mxcl/homebrew — comment on commit 99b4fd828158891b1d7e30d14c77105413ebf04f
File:  line 0
By ashgti:

pygobject depends on GObject-Introspection, however the python bindings to gobject-introspection do not compile on OS X (last I checked), so `--disable-introspection` disables the python module for using it, but its still needed internally. So, yes that does seem completely wrong, its still required to depend on `object-introspection` and also `--disable-introspection` in order for pygobject to compile. This does mean the `gi` (gobject-introspection) module in the pygobject library does not work on OS X, but the rest of the library should work.