AlgoLab/PIntron — Issue #5: Removing noisy exons
Author: rrizzi
Created: 2011-12-07 11:09:20+00:00
State: open

In the gene ABO, the factorization of RefSeq NM_020469 is composed by 3 exons, while the annotated factorization is composed by 7 exons.
PIntron correctly finds the annotated factorization, but in a post-processing phase it removes the fourth exon, since it has two mismatch errors wrt the corresponding RefSeq factor, but the maximum error allowed in this case is only one (the 3% of the exon length but not less than 1). After removing the fourth exon, PIntron retains only the last three exons of the annotated factorization.

PIntron version: `v1.2.18`
Source file: est-factorizations.c (see function clean_noisy_exons)