Protein misfolding and cellular stress in disease and aging
Subtitle: concepts and protocols
By: edited by Peter Bross and Niels Gregersen
Series: Methods in molecular biology -- 648; Springer protocols; Springer protocols; Methods in molecular biology (Clifton, N.J.) -- v. 648.
Publisher: Humana Press
Published: 2010
Place of publication: New York
Language: eng
Number of pages: 330
ISBN-13: 9781607617556; 9781607617563
Subjects: Cells; Proteins; Protein Folding; Protein folding; Pathophysiology; Pathology; Laboratory Manuals; Physiology; Cellular Pathology
Notes: Includes bibliographical references and index.
Table of contents: title: Protein misfolding and celluar stress : an overview / Niels Gregersen and Peter Bross; title: Protein aggregation diseases : toxicity of soluble prefibrillar aggregates and their clinical significance / Massimo Stefani; title: Consequences of stress in the secretary pathway : the ER stress response and its role in the metabolic syndrome / Martin Schröder and Louise Sutcliffe; title: What role does mitochondrial stress play in neurodegenerative diseases? / Alicia Mae Pickrell and Carlos Torres Moraes; title: Autophagy in disease / Dalibor Mijaljica, Mark Prescott, and Rodney J. Devenish; title: Mitophagy and mitoptosis in disease processes / Dalibor Mijaljica, Mark Prescott, and Rodney J. Devenish; title: Cellular stress and protein misfolding during aging / Rajiv Vaid Basaiawmoit and Suresh I.S. Rattan; title: Measuring consequences of protein misfolding and cellular stress using OMICS techniques / Peter Bross ... [et al.]; title: Production of cells with targeted integration of gene variants of human ABC transporter for stable and regulated expression using the Flp recombinase system / Kanako Wakabayashi-Nakao ... [et al.]; title: Stress response profile in human fribroblasts exposed to heat shock or oxidative stress / Christina Bak Pedersen and Niels Gregersen; title: Examining ubiquitinated protein aggregates in tissue sections / Natalia A. Kaniuk and John H. Brumell; title: Determination of proteasomal activities / Cristovao F. Lima and Suresh I.S. Rattan; title: Measurement of autophagy in cells and tissues / Isei Tanida and Satoshi Waguri; title: Transcription factor sequestration by polyglutamine proteins / Tomoyuki Yamanaka and Nobuyuki Nukina; title: Biological membranes as protein aggregation matrices and targets of amyloid toxicity / Monica Bucciantini and Cristina Cecchi; title: Measurement of mitochondrial ROS production / Anatoly A. Starkov; title: In vivo detection of oxidized proteins : a practical approach to tissue-derived mitochondria / Francesca Maltecca and Giorgio Casari; title: Measurement of oxidized/reduced glutathione ratio / Joshua B. Owen and D. Allan Butterfield; title: Determination of altered mitochondria ultrastructure by electron microscopy / Shoichi Sasaki; title: Assessing bad sub-cellular localization under conditions associated with prevention or promotion of mitochondrial permeability transition-dependent toxicity / Liana Cerioni and Orazio Cantoni; title: A cellular viability assay to monitor drug toxicity / Jakob Hansen and Peter Bross; title: A cellular viability assay to monitor drug toxicity / Jakob Hansen and Peter Bross; title: Rescue of misfolded proteins and stabilization by small molecules / Raymond C. Stevens, Javier Sancho, and Aurora Martinez.