT/mTOR pathways and the endosomal compartment / Zhaohui Feng; title: The role of p53 gene family in reproduction / Wenwei Hu; title: Using mice to examine p53 functions in cancer, aging, and longevity / Lawrence A. Donehower; title: Mutant p53 gain-of-function in cancer / Moshe Oren and Varda Rotter; title: Mouse models of p53 functions / Guillermina Lozano; title: Zebrafish models of p53 functions / Narie Y. Storer and Leonard I. Zon; title: Phylogeny and function of the invertebrate p53 superfamily / Rachael Rutkowski, Kay Hofmann, and Anton Gartner; title: P53-based cancer therapy / David P. Lane, Chit Fang Cheok, and Sonia Lain; title: Pathologies associated with the p53 response / Andrei V. Gudkov and Elena A. Komarova; title: P53 research: the past thirty years and the next thirty years / David Lane and Arnold Levine.