USE OF DEUTERIUM OXIDE AS AN ESTIMATOR OF MILK INTAKE AND BODY COMPOSITION OF NURSING PIGS AND THE EFFECT OF OXYTOCIN ADMINISTRATION TO THE DAM ON EARLY LACTATIONAL PERFORMANCE (SWINE, WATER KINETICS).
Contributors: University of Kentucky.
Published: 1984
Number of pages: 208
Subjects: Agriculture, Animal Culture and Nutrition.
Description: Analysis of D(,2)O (0 to 700 ppm added) in sublimates of biological fluids by infrared spectrophotometry was determined to have a standard deviation (S.D.) of 2.6 ppm on repeated measurements.

The relationship of D(,2)O measured water inflow (WI) with known milk intake (MI) was determined in 2 studies involving 30 pigs. The WI/MI relationship (factor) averaged .944 (S.D. = .049) and .923 (S.D. = .041) in 2 day old pigs for 12 and 24 hour periods, respectively. The absolute difference between WI and MI averaged 14 g (S.D. = 12.5) with 251 g intake and 39 g (S.D. = 20.5) with 502 g intake for 12 and 24 hour periods, respectively. Eighteen, 12 day old pigs fed for 72 hours had an average factor of .955 (S.D. = .028) and difference of 67 g (S.D. = 42.5) when fed 1504 g, or a factor of .897 (S.D. = .035) and difference of 266.8 g (S.D. = 87.3) when fed 2696 g. To adjust WI to reflect MI, the factor was predicted by: Factor = .9864 - .000347(g of weight gain/kg metabolic body weight); r('2) = .32.

Estimates of MI in 20 to 24 day old pigs determined by the weight suckle (WS) technique were 26% less than WI (29.1 g/hour for WS, 36.6 g/hour for WI). WI adjusted by estimated factor averaged 39.5 g/hr.

Equilibration of D(,2)O in body water was complete by 40 or 20 minutes post-injection when injected intravenously and intramuscularly, respectively. Equilibration did not occur within 200 minutes when injected intraperitoneally.

Body fat and protein contents were accurately estimated from the relationships of D(,2)O pool and body weight. Estimates based on D(,2)O pool space (kg) at 120 minutes post-injection were: Protein (kg) = -.0795 + .0407 (D(,2)O space) + .1374 (BW,kg); r('2) = .99: Fat(kg) = -.1022 -.1760 (D(,2)O space) + .1374 (BW,kg); r('2) = .91.

Administration of oxytocin (20 USP units, 5 times daily for 3 days) to sows (22 sows/treatment) increased (P < .05) the initial 24 hour weight gain of pigs (91.1 g vs. 64.2 g). Oxytocin administration did not influence (p > .10) milk composition but tended (p < .10) to decrease MI of pigs during therapy period (1.532 vs. 1.609 kg). MI during the 3 days post therapy averaged 2.269 kg and 2.653 kg for treated and control groups, respectively.
Notes: Source: Dissertation Abstracts International, Volume: 46-01, Section: B, page: 0010.

Thesis (PH.D.)--UNIVERSITY OF KENTUCKY, 1984.

School code: 0102.