Diet, supplement use and breast cancer
Subtitle: the role of vitamin D.
Published: 2004
Language: eng
Number of pages: 134
Description: We investigated the relationship between dietary and supplemental vitamin D intake and BC risk using data from a larger study. Our study included 1,732 women with invasive BC, and 1,694 age-matched controls. Using unconditional logistic regression, odds ratios (OR) and 95% confidence intervals (CI) were estimated, adjusting for sampling stratum, age, family history, ethnicity, and caloric intake.Pre-menopausal women with the highest quartile of total vitamin D intake had reduced BC risk compared to the lowest quartile (OR  0.67, 95% CI 0.47--0.96). Among post-menopausal women, only vitamin D supplement use >400 I.U./day reduced risk (OR = 0.30, 95% CI 0.15--0.59) compared to never users. Both total vitamin D intake and supplement use >400 I.U./day was associated with a decreased risk only in women with BMI &ge; 25 kg/m2 (OR = 0.59, 95% CI 0.41--0.85 and OR = 0.33, 95% CI 0.15--0.73, respectively). These findings are consistent with the hypothesis that vitamin D reduces the risk of developing BC.
Notes: Adviser: J. Knight.

Thesis (M.Sc.)--University of Toronto, 2004.

Electronic version licensed for access by U. of T. users.

Source: Masters Abstracts International, Volume: 42-06, page: 2191.

MICR copy on microfiche (2 microfiches).