Medicinal chemistry and drug design
By: edited by Deniz Ekinci
Publisher: IntechOpen
Published: 2012
Language: eng
Number of pages: 406
ISBN-13: 9789535105138
Description: Over the recent years, medicinal chemistry has become responsible for explaining interactions of chemical molecules processes such that many scientists in the life sciences from agronomy to medicine are engaged in medicinal research. This book contains an overview focusing on the research area of enzyme inhibitors, molecular aspects of drug metabolism, organic synthesis, prodrug synthesis, in silico studies and chemical compounds used in relevant approaches. The book deals with basic issues and some of the recent developments in medicinal chemistry and drug design. Particular emphasis is devoted to both theoretical and experimental aspect of modern drug design. The primary target audience for the book includes students, researchers, biologists, chemists, chemical engineers and professionals who are interested in associated areas. The textbook is written by international scientists with expertise in chemistry, protein biochemistry, enzymology, molecular biology and genetics many of which are active in biochemical and biomedical research. We hope that the textbook will enhance the knowledge of scientists in the complexities of some medicinal approaches; it will stimulate both professionals and students to dedicate part of their future research in understanding relevant mechanisms and applications of medicinal chemistry and drug design.
Notes: "Published online: 16 May, 2012."

Includes bibliographical references.

Description based on online resource; title from resource home page (InTech, viewed June 20, 2013).
Table of contents: title: Kojic acid derivatives; title: Analysis of protein interaction networks to prioritize drug targets of neglected-diseases pathogens; title: Recent applications of quantitative-structure activity relationships in drug design; title: Atherosclerosis and antihyperlipidemic agents; title: Inhibitors of serine proteinase: application in agriculture and medicine; title: Regulation of EC-SOD in hypoxic adipocytes; title: Development of an ultrasensitive CRP latex agglutination reagent by using amino acid spacers; title: Pattern recognition receptors based immune adjuvants: their role and importance in vaccine design; title: Microarray analysis in drug discovery and biomarker identification; title: Supraventricular tachycardia due to dopamine infused through epidural catheter accidentally: a case report and review; title: Effective kinetic methods and tools in investigating the mechanism of action of specific hydrolases; title: Aluminium: non-essential activator of pepsin: kinetics and thermodynamics; title: Peptides and peptidomimetics in medicinal chemistry; title: Carbonic anhydrase inhibitors and activators: small organic molecules as drugs and prodrugs; title: Stochastic simulation for biochemical reaction networks in infectious disease; title: Alternative perspectives of enzyme kinetic modeling; title: Molecular modeling and simulation of membrane transport proteins.