Vasomotor rhinitis
Subtitle: a series of pilot studies to assess the feasibility of a randomized clinical trial of topical nasal steroids versus cryotherapy treatments.
Published: 2005
Language: eng
Number of pages: 150
Description: Introduction. Medical and surgical therapies are available to treat vasomotor rhinitis but it is unclear if there is an advantage of one treatment over another.Methods. Three pilot studies were performed to assist in the design and feasibility of a randomized clinical trial (RCT) comparing the effects of a topical nasal steroid against inferior turbinate cryotherapy.Results. The first study tested the stability of posterior rhinomanometry and acoustic rhinometry over 6 months in normal subjects. Posterior rhinomanometry values varied significantly whereas acoustic rhinometry results were stable. The second study assessed a nasal symptom diary which was found to have good internal consistency as well as face and content validity. The third study was a pilot RCT of topical nasal steroids versus inferior turbinate cryotherapy in 10 patients.Conclusions. A future RCT would require more patients than is feasible unless significantly more effort is put into recruitment than the pilot RCT.
Notes: Source: Masters Abstracts International, Volume: 44-02, page: 0843.

Thesis (M.Sc.)--University of Toronto, 2005.

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