DNA repair in cancer therapy
By: edited by Lawrence C. Panasci and Moulay A. Alaoui-Jamali.
Contributors: Panasci, Lawrence C.; Alaoui-Jamali, Moulay A.
Series: Cancer drug discovery and development
Publisher: Humana Press
Published: 2004
Place of publication: Totowa, N.J
Language: eng
Number of pages: 362
Subjects: DNA Repair; Neoplasms -- drug therapy; Neoplasms -- genetics
Description: This volume is concerned with the hallmark "relapse" or "drug resistance" phenomena that face the practicing oncologist on a daily basis and it serves as a translational reference for clinical applications. It covers the increasing evidence that impaired expression/activity of at least some of the DNA repair proteins account for tumor cell resistance to particular therapeutic agents. This book summarizes timely in-depth reviews covering the latest developments that have potential for translational and clinical applications and represents the first volume dedicated to the translational aspect of DNA repair in the clinic.
Notes: Includes bibliographical references and index.