Molecular biology of cancer
Subtitle: mechanisms, targets, and therapeutics
By: Lauren Pecorino,  University of Greenwich
Edition: Third edition.
Publisher: Oxford University Press
Published: 2012
Language: eng
Number of pages: 342
ISBN-13: 9780199577170
Subjects: Molecular aspects; Cancer cells; Cancer
Description: Demonstrating how the malfunction of normal molecular pathways and components can lead to cancer, this text explores how our understanding of these defective mechanisms can be harnessed to develop new targeted therapeutic agents.
Notes: Includes bibliographical references and index.
Table of contents: title: DNA structure and stability : mutations versus repair; title: Regulation of gene expression; title: Growth factor signaling and oncogenes; title: The cell cycle; title: Growth inhibition and tumor suppressor genes; title: Apoptosis; title: Stem cells and differentiation; title: Metastasis; title: The immune system, infections, and inflammation; title: Nutrients, hormones, and gene interactions; title: The cancer industry : drug development, pharmocogenomics, and clinical trial design; title: Cancer in the future : focus on cancer vaccines and technology.