Principles of Bone Biology
Publisher: Academic Press
Published: January 2002
Format: Hardcover
Number of pages: 1696
ISBN-13: 9780120986545
Subjects: Physiology; Medical / Nursing
Table of contents: value: Part I Basic Principles A. Cell Biology Chapter 1: Structure, Modeling and Remodeling of Bone / The Size and Shape of Bone as a Site of Metabolic Bone Activity Ego Seeman Chapter 2: Biomechanics of Bone Elise Morgan Chapter 3: Embryonic Development of Bone and the Molecular Regulation of Intramembranous and Endochondral Bone Formation Andrew Karaplis Chapter 4: Mesenchymal Stem Cells & Osteoblast Lineage Jane Aubin Chapter 5: Transcriptional Control of Osteoblast Differentiation and Function Thorsten Schinke Chapter 6: Wnt Signaling and Bone Mark Johnson Chapter 7: Sclerostin and Bone Rutger van Bezooijen Chapter 8: The Osteocyte Jenneke Klein-Nulend Chapter 9: Cells of Bone: Osteoplast Generation Tatsuo Suda Chapter 10: Osteoclast Function: Biology and Mechanisms Kalervo Vaananen Chapter 11: RANK Signaling Hiroshi Takanayagi Chapter12: Regulating Bone Resorption Roland Baron Chapter 13: Apoptosis in Bone Cells Stavros Manolagas Chapter 14: Skeletal Gene Expression in Nuclear Microenvironments Gary Stein B. Biochemistry Chapter 15: Type I Collagen: Structure, Synthesis, and Regulation Benoit de Crombrugghe Chapter 16: Collagen Crosslinking & Metabolism Simon Robins Chapter 17: Bone Matrix Proteoglycans & Glycoproteins Pamela Robey Chapter 18: Osteopontin Masaki Noda Chapter 19: Bone Proteinases Nicola Partridge Chapter 20: Integrins and Other Cell Surface Attachment Molecules of Bone Cells Michael Horton Chapter 21: Intercellular Junctions and Cell-Cell Communication in the Skeletal System Roberto Civitelli C. Bone Remodeling and Mineral Homeostasis Chapter 22: Histomorphometric Analysis of Bone Remodeling David Dempster Chapter 23: Phosphorus Homeostasis & Related Disorders Marc Drezner Chapter 24: Magnesium Homeostasis Robert Rude Chapter 25: Metals in Bone: Aluminum, Boron, Cadmium, Chromium, Lead, Silicon, & Stro Felix Bronner Chapter 26: Biology of the Extracellular Ca2+-Sensing Receptor Edward Brown D. The Hormones of Bone Chapter 27: Receptors for Parathyroid Hormone (PTH) and PTH-Related Protein John Potts Chapter 28: Parathyroid Hormone - Molecular Biology Hank Kronenberg Chapter 29: Parathyroid Hormone-Receptor Interactions Mike Rosenblatt Chapter 30: Actions of Parathyroid Hormone on the Vasculature and Cardiovascular System John Bilezikian Chapter 31: The Vascular and Cardiovascular Actions of PTH John Bilezikian Chapter 32: PTH and PTHrP Actions on Kidney and Bone Peter Friedman Chapter 33: Physiological Actions of Parathyroid Hormone and PTH-Related Protein John Wysolmerski Chapter 34: Vascular, Cardiovascular and Neurological Actions of Parathyroid-Related Protein Thomas Clemens Chapter 35: Vitamin D Nuclear Receptor (VDR) and Plasma Vitamin D-Binding Protein (DBP) Structures and Ligand Shape Preferences for Genomic and Rapid Biological Responses Tony Norman Chapter 36: Vitamin D Gene Regulation Sylvia Christakos Chapter 37: Photobiology and Non-Calcemic Actions of Vitamin D Mike Holick Chapter 38: Calcitonin Structure and Molecular Biology of the Calcitonin Receptor / Calcitonin Gene Family and Receptors: Structure, Molecular Biology, and Effects Bob Gagel Chapter 39: Amylin and Calcitonin Gene-Related Peptide Jill Cornish E. Other Systemic Hormones That Influence Bone Metabolism Chapter 40: Estrogens & Progestins Russell Turner Chapter 41: The Pharmacology of Selective Estrogen Receptor Modulators Henry Bryant Chapter 42: Mechanisms of Estrogen Action in Bone Roberto Pacifici Chapter 43: Thyroid Hormone & Bone Paula Stern Chapter 44: Clinical and Basic Aspects of Glucocorticoid Action in Bone Barbara Kream Chapter 45: Effects of Diabetetes & Insulin on Bone Physiology Johan Verhaeghe Chapter 46: Androgens:Receptor Expression and Steroid Action in Bone Kristine Wiren Chapter 47: Kinins & Neuro-Osteogenic Factors Ulf Lerner Chapter 48: Regulation of Bone Remodeling by Central and Peripheral Nervous Signals Patricia Ducy F. Local Regulators Chapter 49: Insulin-like Growth Factors and the IGF Binding Proteins: Implications for Bone Biology Cliff Rosen Chapter 50: Platelet-Derived Growth Factor & the Skeleton Ernesto Canalis Chapter 51: Fibroblast Growth Factor (FGF) and FGF Receptor Families in Bone Marja Hurley Chapter 52: Vascular Endothelial Growth Factor and Osteogenic-Angiogenic Coupling Dwight Towler Chapter 53: Transforming Growth Factor-a Sarah Dallas Chapter 54: Bone Morphogenetic Proteins and the Skeleton Vicki Rosen Chapter 55: Bone Morphogenetic Protein Receptors & Actions Kohei Miyazono Chapter 56: Colony-Stimulating Factor-1 Willy Hofstetter Chapter 57: Local Regulators of Bone: IL-1, TNF, Lymphotoxin, Interferon-?, IL-8, IL-10, IL-4, the LIF/IL-6 Family, and Additional Cytokines Mark Horowitz Chapter 58: Prostaglandins & Bone Metabolism Carol Pilbeam  Part II Molecular Mechanisms of Metabolic Bone Disease Chapter 59: Skeletal Effects of Nitric Oxide: Novel Agent for Osteoporosis Sunil Wimalawansa Chapter 60: Molecular Basis of PTH Overexpression Andy Arnold Chapter 61: Familial Benign Hypocalciuric Hypercalcemia and Neonatal Primary Hyperparathyroidism Ghada EI-Hajj Fuleihan Chapter 62: Multiple Endocrine Neoplasia Type I Maria Luisa Brandi Chapter 63: Parathyroid Hormone-Related Peptide and Other Systemic Factors in Skeletal Manifestations of Malignancy David Goltzman Chapter 64: Local Factors in Skeletal Malignancy Greg Mundy Chapter 65: Genetic Regulation of the Parathyroid Gland Development Raj Thakker Chapter 66: Jansen's Metaphyseal Chondrodysplasia & Blomstrand's Lethal Chondrodysplasia: Two Genetic Disorders Caused by PTH/PTHrP Receptor Mutations Harald Jueppner Chapter 67: Diseases Resulting from Defects in the G Protein Gs Lee Weinstein Chapter 68: Renal Osteodystrophy – Pathogenic Mechanisms and Therapeutic Options Bill Goodman Chapter 69: Osteogenesis Imperfecta David Rowe Chapter 70: Hereditary Deficiencies in Vitamin D Action Uri Liberman Chapter 71: Oncogenic Osteomalacia Suzanne Jan de Beur Chapter 72: Osteopetrosis Lyndon Key Chapter 73: Hypophosphatasia: Nature's Window on Alkaline Phosphatase Function in Humans Michael Whyte Chapter 74: Paget's Disease of Bone Fred Singer Chapter 75: Genetic Determinants of Bone Mass and Osteoporotic Fracture Stuart Ralston Chapter 76: Pathophysiology of Osteoporosis Bilezikian, Raisz, Martin Chapter 77: Evaluation of Risk for Osteoporosis Fracture Stuart Silverman  Part III Pharmacological Mechanisms of Therapeutics Chapter 78: Parathyroid Hormone Dave Hanley Chapter 79: Calcium Robert Heaney Chapter 80: Drugs Acting on the Calcium Receptor Calcimimetics and Calcilytics Edward Nemeth Chapter 81: Bisphosphonates: Mechanisms of Action Graham Russell Chapter 82: The Pharmacology of Estrogens in Osteoporosis Robert Lindsay Chapter 83: Vitamin D & Analogs Glenville Jones Chapter 84: Estrogen Effects on Bone in the Male Skeleton Luigi Gennari Chapter 85: Mechanisms of Exercise Effects on Bone Quantity and Quality Clint Rubin  Part IV Methods in Bone Research Chapter 86: Application of Transgenic Mice to Problems of Skeletal Bone Stephen Clark Chapter 87: Biochemical Markers of Bone Metabolism Markus Seibel Chapter 88: Methods and Clinical Issues in Bone Densitometry Glen Blake Chapter 89: Controversial Issues in Bone Densitometry Paul Miller Chapter 90: Macro and Micro Imaging of Bone Architecture Klaus Engelke, Sven Prevrhal, and Harry K. Genant