Designing clinical research
By: Stephen B. Hulley ... [et al.].
Contributors: Hulley, Stephen B.
Edition: 3rd ed.
Publisher: Lippincott Williams & Wilkins
Published: 2007
Place of publication: Philadelphia, PA
Language: eng
Number of pages: 367
ISBN-13: 9780781782104
Subjects: Clinical trials.; Medicine -- Research -- Methodology.; Epidemiology -- Research -- Methodology.; Epidemiologic Methods.; Research Design.
Description: Providing a practical guide to planning, tabulating, formulating, and implementing clinical research, with an easy-to-read, uncomplicated presentation. This edition incorporates current research methodology, including molecular and genetic clinical research, and offers an updated syllabus for conducting a clinical research workshop. Emphasis is on common sense as the main ingredient of good science. The book explains how to choose well-focused research questions and details the steps through all the elements of study design, data collection, quality assurance, and basic grant-writing. All chapters have been thoroughly revised, updated, and made more user-friendly.
Notes: Includes bibliographical references and index.
Table of contents: title: Getting started: the anatomy and physiology of clinical research / Stephen B. Hulley, Thomas B. Newman, and Steven R. Cummings; title: Conceiving the research question / Steven R. Cummings, Warren S. Browner, and Stephen B. Hulley; title: Choosing the study subjects: specification, sampling, and recruitment / Stephen B. Hulley, Thomas B. Newman, and Steven R. Cummings; title: Planning the measurements: precision and accuracy / Stephen B. Hulley and Steven R. Cummings; title: Getting ready to estimate sample size: hypotheses and underlying principles / Warren S. Browner, Thomas B. Newman, and Stephen B. Hulley; title: Estimating sample size and power: applications and examples / Warren S. Browner, Thomas B. Newman, and Stephen B. Hulley; title: Designing an observational study: cohort studies / Steven R. Cummings, Thomas B. Newman, and Stephen B. Hulley; title: Designing an observational study: cross-sectional and case-control studies / Thomas B. Newman ... [et al.]; title: Enhancing causal inference in observational studies / Thomas B. Newman, Warren S. Browner, and Stephen B. Hulley; title: Designing a randomized blinded trial / Steven R. Cummings, Deborah Grady, and Stephen B. Hulley; title: Alternative trial designs and implementation issues / Deborah Grady, Steven R. Cummings, and Stephen B. Hulley; title: Designing studies of medical tests / Thomas B. Newman, Warren S. Browner, and Steven R. Cummings; title: Research using existing databases: secondary data analysis, ancillary studies, and systematic reviews / Deborah Grady and Norman Hearst; title: Addressing ethical issues / Bernard Lo; title: Designing questionnaires and interviews / Steven R. Cummings and Stephen B. Hulley; title: Data management / Michael A. Kohn; title: Implementing the study: pretesting, quality control, and protocol revisions / Stephen B. Hulley and Steven R. Cummings.