Solar and ultraviolet radiation.
Contributors: World Health Organization.; International Agency for Research on Cancer.
Series: IARC monographs on the evaluation of carcinogenic risks to humans,; v. 55; IARC monographs on the evaluation of carcinogenic risks to humans.; 55
Publisher: IARC; Distributed for the International Agency for Research on Cancer by the Secretariat of the World Health Organization
Published: 1992
Place of publication: Lyon; [Geneva, Switzerland]
Language: eng
Number of pages: 316
Subjects: Radiation carcinogenesis.; Nonionizing radiation.; Radiation, Non-Ionizing
Description: Evaluates carcinogenic risks associated with human exposure to solar radiation and to ultraviolet radiation from medical and cosmetic devices, general illumination, and industrial sources. The main objective of the evaluation was to determine whether enough evidence is available to decide which segments of the radiation spectrum are responsible for its adverse effects. To this end, particular attention is given to data that shed light on the distinctive carcinogenic activity of ultraviolet A, B, and C radiation. In evaluating carcinogenic potential, the report also considers the importance of human constitutional risk factors, such as skin type, hair and eye colour, and specific subtypes of exposure, such as occupational and recreational exposures. More than 1,000 studies were critically assessed. On the basis of a large body of evidence from human and experimental studies, the monograph concludes that solar radiation is carcino-genic to humans, causing cutaneous malignant melanoma and nonmelanocytic skin cancer. Evidence for the carcinogenicity of ultraviolet A, B, and C radiation was judged sufficient in experimental animals. All three segments of the radiation spectrum were classified as probably carcinogenic to humans. Use of sunlamps and sunbeds entails exposures that are probably carcinogenic to humans. The carcinogenicity of exposure to fluorescent lighting could not be determined. Studies of topical sunscreens are reviewed in an appendix, which concludes that, although effective in preventing sunburn, little is known about their protective value against harmful immuno-logical changes, photo-ageing, or skin cancer.
Notes: Includes bibliographical references (p. 229-279) and index.
"The views and expert opinions of an IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, which met in Lyon, 11-18 February 1992."