Serotonin receptor technologies
By: edited by Wolfgang Blenau, Universität zu Köln, Köln, Germany, Arnd Baumann, Forschungszentrum Jülich, Jülich, Germany
Series: Neuromethods -- 95; Springer protocols; Neuromethods -- 95.; Springer protocols (Series)
Publisher: Humana Press
Published: 2015
Place of publication: New York
Language: eng
Number of pages: 245
ISBN-13: 9781493921867; 9781493921874
Subjects: Serotonin Plasma Membrane Transport Proteins; Laboratory Manuals; Signal Transduction; Serotonin; Serotonin Receptors; Laboratory manuals; Metabolism; Neurotransmitter receptors
Description: Reflecting a vast amount of new information concerning the functional characteristics of the various 5-HT receptor subtypes and the Na+-dependent serotonin transporter (SERT), this volume provides state of the art methodologies currently applied in serotonin research from leading experts in the field. Serotonin Receptor Technologies describes approaches that vary from molecular biological and biochemical techniques (e.g., regarding receptor dimerization), fluorescence microscopy and imaging applications, flow cytometry, the use of organotypic slice and cell cultures to the generation of genetically modified animal models and the development of sophisticated behavioral tests, thus covering a wide spectrum of techniques to study serotonergic signaling in detail. Written for the popular Neuromethods series, chapters include the kind of detail and practical advice that ensures successful results in the lab. Authoritative and convenient, Serotonin Receptor Technologies serves to foster both basic and translational research aiming to further deepen our understanding of the various facets of aminergic systems, as well as to aid research on similar problems with related GPCRs and neurotransmitter transporters. --
Notes: Includes bibliographical references and index.