Human embryonic stem cells
By: edited by J. Odorico, S.-C. Zhang, R. Pedersen.
Contributors: Odorico, Jon S.; Zhang, S.-C.; Pedersen, Roger A.
Publisher: Garland Science/BIOS Scientific Publishers
Published: 2006
Place of publication: Abingdon, Oxon, UK
Language: eng
Number of pages: 391
ISBN-13: 9781859962787
Subjects: Embryonic stem cells; Human cell culture
Description: Since the first successful isolation and cultivation of human embryonic stem cells at the University of Wisconsin - Madison in 1998, there have been high levels of both interest and controversy in this area of research. This book provides a concise overview of an exciting field, covering the characteristics of both human embryonic stem cells and pluripotent stem cells from other human cell lineages. The following chapters describe state-of-the-art differentiation and characterization of specific ectoderm, mesoderm and endoderm-derived lineages from human embryonic stem cells, emphasizing how these can be used to study human developmental mechanisms. A further chapter discusses genetic manipulation of human ES cells. The concluding section covers therapeutic applications of human ES cells, as well as addresses the ethical and legal issues that this research has raised.
Table of contents: title: Biology of embryonic stem cells / M.B. Morris ... [et al.]; title: Characteristics of human embryonic stem cells, embryonal carcinoma cells, and embryonic germ cells / M.J. Shamblott and J. Sterneckert; title: Adult stem cell plasticity / R.E. Schwartz and C.M. Verfaillie; title: Human and mouse embryonic stem cell lines : windows to early mammalian development / J.S. Odorico and Su-Chun Zhang; title: Human mesenchymal stem cells and multilineage differentiation to mesoderm lineages / V. Sottile and J. McWhir; title: Trophoblast differentiation from embryonic stem cells / T.G. Golos and Ren-He Xu; title: Current and future prospects for hematopoiesis studies using human embryonic stem cells / D.S. Kaufman; title: Derivation of endothelial cells from human embryonic stem cells / S. Levenberg, N.F. Huang and R. Langer; title: Neural specification from human embryonic stem cells / Su-Chun Zhang; title: Modeling islet development through embryonic stem cell differentiation / J.S. Odorico ... [et al.]; title: Cardiomyocyte differentiation in human embryonic stem cell progeny / I. Kehat, J. Itskovitz-Eldor and L. Gepstein; title: Genetic engineering of human embryonic stem cells / M. Drukker, S.K. Dhara, and N. Benvenisty; title: ES cells for transplantation : coping with immunity / J.A. Bradley, E.M. Bolton, and R.A. Pedersen; title: Clinical applications for human ES cells / T. Kamp and J.S. Odorico; title: Production of human embryonic stem cell-derived cellular product for therapeutic use / R. Mandalam ... [et al.]; title: Ethical and policy considerations in embryonic stem cell research / R. Alta Charo; title: Legal framework pertaining to research creating or using human embryonic stem cells / C.E. Gulbrandsen ... [et al.]; title: Genomic approaches to stem cell biology / T.S. Tanaka ... [et al.]; title: Proteomics and embryonic stem cells / M.R. Sussman ... [et al.].