### substance | corpuscle:

Eosinophil
* accumulate in the lung parenchyma.
* adhere to and stimulate replication of lung fibroblasts in vitro.
* are a particular kind of white blood cells
  - type of white blood cell that increases in number during an allergic reaction
  - about the same size as neutrophils, but have reddish-orange granules
  - also motile and phagocytic, and migrate into the tissues
  - another cell commonly present in inflammation
  - chemotoxic and kill parasites
  - common, especially in early lesions
  - cytotoxic, releasing the contents of their granules on the invader
  - few to absent
* are granulocytes that play a role in defending against parasitic worms
  - which can stain intensely with the dye eosin
  - motile and phagocytic and are particularly active in parasitic infection
  - much less common than neutrophils
* are one of the blood components measured in a routine blood count
  - predominant
  - present in some instances, but neutrophils usually predominate
  - recognized by their granules that stain red
  - round cells with a lobed nucleus and granules which turn red when stained
  - the most poorly understood of the pro-inflammatory leukocytes
* are white blood cells that participate in immunologic and allergic events
  - used for specific purposes
* attack protozoa that cause infection.
* can also phagocytose and digest antigen-antibody complexes
  - increase with allergic reactions and with parasitic infestations
* cause acute edematous injury in isolated perfused rat lungs.
* come out of the bone marrow, enter the blood, and make their way to the airways.
* congregate particularly at sites of allergic and parasitic reactions.
* disappear with corticosteroids.
* enhance the immune response to helminths.
* express a functional receptor for interferon alpha.
* increase in tissue in response to both allergy and parasites.
* invade the airways in response to an insult, such as exposure to an allergen.
* kill parasites, destroy cancer cells, and are involved in allergic responses.
* often occur in hypersensitivity reactions and in association with parasitic infections.
* participate in protective reactions to certain parasites
  - the immune defense of the lung
* perform an immunosuppressive function in immediate hypersensitivity reactions.
* release major basic protein which is damaging to cells.
* secrete enzymes that punch holes in parasitic worms.
* then release toxic substances that can kill parasites and destroy abnormal human cells.
* typically have a bilobate nucleus separated by a thin filament.
+ Pneumonia, Other types of pneumonia: Infectious diseases :: Pulmonology
  * Eosinophilic pneumonia is invasion of the lung by 'eosinophils'. Eosinophils are a particular kind of white blood cells. Eosinophilic pneumonia often occurs in response to infection with a parasite or after exposure to certain types of environmental factors.
+ White blood cell, Types of white blood cells, Granulocytes, Eosinophils: Cell biology :: Immunology :: Blood cells
  * Eosinophils, or 'acidophils', are leukocytes. They are one of the immune system components which combat parasites and certain infections. As with mast cells and basophils, they part causes of allergy and asthma. Eosinophils are round cells with a lobed nucleus and granules which turn red when stained. These granules are packed with proteins that can be poured out to help destroy invaders.