New multi-segment Hill's three-element models for cardiac muscle.
Published: 2006
Language: eng
Number of pages: 78
ISBN-13: 9780494212974
Description: This thesis proposes a new series-connected multi-segment Hill's three-element model for cardiac muscle and furthermore develops a new model with mass considered to incorporate the influence of the inertia. Based on the new multi-segment three-element model, algorithms are developed for isometric and isotonic contraction. Results of numerical simulations show time delay of the tension and length in isometric case and isotonic case respectively, and length variation of each segment as well as the tension change with the number of the segments used due to activation signal transfer. The time delay phenomenon reflects the biological characteristics of cardiac muscles, which cannot be captured by the traditional Hill's three-element model. Furthermore, for the new model with mass, simulation results show that the increase of mass delays the occurrence of maximum tension in the isometric contraction as well as the occurrence of maximum length shortening in the isotonic contraction.
Notes: Source: Masters Abstracts International, Volume: 45-03, page: 1560.

Thesis (M.A.Sc.)--University of Toronto, 2006.

Electronic version licensed for access by U. of T. users.

ROBARTS MICROTEXT copy on microfiche.