Handbook of basic pharmacokinetics-- including clinical applications
By: Wolfgang A. Ritschel, Gregory L. Kearns.
Contributors: Kearns, Gregory L.; American Pharmacists Association.
Edition: 6th ed.
Publisher: American Pharmacists Association
Published: 2004
Place of publication: Washington, D.C
Language: eng
Number of pages: 432
Subjects: Pharmacokinetics
Notes: Includes bibliographical references and index.
Table of contents: title: Definitions and glossary; title: The LADMER system: liberation, absorption, distribution, metabolism, elimination, and response; title: Organs, tissues, cells, and organelles; title: Cell membranes; title: Drug-receptor interactions; title: Absorption/transport mechanisms; title: pKa and degree of ionization; title: Lipid/water partition coefficient; title: Physicochemical factors altering biological performance of drugs; title: Biopharmaceutical data of the gastrointestinal tract; title: Fluid compartments and circulatory system; title: Binding of drugs to biological material; title: Drug biotransformation; title: Compartment models; title: Determination of rate constants; title: Volume of distribution and distribution coefficient; title: Excretion and clearance of drugs; title: Urinary and biliary recycling.; title: Cumulative urinary excretion; title: Area under the blood level-time curve; title: Pharmacokinetics of single dose administration; title: Pharmacokinetics of multiple dosing; title: Compartment model independent analysis; title: Pediatric pharmacokinetics; title: Drug dosage in elderly patients; title: Drug dosage in obese patients; title: Drug disposition in pregnancy; title: Dosage regimen design; title: Drug monitoring and dosage adjustment; title: Physiological and pathological factors influencing drug response; title: First dosage size in man; title: Forensic pharmacokinetics; title: Nonlinear pharmacokinetics; title: Curve fitting; title: Correlation of clinical response with drug disposition; title: Bioavailability and bioequivalence; title: Body surface areas; title: Extracorporeal methods of drug removal; title: Pharmacogenetics and pharmacogenomics.