Pulmonary arterial hypertension
Subtitle: diagnosis and evidence-based treatment
By: edited by Robyn Barst.
Contributors: Barst, Robyn.
Publisher: John Wiley & Sons
Published: 2008
Place of publication: Chichester, West Sussex, England; Hoboken, NJ
Language: eng
Number of pages: 256
ISBN-13: 9780470059722
Subjects: Pulmonary hypertension; Evidence-based medicine; Hypertension, Pulmonary -- diagnosis; Hypertension, Pulmonary -- therapy; Evidence-Based Medicine -- methods; Pulmonary Artery -- pathology
Description: Pulmonary hypertension is frequently misdiagnosed and has often progressed to a late stage by the time it is accurately diagnosed. It has therefore long been considered untreatable and incurable with an overall very poor survival rate. However, new treatments are now available which have significantly improved prognosis. Recent data demonstrate survival is continuing to improve, with patients living for fifteen to twenty years or longer after diagnosis with an overall good quality of life. In this work, each chapter will discuss therapeutic options with reference to the pre-clinical studies which provided the rationale for their clinical development. The book also includes evidence-based treatment algorithms based on the 2007 update of the ACCP Guidelines for Medical Treatment of Pulmonary Hypertension.
Notes: Includes bibliographical references and index.
Table of contents: title: Diagnosis and assessment of pulmonary arterial hypertension / Michael D. McGoon, Adam Torbicki, and Ronald J. Oudiz; title: Conventional therapies / Richard N. Channick; title: Prostanoids in pulmonary arterial hypertension / Olivier Sitbon and Gerald Simonneau; title: Endothelin receptor antagonists in pulmonary arterial hypertension / David B. Badesch and Marc Humbert; title: Phosphodiesterase-5 inhibitors in pulmonary arterial hypertension / Hossein A. Ghofrani, Werner Seeger, and Friedrich Grimminger; title: Combination therapy in pulmonary arterial hypertension / Anne Keogh and Marius Hoeper; title: Interventional and surgical modalities of treatment in pulmonary arterial hypertension / Julio Sandoval and Ramona Doyle; title: End points and clinical trial design in pulmonary arterial hypertension : clinical and regulatory perspectives / Andrew J. Peacock and Christopher M. Carlin; title: Comparative analysis of clinical trials and evidence-based treatment algorithm in pulmonary arterial hypertension / Nazzareno Galie ... [et al.]; title: Diagnosis and assessment of non-pulmonary arterial hypertension masquerading as idiopathic pulmonary arterial hypertension : diastolic heart failure; title: evaluation and interactions / Mardi Gomberg-Maitland and Stuart Rich; title: Treatment of pulmonary arterial hypertension : a look to the future / Lewis J. Rubin.