Validation of cell-based assays in the GLP setting
Subtitle: a practical guide
By: edited by Uma Prabhakar and Marian Kelley.
Contributors: Prabhakar, Uma.; Kelley, Marian.
Publisher: Wiley
Published: 2008
Place of publication: Chichester, England; Hoboken, NJ
Language: eng
ISBN-13: 9780470028766
Subjects: Pharmaceutical biotechnology -- Laboratory Manuals; Animal cell biotechnology -- Laboratory Manuals; Biological assay -- Validity -- Laboratory Manuals; Cytochemical bioassay -- Validity -- Laboratory Manuals; Biological Assay -- methods -- Laboratory Manuals
Genres: Laboratory Manuals; Laboratory Manuals.
Notes: Includes bibliographical references and index.
Table of contents: title: Considerations while setting up cell-based assays / Marian Kelley; title: Development, optimization and validation of cell based assays 1 / Marielena Mata and Thomas Lohr; title: Development, optimization and validation of cell based assays 2 / Manjula Reddy and Uma Prabhakar; title: Whole blood ex vivo stimulation assay development, optimization and validation / Manjula Reddy and Uma Prabhakar; title: Immunohistochemistry assays in GLP studies / Frank Lynch ... [et al.]; title: Flow cytometric cell based assays : an overview of general applications / Cuc Davis ... [et al.]; title: T-cell surface markers in human peripheral whole blood using flow cytometry / Manjula Reddy ... [et al.]; title: Intracellular cytokine detection by flow cytometry / Julie G. Wilkinson, Carlos A. Aparicio and Wade E. Bolton; title: Validating reference samples for comparison in regulated ELISPOT assay / Magdalena Tary-Lehmann, Christina D. Hamm and Paul V. Lehmann; title: IFN-[gamma] ELISPOT assay validation / Manjula Reddy ... [et al.]; title: IL-5 ELISPOT assay validation / Manjula Reddy ... [et al.]; title: Validation of the cylex technology to measure T and B cell activation capacity in clinical trials / Marielena Mata, Thomas Lohr and Jaymala Patel; title: Development of validated neutralization bioassays / Manoj Rajadhyaksha ... [et al.]; title: Endpoint assays in HIV-1 vaccine trials : functioning in a GLP environment / Patricia D'Souza ... [et al.]; title: The future direction of cell-based assays / Uma Prabhakar and Marian Kelley.