Lead generation approaches in drug discovery
By: [edited by] Zoran Rankovic, Richard Morphy.
Contributors: Rankovic, Zoran.; Morphy, Richard.
Publisher: Wiley
Published: 2010
Place of publication: Hoboken, N.J
Language: eng
ISBN-13: 9780470257616
Subjects: Drug development; Drugs -- Design; High throughput screening (Drug development); Drug Discovery -- methods; Lead
Notes: Includes bibliographical references and index.
Table of contents: title: Lead discovery : the process / William F. Michne; title: High throughput screening approach to lead discovery / Zoran Rankovic, Craig Jamieson, and Richard Morphy; title: In silico screening / Dagmar Stumpfe, Hanna Geppert, and Jürgen Bajorath; title: Fragment-based lead discovery / Jeffrey S. Albert; title: Design of multi-target ligands / Richard Morphy and Zoran Rankovic; title: De novo drug design / Gisbert Schneider, Markus Hartenfeller, Ewgenij Proschak; title: Role of natural products in drug discovery / Hugo Lachance, Stefan Wetzel, and Herbert Waldmann; title: Early screening for ADMET properties / Dennis A. Smith; title: Role of chemistry in lead discovery / Roland E. Dolle and Karin Worm.