Novel regulation of microRNA biogenesis and function
Contributors: Novina, Carl D.; Chowdhury, Dipanjan; Jacks, Tyler; Vasudevan, Shobha; Buratowski, Steve
Published: 2012
Language: eng
Description: MicroRNAs are small noncoding RNAs that post-transcriptionally reduce protein output from most human mRNAs by mechanisms that are still obscure. This thesis provides insights into three aspects of microRNA biogenesis and function described below.
Notes: Keywords: Akt kinase, Argonaute, microprocessing, microRNA, ribosomal protein, translational repression.

Thesis Ph.D. Harvard University 2012