Design of caspase inhibitors as potential clinical agents
By: editor(s), Tom O'Brien, Steven D. Linton.
Contributors: O'Brien, Tom.; Linton, Steven D.
Series: CRC enzyme inhibitors series
Publisher: Taylor & Francis
Published: 2009
Place of publication: Boca Raton
Language: eng
ISBN-13: 9781420045406
Subjects: Cysteine proteinases; Cysteine proteinases -- Inhibitors; Caspases -- antagonists & inhibitors; Apoptosis; Caspases -- physiology; Caspases -- therapeutic use
Notes: Includes bibliographical references and index.
Table of contents: title: Mammalian caspase activation pathways in apoptosis and inflammation / Susan Logue and Seamus Martin; title: Role of caspases in inflammatory diseases / Kristof Kersse ... [et al.]; title: Role of caspases in apoptotic-driven indications / Takashi Matsui; title: Kinetics and catalytic activity of caspases / Kip Nalley; title: Non-peptide small molecule inhibitors of caspases / Alexandre Ivachtchenko ... [et al.]; title: Identification of inflammatory caspase inhibitors / John Wos and Thomas Demuth Jr; title: Identification of apoptotic caspase inhibitors / Brett Ullman; title: Discovery of a first-in-class apoptotic caspase inhibitor, emricasan (pf-03491390/idn-6556) / Niel Holgen; title: Novel approaches to caspase inhibitor discovery / Justin Scheer and Michael Romanowski; title: Therapeutic potential for caspase inhibitors : present and future / Hiroyuki Eda.