### extremely painful condition | stenosis:

Pyloric stenosis
* congenital defect, or condition present at birth.
* is much more common in boys than girls
  - treated by a minor surgical procedure
* narrowing of the pylorus
  - stomach's outlet, which is called the pylorus

### extremely painful condition | stenosis:

Spinal stenosis
* can also cause compressive type pain
  - be difficult to treat definitively without surgery
  - cause a wide variety of symptoms throughout the body
* disease affecting the nerves exiting the spinal canal.
* is an often overlooked cause of back and leg pain
  - most often the result of the progressive wear and tear associated with age
  - the thickening of bone around the spinal canal
* narrowing of the canal in the vertebrae that surround the spinal cord
  - spinal canal that produces compression of the neural elements
* occurs in middle-aged or elderly people
  - when the spinal canal or nerve root canals become too narrow

Subglottic stenosis
* can be congenital or acquired.
* narrowing of the airway below the vocal folds.

### extremely powerful substances:

Human hormone
* Most human hormones play roles
  - vital roles
* Most human hormones provide benefits
  - other benefits
* are extremely powerful substances.

### extremely rapid:

Renal excretion
* Some renal excretion causes accumulation
  - drug accumulation
  - is produced by adults
* equals intestinal absorption.
* is extremely rapid.
* is the predominant route of elimination
  - preferred route of elimination in man, baboon and mouse
* occurs by glomerular filtration and active tubular secretion.

### extremely rare:

Human infection
* Many human infections are mild and inapparent and thus go undetected.
* Most human infection is associated with an uncomplicated febrile illness or is inapparent.
* Most human infections are actually quite mild with a fever, headache, and body aches
  - asymptomatic or present as a nonspecific viral syndrome
  - mild enough to go unnoticed and apparently produce no permanent damage
  - silent
  - result from the consumption of improperly cooked or contaminated foodstuffs
* Some human infection occurs in infants.
* are extremely rare.
* are most common in Asia, Africa, Latin and South America and the Middle East
  - the Orient, Africa, South America, or the Middle East
  - quite common in Canada and most other parts of the world
  - rare and usually occur when people inadvertently consume an infected flea
  - rare, and often mild
* begins with the ingestion of infected raw or undercooked pork.
* can be pneumonia due to the worm migration
  - occur from a bite of a mosquito that has previously bitten an infected bird
* comes from eating raw or insufficiently cooked meat.
* do occur, but are extremely rare.
* is common
  - diagnosed by the parasite eggs in the faeces
  - more common in men than women
  - possible with roundworms if the eggs are ingested
* is usually from pigs and is rare
  - through the skin but has occurred after ingestion of contaminated meat
  - virtually universal - most adults are seropositive
* occur by inhalation of aerosols of infectious excreta.
* occurs by the ingestion of larvae when eating raw or undercooked freshwater fish
  - due to the accidental ingestion of eggs passed in human faeces
  - from breathing dust in the air contaminated by spores
  - in the warm months of the year as ticks become active
  - mainly from the ingestion of raw lamb, pork or beef
  - primarily via inhalation of aerosolized infected rodent excreta
  - when dust containing infected dried rodent excretions is inhaled
  - where raw fish delicacy
* tend to be mild and self limiting, and most probably are never diagnosed.

Malignant degeneration
* is extremely rare
  - very rare in children, but in adults, most die within a year of diagnosis
* occurs more commonly with complete molar pregnancy.

Octahedral crystal
* are extremely rare.
* do occur, but are very rare.