Untangling the double helix
By: James C. Wang.
Publisher: Cold Spring Harbor Laboratory Press
Published: 2009
Place of publication: Cold Spring Harbor, N.Y
Language: eng
Number of pages: 233
ISBN-13: 9780879698638; 9780879698799
Subjects: DNA topoisomerases -- Popular works
Genres: Popular works.
Table of contents: title: An insuperable problem; title: Nature's solutions: the DNA topoisomerases; title: Breaking a DNA strand and holding onto; title: The broken ends; title: A magic swivel; title: Moving one DNA double helix through another; title: Real-time viewing of the DNA topoisomerases in action; title: Manifestations of DNA entanglement: replication and recombination; title: Manifestations of DNA entanglement: transcription and gene expression; title: Beyond DNA untanglement: new twists on an old; title: Theme; title: From nature's battlefields to the clinical wards; title: Appendix 1: identification of the covalent intermediates in topoisomerase-catalyzed reactions; title: Appendix 2 catalysis of dna breakage and rejoining by dna topoisomerases.