Label-free technologies for drug discovery
By: editors, Matthew Cooper, Lorenz Mayr
Publisher: John Wiley & Sons
Published: 2011
Place of publication: Chichester, West Sussex, U.K
Language: eng
Number of pages: 322
ISBN-13: 9780470746837
Subjects: Drug development; Drug Discovery; Biosensing Techniques; Drug Design
Notes: Includes bibliographical references and index.
Table of contents: title: The revolution of real-time, label-free biosensor applications / Rebecca L. Rich and David G. Myszka; title: Design and implementation of vertically emitting distributed feedback lasers for biological sensing / Meng Lu ... [et al.]; title: SPR screening of chemical microarrays for fragment based discovery / Thomas Neumann and Renate Sekul; title: The cellkey system : a label-free cell-based assay platform for early drug discovery applications / Ryan P. McGuinness ... [et al.]; title: Dynamic and label-free cell-based assays using the xcelligence system / Yama A. Abassi ... [et al.]; title: Selecting the best HTS hits to move forward : ITC ligand binding characterization provides guidance / Ronan O'Brien & Richard Brown; title: Incorporating transmitted light modalities into high-content analysis assays / Robert Graves; title: Nonradioactive rubidium efflux assay technology for screening of ion channels / Georg C. Terstappen; title: Expanding the scope of HTMS methods / Tom G. Holt ... [et al.]; title: A novel multiplex SPR array for rapid screening and affinity determination of monoclonal antibodies : the proteon XPR36 label free system : kinetic screening of monoclonal antibodies / Vered Bronner, Oded Nahshol, and Tsafrir Bravman; title: Biophysics/label-free assays in hit discovery and verification / Johannes Ottl; title: Harnessing optical label-free on microtiter plates for lead finding from binding to phenotypes / Julio Martin; title: Use of label-free detection technologies in the hit-to-lead process: surface optical detection of cellular processes / F. Stuhmeier ... [et al.]; title: Cellular screening for 7TMS using label-free detection / Jeffrey C. Jerman, Jason Brown, and Magalie Rocheville; title: Novartis evaluation of the ForteBio Octet RED : a versatile instrument for direct-binding experiments / Eric Martin ... [et al.]; title: The pyramid approach to fragment-based biophysical screening / Glyn Williams; title: Characterisation of antibodies against the active conformation of Gài1 using the SRU-BIND label free detection system / Melanie Leveridge, Chun-Wa Chung, and Trevor Wattam; title: SPR based direct binding assays in drug discovery / Walter Huber; title: Kinetic binding mechanisms: their contribution to an optimal therapeutic index / David C. Swinney; title: ITC : more than just binding affinities / Ernesto Freire.