### substance:

Platelet
* Are fragments of cells formed in the bone marrow.
* Some platelets isolate from gingkoes.
* a. are very tiny cells.
* adhere to collagen
  - the damaged area and become cohesive to other platelets
  - torn blood vessels to create a plug, slowing the loss of blood
* aggregate and blood clots in the vessels, reducing blood flow to the graft
  - normally in response to various agonists
* allow the blood to clot, for example, after injury from a cut or scrape.
* also aid in blood clotting, and are needed by cancer patients
  - assure that blood vessels stay leakproof in daily life
  - contribute to the immune response
  - help to promote other blood clotting mechanisms
  - play a critical role in the healing process and promote blood clotting
  - secrete chemicals that stimulate immune system function
* apparently mistake the bacterial substance for collagen.
* appear as highly refractile particles under the high power lens
  - yellow stars
  - degranulated
  - indistinguishable at low magnification from debris on blood smears
* are a blood product that serve as the body's first line of defense against bleeding
  - component in the blood that are essential to normal blood clotting
  - key factor in the body's ability to form blood clots
  - specialized type of blood cell that clump together to prevent bleeding
* are a type of blood cell important to blood clotting
  - cell found in the blood
  - very important component of blood
  - active in blood clotting and they are rich in inflammatory mediators
  - actually fragments of large cells that are present only inbone marrow
  - almost never high enough to cause health problems
  - an important part of the clotting factor in blood
  - blood cells necessary for clotting
* are blood cells that help control bleeding
  - form blood clots and stop bleeding
  - perform a wide variety of functions
  - strengthen blood vessel walls and help seal cuts
* are blood components responsible for a person's blood clotting
  - cell fragments in the bloodstream that enable blood to clot
* are cell fragments involved in blood
  - with blood clotting
  - responsible for blood clotting
* are cell fragments that bud off megakaryocytes in bone marrow
  - function in blood clotting
  - cells found in blood that help form clots to stop bleeding
* are cells in the blood that are essential to blood clotting
  - help stop bleeding
  - produced by the bone marrow and are responsible for blood clotting
  - central to the process of wound healing
  - clot-forming blood cells which prevent excessive bleeding
  - colorless cells, produced in the bone marrow, that aid in the clotting of blood
  - critical to blood coagulation and the formation of clots to stop bleeding
  - discoid cells of the blood
* are essential for clotting
  - the formation of a blood clot
  - fragments of blood cells that help the blood clot, or form a scab
* are fragments of cells that are less than half the size of red blood cells
  - live in the bone marrow
* are fragments of the cytoplasm of megakaryocytes, another bone marrow cell
  - giant bone-marrow cells called megakaryocytes
  - important for proper blood clotting
  - involved in hemostasis through the making of blood clots
  - like little corks
  - little cell-like blood components which help the blood to clot
  - microscopic cell fragments whose main function is to help blood clot
  - minute colourless cells
  - much smaller in size than the other blood cells
* are necessary for blood clotting
* are one component involved in clotting blood
  - of the components of blood that help blood to clot
* are particles in the blood the assist in clotting
  - involved in the blood clotting process
* are particles that circulate in the blood and play a role in clotting
* are produced in bone marrow by a process known as thrombopoiesis
  - the bone marrow and are involved in the process of making a blood clot
  - really 'thrombocytes'
  - repsosnsible for blood clotting
* are responsible for causing damage to the cells that line the inside of the blood vessels
* are responsible for helping the blood to clot and prevent bleeding
  - to clot in order to prevent bleeding
* are small Blood cells that help control bleeding
  - cells circulating in the blood
* are small cells in the blood responsible for blood clotting
  - that help clot the blood
* are small cells that are found in the peripheral blood
  - float around in our blood stream
  - which are needed for blood to clot normally
  - disc shaped cells that are formed in the bone marrow
  - disk-shaped blood cells that clump together to form blood clots
  - elements of the blood that can clump together and initiate blood clot formation
  - fragments of cells, with no nucleus
  - specialized blood cells that help prevent and stop bleeding
  - sticky cells that help control bleeding
* are the agents in the blood that cause clotting
  - blood component that is one of the steps necessary for clotting
  - blood's main clotting agent
  - cells in blood that cause it to clot
* are the clotting agents in the bloodstream
  - factors in blood that are the number one trigger of heart attacks
* are the component of blood that cause clotting
  - controls bleeding
  - components of blood that stop bleeding
  - constituent in blood that helps it clot
  - disc shaped cells that stop bleeding
  - first line of defense against vascular injury
  - major blood-clotting elements of the body
  - primary source of amyloid b peptide in human blood
* are the smallest cells in the blood and are essential to blood coagulation
  - human blood cell and are essential for wound healing
  - normal cellular element seen in blood smears
  - special cells that clump together and control bleeding after an injury
  - tiny cells that seal minor cuts and wounds and form blood clots
  - there to help the blood clot
  - tiny blood cells formed in the bone marrow
* are tiny blood cells that are essential for blood to clot normally
  - function to help prevent and stop bleeding
  - bodies that are much smaller than red blood cells
  - cells that help blood to clot
  - disk-shaped bodies that help stop bleeding when blood vessels are damaged
  - particles in the blood that form a mesh in an early stage of blood clotting
  - unique in that they have a short life span of just five days
* are very delicate, enable cuts to heal and only last for five days
  - large when they are first made
  - small fragments of cells
* are what allow blood to clot after surgery or some type of trauma
  - is responsible for the clotting
  - make blood clot
  - yellow, disc shaped cells that help the blood to clot
* arrive at the site of a rupture of a blood vessel and initially plug the leak.
* attach to the atheroma.
* become activated and adhere to endothelium and leukocytes.
* can elevate as acute phase reactants.
* cause clotting when cuts or other open wounds occur.
* circulate in the blood and are important in blood clotting
  - play a vital role in the control of bleeding
  - as resting cells in the shape of discs
* clump around the area of injury as a normal part of the clotting and healing process
  - wound forming a clot, which blocks blood flow to the heart
* coagulate blood and prevent excessive bleeding.
* collect in an attempt to stop bleeding.
* contain clotting factors that plug up blood vessel walls when they are torn
  - many chemicals that assist clotting
  - secretory granules
* control bleeding and induce clotting.
* control bleeding by attaching to an injured surface and forming a clot
  - helping repair injured blood vessels
  - in patients with leukemia and other illnesses
* form a 'mesh' net to form clots in the Blood to help stop bleeding
  - platelet plug to stop bleeding
  - wreath around a segmented neutrophil
  - from the breaking apart of the cytoplasm of the fully mature megakaryocytes
* function in the clotting of blood.
* have a limited life span before they are replaced by new platelets.
* have a short life-span of just five days
  - only five days
  - ofjust five days
  - the shortest shelf-life and can be stored for only about five days
* help blood clot and prevent bleeding
  - clot blood when there break in a blood vessel, such as a cut in the skin
  - control bleeding by covering blood vessels opened by injury or surgery
* help in the clotting of blood
  - formation of blood clots
  - speed clotting time, and platelets help fight shock
* help stop bleeding by plugging leaks in blood vessels
* immediately form a plug at the site of injury.
* initiate a chain of reactions that lead to blood clotting.
* is granule of granule.
* lack dense granules and platelet function is abnormal.
* live a few weeks and are constantly being produced by the bone marrow.
* make the blood clot.
* play a big part in stopping bleeding.
* play a crucial part in the blood clotting process by forming a platelet plug
  - role in helping blood to clot
  - major role in blood clotting as described in the next section
* play a role in blood clot formation
  - coagulation and wound healing
  - the patient from bleeding to death
* probably play little if any role in the pathogenesis of multiple sclerosis.
* promote blood clotting and repair gaps in the walls of blood vessels.
* promote clotting in blood
  - of the blood, and prevent excessive bleeding
* release chemicals that are needed for blood clotting
  - clotting factors, which begin a series of reactions to produce fibrin
  - substances that help blood clot
* rush to the point of injury to stop the bleeding.
* send out filopodia that entangle each other.
* stick together to stop bleeding.
* then activate substances in plasma which form a clot and allow the wound to heal.
* undergo changes in configuration and release reactions.
* work with other substances to form clots where blood vessels are but.
+ Blood, Platelets: Biochemistry :: Cardiovascular system
  * Platelets help make blood clot. A clot is when the liquid blood becomes solid. The body makes blood clot when the skin is cut. This stops blood from going out of the skin too much.
  * Platelet-helps heal wounds. Platelets are really 'thrombocytes'. The platelets take part in blood clots when injury occurs. Blood tissues are also known as vascular tissue.
  * A 'platelet' is a cell fragment that circulates in the blood. Platelets are involved in hemostasis through the making of blood clots.
+ Clot, The details
  * Coagulation begins almost instantly after an injury to the blood vessel has damaged the endothelium lining the vessel. When blood is exposed to proteins such as tissue factor it starts changes to blood platelets and the plasma protein fibrinogen, which is a clotting factor. Platelets immediately form a plug at the site of injury. Proteins in the blood plasma, called 'coagulation factors' or 'clotting factors', respond in a complex cascade to form fibrin strands. These strengthen the platelet plug.