Drug-drug interactions
By: edited by A. David Rodrigues.
Contributors: Rodrigues, A. David.
Edition: 2nd ed.
Series: Drugs and the pharmaceutical sciences -- 179; Drugs and the pharmaceutical sciences -- v. 179.
Publisher: Informa Healthcare
Published: 2008
Place of publication: New York
Language: eng
Number of pages: 744
ISBN-13: 9780849375934
Subjects: Drug interactions.; Pharmacokinetics.; Drug Interactions.; Pharmaceutical Preparations -- metabolism.; Pharmacokinetics.
Notes: Includes bibliographical references and index.
Table of contents: value: Introducing pharmacokinetic and pharmacodynamic concepts / Malcolm Rowland; value: In vitro enzyme kinetics applied to drug-metabolizing enzymes / Kenneth R. Korzekwa; value: Human cytochromes P450 and their role in metabolism-based drug-drug interactions / Stephen E. Clarke and Barry C. Jones; value: UDP-glucuronosyltransferases / Rory P. Remmel, Jin Zhou, and Upendra A. Argikar; value: Drug-drug interactions involving the membrane transport process / Hiroyuki Kusuhara and Yuichi Sugiyama; value: In vitro models for studying induction of cytochrome P450 enzymes / Jose M. Silva and Deborah A. Nicoll-Griffith; value: In vitro approaches for studying the inhibition of drug-metabolizing enzymes and identifying the drug-metabolizing enzymes responsible for the metabolism of drugs (reaction phenotyping) with emphasis on cytochrome P450 / Brian W. Ogilvie ... [et al.]; value: ^The role of P-glycoprotein in drug disposition: significance to drug development / Matthew D. Troutman ... [et al.]; value: ^Cytochrome P450 protein modeling and ligand docking / K. Anton Feenstra, Chris de Graaf, and Nico P.E. Vermeulen; value: Role of the gut mucosa in metabolically based drug-drug interactions / Kenneth E. Thummel, Danny D. Shen, and Nina Isoherannen; value: Mechanism-based inhibition of human cytochromes P450: in vitro kinetics and in vitro-in vivo correlations / Xin Zhang, David R. Jones, and Stephen D. Hall; value: Transporter-mediated drug interactions: molecular mechanisms and clinical implications / Jiunn H. Lin; value: Metabolism and transport drug interaction database: a web-based research and analysis tool / Houda Hachad, Isabelle Ragueneau-Majlessi, and René H. Levy; value: In vivo probes for studying induction and inhibition of cytochrome P450 enzymes in humans / Grant R. Wilkinson; value: ^Drug-drug interactions: clinical perspective / David J. Greenblatt and Lisa L. von Moltke; value: ^An integrated approach to assessing drug-drug interactions: a regulatory perspective / Shiew-Mei Huang, Lawrence J. Lesko, and Robert Temple; value: Drug-drug interactions: toxicological perspectives / Sidney D. Nelson; value: Drug-drug interactions: marketing perspectives / Kevin J. Petty and Jose M. Vega.