Anticancer drug development guide
Subtitle: preclinical screening, clinical trials, and approval
By: edited by Beverly A. Teicher, Paul A. Andrews.
Contributors: Teicher, Beverly A., 1952-; Andrews, Paul A.
Edition: 2nd ed.
Series: Cancer drug discovery and development
Publisher: Humana Press
Published: 2004
Place of publication: Totowa, N.J
Language: eng
Number of pages: 450
Subjects: Antineoplastic agents -- Development.; Antineoplastic Agents -- standards.; Clinical Trials.; Drug Approval.; Drug Design.; Drug Evaluation, Preclinical.
Notes: Includes bibliographical references and index.

Minimum system requirements: Adobe reader 6.0 or later.
Table of contents: title: High-volume screening / Michel Pagä; title: High-throughput screening in industry / Michael D. Boisclair ... [et al.]; title: The NCI human tumor cell line (60-cell) screen: concept, implementation, and applications / Michael R. Boyd; title: Human tumor screening / Axel-R. Hanauske, Susan G. Hilsenbeck, and Daniel D. Von Hoff; title: Murine L1210 and P388 leukemias / William R. Waud; title: In vivo methods for screening and preclinical testing: use of rodent solid tumors for drug discovery / Thomas Corbett ... [et al.]; title: Human tumor xenograft models in NCI drug development / Michael C. Alley ... [et al.]; title: Specialized in vitro/in vivo procedures employed by the NCI in preclinical drug evaluations / Melinda G. Hollingshead ... [et al.]; title: Patient-like orthotopic metastatic models of human cancer / Robert M. Hoffman; title: Preclinical models for combination therapy / Beverly A. Teicher; title: Models for biomarkers and minimal residual tumor / Beverly A. Teicher; title: Spontaneously occurring tumors in companion animals as models for drug development / David M. Vail and Douglas H. Thamm; title: Nonclinical testing: from theory to practice / Denis Roy and Paul A. Andrews; title: Nonclinical testing for oncology drug products / Paul A. Andrews and Denis Roy; title: Nonclinical testing for oncology biologic products / Carolyn M. Laurenìot, Denis Roy, and Paul A. Andrews; title: Working with the national cancer institute / Paul Thambi and Edward A. Sausville; title: Phase I trial design and methodology for anticancer drugs / Patrick V. Acevedo, Deborah L. Toppmeyer, and Eric H. Rubin; title: Phase II trials: conventional design and novel strategies in the era of targeted therapies / Keith T. Flaherty and Peter J. O'Dwyer; title: Drug development in Europe: the academic perspective / Chris Twelves ... [et al.]; title: The phase III clinical cancer trial / Ramzi N. Dagher and Richard Pazdur; title: Assessing tumor-related symptoms and health-related quality of life in cancer clinical trials: a regulatory perspective / Judy H. Chiao, Grant Williams, and Donna Griebel; title: The role of the oncology drug advisory committee in the FDA review process for oncologic products / Leslie A. Vaccari; title: FDA role in cancer drug development and requirements for approval / Susan Flamm Honig.