Genetic toxicology
Subtitle: principles and methods
By: edited by James M. Parry and Elizabeth M. Parry
Series: Methods in molecular biology -- 817; Springer protocols; Methods in molecular biology (Clifton, N.J.) -- v. 817.; Springer protocols
Publisher: Humana Press
Published: 2012
Place of publication: New York, NY
Language: eng
Number of pages: 433
ISBN-13: 9781617794209; 9781617794216
Subjects: Mutagenicity Tests; Mutagenicity testing; Laboratory Manuals; Genetic toxicology; Mutagens
Notes: Includes bibliographical references and index.
Table of contents: title: The application of structure-activity relationships to the prediction of the mutagenic activity of chemicals / Philip Judson; title: Bacterial mutagenicity assays : test methods / David Gatehouse; title: The mouse lymphoma assay / Melvyn Lloyd and Darren Kidd; title: Mammalian cell HPRT gene mutation assay : test methods / George E. Johnson; title: The in vitro mammalian chromosome aberration test / Gill Claire; title: The interpretation and analysis of cytogenetic data / Natalie Danford; title: The in vitro micronucleus assay / Ann T. Doherty; title: The in vitro and in vivo comet assays / Brian Burlinson; title: Assessment of DNA interstrand crosslinks using the modified alkaline comet assay / Jian Hong Wu and Nigel J. Jones; title: ³²P-postlabelling for the sensitive detection of DNA adducts / Nigel J. Jones; title: Methods for the detection of DNA adducts / Karen Brown; title: The GADD45a-GFP GreenScreen HC assay / Richard M. Walmsley and Matthew Tate; title: Real-time reverse-transcription polymerase chain reaction : technical considerations for gene expression analysis / Shareen H. Doak and Zoulikha M. Zaïr; title: Cytogenetic in vivo assays in somatic cells / Ann T. Doherty, Adi Baumgartner, and Diana Anderson; title: Cytogenetic methods in human biomonitoring : principles and uses / Raluca A. Mateuca, Ilse Decordier, and Micheline Kirsch-Volders; title: The measurement of induced genetic change in mammalian germ cells / Ilse-Dore Adler, Francesca Pacchierotti, and Antonella Russo; title: Transgenic animal mutation models : a review of the models and how they function / Steve Dean; title: Analysis of genotoxicity data in a regulatory context / Ian de G. Mitchell and David O.F. Skibinski.