Introduction to Macromolecular Binding Equilibria
Edition: 1 edition
Publisher: CRC
Published: November 8, 2007
Language: eng
Format: Hardcover
Number of pages: 272
ISBN-13: 9781420052985
Subjects: Biophysics; Science; Science/Mathematics; Life Sciences - Biochemistry; Physics; Science / Physics; Chemistry - Physical & Theoretical; Binding sites (Biochemistry); Ligand binding (Biochemistry); Macromolecules
Description: "Introduction to Macromolecular Binding Equilibria gives students in medicinal chemistry, pharmaceuticals, and bioengineering the necessary background in biophysical chemistry for research applications in drug discovery and development. Building upon a fundamental knowledge of calculus and physical chemistry, this compact, graduate-level text prepares students for advanced work in solution thermodynamics and binding phenomena and applying methods in this book to their own research." "This book describes the underlying theory of binding phenomena and explains how to apply the binding polynomial approach for building models and interpreting data. It also covers practical considerations for setting up binding experiments and describes how to obtain true thermodynamic isotherms unbiased by model assumption via model-free analysis of binding data."--BOOK JACKET.