The Blood-Brain Barrier and Drug Delivery to the CNS
Contributors: Michael Bradbury (Editor); David Begley (Editor); Jorg Kreuter (Editor)
Edition: 1st edition
Publisher: Informa Healthcare; Dekker
Published: May 15, 2000
Language: eng
Format: Hardcover
Number of pages: 248
ISBN-13: 9780824703943
Subjects: Neurology & clinical neurophysiology; Physiology; pharmacokinetics; Pathophysiology; Drug Delivery Systems; Central Nervous System Physiology; Physiological transport; Science; Medical / Nursing; Pain Medicine; Science/Mathematics; Drugs; Pharmacology; Medical / Pharmacology; Blood-brain barrier; Life Sciences - Anatomy & Physiology; Central Nervous System Agents; Congresses
First sentence: Among the factors that influence uptake and distribution of a drug into a tissue or organ outside the central nervous system (CNS) are blood flow, binding to proteins in blood plasma, clearance from blood, and metabolism.