Preformulation solid dosage form development
By: edited by Moji C. Adeyeye, Harry G. Brittain.
Contributors: Adeyeye, Moji C.; Brittain, H. G.
Series: Drugs and the pharmaceutical sciences -- 178
Publisher: Informa Healthcare USA
Published: 2008
Place of publication: New York
Language: eng
Number of pages: 596
ISBN-13: 9780824758097
Subjects: Solid dosage forms; Drug development; Pharmaceutical chemistry; Chemistry, Pharmaceutical; Dosage Forms; Pharmaceutical Preparations -- chemical synthesis
Notes: Includes bibliographical references and index.
Table of contents: title: Accelerating the course of preliminary-preformulation through prediction of molecular physical properties and integrated analytical data management / Robert S. DeWitte, Michel Hachey, and Harry G. Brittain; title: Prediction of crystallographic characteristics / Steve Spanton; title: Salt selection for pharmaceutical compounds / Sherif I. Badawy, Miriam K. Franchini, and Munir A. Hussain; title: Intelligent preformulation design and predictions using artificial neural networks / Nkere K. Ebube; title: Developing a profile of the active pharmaceutical ingredient / Harry G. Brittain; title: Particle morphology and characterization in preformulation / Alan Rawle; title: Preparation and identification of polymorphs and solvatomorphs / Harry G. Brittain; title: X-ray diffraction methods for the characterization of solid pharmaceutical materials / Jean Blachere and Harry G. Brittain; title: Spectroscopic methods for the characterization of drug substances / Harry G. Brittain; title: Thermal analysis and calorimetric methods for the characterization of new crystal forms / Dennette Murphy Shelley Rabel; title: Solubility methods for the characterization of new crystal forms / Harry G. Brittain; title: Overview of the solid dosage form preformulation program / Harry G. Brittain; title: Drug-excipient interactions appropriate to solid dosage forms / Moji Christianah Adeyeye; title: Methods for the determination of the physical and chemical stability of a new solid dosage form / Harry G. Brittain; title: Dissolution testing / Chuck Collins and George Wong; title: Structure, content, and format of the preformulation report / Ram N. Gidwani; title: Significance of drug substance physicochemical properties in regulatory quality by design / Sau Lawrence Lee, Andre S. Raw, and Lawrence Yu.