The Innate Immune Response to Infection
Contributors: Stefan H. E. Kaufmann (Editor); Ruslan Medzhitov (Editor); Siamon Gordon (Editor)
Publisher: ASM Press
Published: July 30, 2004
Language: eng
Format: Hardcover
Number of pages: 465
ISBN-13: 9781555812911
Subjects: Natural immunity; Medical; Immunity, Natural; Medical / Nursing; physiology; Bacterial Infections; Infectious Diseases; Immunology
First sentence: The foundations of the present concepts of innate and adaptive immunity were established during the latter decades of the 19th century when Metchnikoff (1905) observed phagocytosis in an echinoderm and in an arthropod and Ehrlich (1900) was carrying out pioneering studies on the properties of the specific serum molecules called antibodies.
Description: Delivers a state-of-the-art review of the innate immune system, utilizing the most current concepts of cellular and molecular biology. The book focuses on evolutionary aspects, describing the major cells, humoral factors, receptors, and effector responses central to innate immunity and its important relation to acquired immunity. In-depth treatment is given to the performance of the innate immune system in various situations, including bacterial, viral, fungal, and parasitic infection.