Techniques in epidermal biology
Subtitle: an integrated approach to autoimmune skin disease
By: Nicola Cirillo
Publisher: Nova Science Publishers
Published: 2011
Place of publication: Hauppauge, N.Y
Language: eng
ISBN-13: 9781612096216
Subjects: Pathophysiology; Epidermolysis bullosa; Pemphigus; Acantholysis
Notes: Includes bibliographical references and index.
Table of contents: title: Current knowledge on pemphigus pathophysiology; title: Patients, sera, and experimental models; title: Optimization of the experimental procedures : semi-quantitative LCIF microscopy, C-HSU buffer, and KAD medium; title: Study of anti-desmoglein autoimmunity : pemphigus as a desmoglein-remodeling disease; title: Role on non-desmoglein and non-igg in pemphigus; title: Downstream signaling involved in acantholysis : I. changes in cell cycle and protein phosphorylation; title: Downstream signaling involved in acantholysis : II. secretion of proteinases and the specific proteolysis hypothesis of pemphigus; title: Microarray analysis of diseased tissues : cell adhesion is down-regulated on the gene level in pemphigus; title: Pharmacological block of acantholysis : towards novel therapies for the treatment of pemphigus.