Novel therapeutic targets for anti-arrhythmic drugs
By: [edited by] George E. Billman.
Contributors: Billman, George E.
Publisher: John Wiley & Sons
Published: 2010
Place of publication: Hoboken, N.J
Language: eng
ISBN-13: 9780470261002
Subjects: Myocardial depressants; Arrhythmia -- Chemotherapy; Anti-Arrhythmia Agents; Arrhythmias, Cardiac -- drug therapy
Notes: Includes bibliographical references and index.
Table of contents: title: Myocardial potassium channels : primary determinants of action potential repolarization; title: The "funny" pacemaker current; title: Arrhythmia mechanisms in ischemia and infarction; title: Antiarrhythmic drug classification; title: Repolarization reserve and proarrhythmic risk; title: Safety challenges in the development of novel antiarrhythmic drugs; title: Safety pharmacology and regulatory issues in the development of antiarrhythmic medications; title: Ion channel remodeling and arrhythmias; title: Redox modification of ryanodine receptors by heart failure and cardiac arrhythmias : a potential therapeutic target; title: Targeting sodium/calcium exchange as an antiarrhythmic strategy; title: Calcium/calmodulin-dependent protein kinase ii (CaMKII) ?; title: Modulation of ion currents and potential role for arrhythmias; title: Selective targeting of ventricular potassium channels for arrhythmia suppression : feasible or risible?; title: Cardiac sarcolemmal atp-sensitive potassium channel antagonists : a class of drugs that may selectively target the ischemic myocardium; title: Mitochondrial origin of ischemia-reperfusion arrhythmias : cardiac mitochondria as a novel target for antiarrhythmic drugs; title: Cardiac gap junction modulators : a new target for antiarrhythmic drugs; title: Novel pharmacological targets for the management of atrial fibrillation; title: Ultra-rapid delayed rectifier potassium current, ikur : a therapeutic target for atrial arrhythmias; title: Non-pharmacologic manipulation of the autonomic nervous system in man for the prevention of life-threatening arrhythmias; title: Effects of endurance exercise training on cardiac autonomic regulation and susceptibility to sudden cardiac death : a non-pharmacological approach for the prevention of ventricular fibrillation; title: Dietary omega-3 fatty acids as a non-pharmacological antiarrhythmic intervention.