Medicinal chemistry
Subtitle: principles and practice
By: edited by Frank D. King
Contributors: King, Frank D; RSC Medicinal Chemistry School (7th : 1993 : University of Kent)
Publisher: Royal Society of Chemistry; CRC Press
Published: 1994
Place of publication: Cambridge
Language: eng
Number of pages: 313
Subjects: Pharmaceutical chemistry
Notes: "Lectures presented at the 7th RSC Medicinal Chemistry School held between 28th June and 3rd July in 1993 at the University of Kent, Canterbury, UK"--Pref

Includes bibliographical references and subject index
Table of contents: title: An introduction to drug-receptor interactions / Barry Hunt; title: Signal transduction and second messengers / Trevor J. Franklin; title: Enzyme inhibitors / David A. Roberts; title: The biological evaluation of new compounds / Robert A. Coleman; title: Pharmacokinetics / Robert M.J. Ings; title: Drug metabolism / Colin Vose; title: Physicochemical properties and drug design / Nigel P. Gensmantel; title: Quantitative structure-activity relationships / Andrew M. Davis; title: Considerations for the use of computational chemistry techniques by medicinal chemists / Mike M. Hann; title: 'Patent medicine' / Bill Tyrrell; title: Molecular biology : a new route to drug discovery / Janet E. Carey; title: Devising a research strategy / Colin W. Greengrass; title: Past approaches to discovering new drugs as medicines / C. Robin Ganellin; title: Bioisosteres, conformational restriction and pro-drugs : approaches to lead optimisation, case history : an example of a conformational restriction approach / Frank D. King; title: The design and synthesis of selective protein kinase C inhibitors / Christopher H. Hill; title: Discovery of 1069C : a novel synthetic antitumour agent with low cross-resistance potential / Simon T. Hodgson; title: The design and biological properties of 'dipeptoid' antagonists / David C. Horwell; title: Migraine therapy : from serotonin to sumatriptan / Peter C. North; title: Drug development / Jane Ormerod