Protein degradation
By: John Mayer, Aaron Ciechanover, Martin Rechsteiner, eds
Contributors: Wiley online library
Publisher: Wiley-VCH
Published: 2005
Place of publication: Weinheim
Language: eng
Format: [electronic resource] /
ISBN-13: 9783527619320
Subjects: Proteins; Ubiquitin; Cell Physiology; Physiology; Metabolism
Notes: Includes bibliographical references and index.

Electronic reproduction. Hoboken, N.J. : Wiley InterScience, 2008. Mode of access: World Wide Web. System requirements: Web browser. Title from title screen (viewed on Feb. 18, 2008). Access may be restricted to users at subscribing institutions.
Table of contents: title: v. 1. Ubiquitin and the chemistry of life. 1. Brief history of protein degradation and the ubiquitin system / Avram Hershko; title: 2. N-terminal ubiquitination: no longer such a rare modification / Aaron Ciechanover; title: 3. Evolutionary origin of the activation step during ubiquitin-dependent protein degradation / Hermann Schindelin; title: 4. RING fingers and relatives: determinators of protein fate / Kevin L. Lorick ... [et al.]; title: 5. Ubiquitin-conjugating enzymes / Michael J. Eddins and Cecile M. Pickart; title: 6. The SCF ubiquitin E3 ligase / Leigh Ann Higa and Hui Zhang; title: 7. The structural biology of ubiquitin-protein ligases / Ning Zheng and Nikola P. Pavletich; title: 8. The deubiquitinating enzymes / Nathaniel S. Russell and Keith D. Wilkinson; title: 9. The 26S proteasome / Martin Rechsteiner; title: 10. Molecular machines for protein degradation / Matthias Bochtler ... [et al.]; title: 11. Proteasome regulator, PA700 (19S regulatory particle) / George N. DeMartino and Cezary Wojcik; title: 12. Bioinformatics of ubiquitin domains and their binding partners / Kay Hofmann; title: 13. The COP9 signalosome: its possible role in the ubiquitin system; title: v. 2. The ubiquitin-proteasome system. 1. Molecular chaperones and the ubiquitin-proteasome system / Cam Patterson and Jörg Höhfeld; title: 2. Molecular dissection of autophagy in the yeast Saccharomyces cerevisiae / Yoshinori Ohsumi; title: 3. Dissecting intracellular proteolysis using small molecule inhibitors and molecular probes / Huib Ovaa ... [et al.]; title: 4. MEKK1: dual function as a protein kinase and a ubiquitin protein ligase / Zhimin Lu and Tony Hunter; title: 5. Proteasome activators / Andreas Förster and Christopher P. Hill; title: 6. The proteasome portal and regulation of proteolysis / Monika Bajorek and Michael H. Glickman; title: 7. Ubiquity and diversity of the proteosome system / Keiji Tanaka, Hideki Yashiroda, and Shigeo Murata; title: 8. Proteasome-interacting proteins / Jean E. O'Donoghue and Colin Gordon; title: 9. Structural studies of large, self-compartmentalizing proteases / Beate Rockel, Jürgen Bosch, and Wolfgang Baumeister; title: 10. What the archaeal PAN - proteasome complex and bacterial ATP-dependent proteases can teach us about the 26S proteasome / Nadia Benaroudj, David Smith, and Alfred L. Goldberg; title: 11. Biochemical functions of ubiquitin and ubiquitin-like protein conjugation / Mark Hochstrasser.