The molecular basis of autism
By: S. Hossein Fatemi, editor
Series: Contemporary clinical neuroscience; Contemporary clinical neuroscience
Publisher: Springer
Published: 2015
Place of publication: New York
Language: eng
Number of pages: 437
ISBN-13: 9781493921898; 9781493921904
Copyright date: 2015
Subjects: Genetics; Molecular aspects; Autism spectrum disorders; Autistic Disorder; Metabolism; Brain Chemistry; Research; Autism
Description: "This book is a comprehensive overview of the clinical and scientific aspects of Autism from the leading experts in the field. The clinical section covers everything from epidemiological features to epigenetic regulation to behavioral therapies and much in between. The basic science section presents the latest knowledge on the underlying causes of the disorder including the role of various neurotransmitters, neurexins and neuroligins, reelin, and other proteins. Chapters also explore the cognition and motor control in autism and the connection between oxidative stress and mitochondrial dysfunction and autism. The thorough description of these underlying causes may help researchers and clinicians find more effective treatments and therapies for the 1 in 68 American children who have been diagnosed with Autism"--Back cover.
Notes: Includes bibliographical references and index.
Table of contents: title: A brief history of autism  -- Fred R. Volkmar; title: Autism spectrum disorder : diagnostic considerations  -- George R. Realmuto; title: Epidemiologic features of autism spectrum disorders  -- R.S. Kirby; title: Genetics of autism spectrum disorders : the opportunity and challenge in the genetics clinic  -- Yi Wang, Ping Wang, Xiu Xu, Jennifer Goldstein, Allyn McConkie, Sau W. Cheung and Yong-hui Jiang; title: Epigenetic regulation in autism  -- Cyril J. Peter, Abraham Reichenberg and Schahram Akbarian; title: Immunology of autism  -- Destanie R. Rose and Paul Ashwood; title: Neuroimaging in autism spectrum disorders  -- Danielle Baribeau and Evdokia Anagnostou; title: The neuropathology of autism  -- Manuel F. Casanova; title: Pharmacology of autism spectrum disorder  -- Donald E. Greydanus, Gabriel Kaplan and Dilip R. Patel; title: Behavioral therapies  -- V. Mark Durand; title: Autism and dopamine  -- Guy Mittleman and Charles D. Blaha; title: Autism and glutamate  -- Maria L. Carlsson; title: Serotonin in autism spectrum disorder : insights from human studies and animal models  -- Natalia Benza and Diane C. Chugani; title: Oxytocin and vasopressin in autism and genetic syndromes  -- Tal Levin-Decanini, Sunday M. Francis, Angela Sagar, Wensheng Liu, C. Sue Carter and Suma Jacob; title: Molecular basis of cholinergic changes in autistic spectrum disorders and relevance for treatment interventions  -- Elizabeta B. Mukaetova-Ladinska and Elaine K. Perry; title: Reelin, GABA, FMRP, and autism  -- Timothy D. Folsom and S. Hossein Fatemi; title: The role of neurexins and neuroligins in autism  -- Amy C. Reichelt and James Dachtler; title: Neurotrophins, their receptors and autism : ligand vs. receptor abnormalities  -- Elizabeth M. Sajdel-Sulkowska; title: Cognition, motor control and other aspects of autism : a pragmatic review  -- James W. Howell and Detlef H. Heck; title: Increased vulnerability to oxidative stress and mitochondrial dysfunction in autism -- Abha Chauhan and Ved Chauhan.