Cysteine proteases of pathogenic organisms
By: edited by Mark W. Robinson, PhD, Infection, Immunity and Innovation (i3) Institute, University of Technology Sydney, Ultimo, Sydney, Australia, John P. Dalton, PhD, Institute of Parasitology, McDonald Campus, McGill University, St. Anne de Bellevue, Quebec, Canada
Series: Advances in experimental medicine and biology -- v. 712; Advances in experimental medicine and biology -- v. 712.
Publisher: Springer Science+Business Media; Landes Bioscience
Published: 2011
Place of publication: New York; Austin, Tex
Language: eng
Number of pages: 226
ISBN-13: 9781441984135
Subjects: Cysteine proteinases; Cysteine Proteases; Pathogenic microorganisms; Eukaryota; Pathophysiology; Microbial enzymes; Enzymology; Viruses; Immunology; Chemistry; Bacteria
Description: Cysteine proteases expressed by pathogenic organisms play key roles in virulence including host entry, feeding and suppression of host immune responses. This book gives comprehensive coverage to all aspects of pathogen cysteine proteases and brings together numerous scientific advances which have been made over many years. Thus, the biochemistry, molecular biology and structure function relationships of these important pathogen enzymes are covered in detail. Written by leading researchers from Europe, Australia and North America, this book is essential reading for students and professionals interested in human medicine and infectious disease research --Provided by publisher.
Notes: Machine generated contents note: Papa In Like Proteases Of Staphylococcus Aureus.- The Lysine Specific Gingipain Of Porphyromonas: Importance To Pathogenicity.- Falcipains And Other Cysteine Proteases Of Malaria Parasites.- Cathepsin Proteases In Toxoplasma Gondii.- Entamoeba Histolytica Cathepsin Like Enzymes.- Cysteine Peptidases Of Kinetoplastid Parasites.- Cruzain: The Path From Target Validation To The Clinic.- The Phylogeny, Structure And Function Of Trematode Cysteine Proteases, With Particular Emphasis On The Fasciola Hepatica Cathepsin L Family.- Cathepsins B1 And B2 Of Trichobilharzia Spp., Bird Schistosomes Causing Cercarial Dermatitis.- Proteases In Blood Feeding Nematodes And Their Potential As Vaccine Candidates.- Cysteine Proteases From Bloodfeeding Arthropod Ectoparasites.- How Pathogen Derived Cysteine Proteases Modulate Host Immune Responses.- Cystatins Of Parasitic Organisms.

Includes bibliographical references and index.
Table of contents: title: Papain-like proteases of staphylococcus aureus; title: Lysine specific gingipain of Porphyromonas gingivalis: importance to pathogenicity and potential strategies for inhibition; title: Falcipains and other cysteine proteases of malaria parasites; title: Cathepsin proteases in Toxoplasma gondii; title: Entamoeba Histolytica cathepsin-like enzymes; title: Cysteine peptidases of kinetoplastid parasites; title: Cruzain: the path from target validation to the clinic; title: Phylogeny, structure and function of trematode cysteine proteases, with particular emphasis on the Fasciola hepatica cathepsin L family; title: Cathepsins B1 and B2 of Trichobilharzia spp., bird schistosomes causing cercarial dermatitis; title: Proteases in blood feeding nematodes and their potential as vaccine candidates; title: Cysteine proteases from bloodfeeding arthropod ectoparasites; title: How pathogen derived cysteine proteases modulate host immune responses; title: Cystatins of parasitic organisms.