Pre and post-operative CT based morphometric analysis of patients with non-syndromic unilateral coronal synostosis (UCS).
Published: 2005
Language: eng
Number of pages: 89
Description: Unilateral coronal synostosis (UCS) results in significant craniofacial asymmetry and is felt to involve primarily the frontal orbital regions, as well as maxilla and mandible. The purpose of this study was to quantify asymmetry of the craniofacial skeleton in patients with UCS and to assess the impact of anterior cranial vault reconstruction with frontal orbital advancement on the craniofacial skeleton. Thirty-nine patients with non-syndromic UCS with a mean age of 13.3 months underwent surgery. Three-dimensional CT images were utilized to determine asymmetry pre-operatively (T1), immediately post-operatively (T2), and at 1 year-follow up (T3). Paired samples t-test was employed to determine significance at p=0.05.Significant asymmetry exists at the frontal orbital level in patients with non-syndromic UCS. Surgery significantly improved symmetry and normalized subsequent craniofacial growth. This is the first investigation to quantitatively assess maxillary and mandibular development in UCS patients.
Notes: Source: Masters Abstracts International, Volume: 44-02, page: 0809.

Thesis (M.Sc.)--University of Toronto, 2005.

Electronic version licensed for access by U. of T. users.

GERSTEIN MICROTEXT copy on microfiche (1 microfiche).