### alteration | damage:

Liver damage
* Some liver damage is caused by fireweeds
  - worms
* appears to be the result of increased liver cell death.
  - be a side effect of intravenous feeding
  - continue for months, but as patients improve, the cytokine levels decrease
  - impair lipid digestion and cause cardiovascular portal hypertension
* can occur at higher doses
  - unnoticed especially in children who experiment with drugs
* is also evident when liver enzymes are measured following heatstroke
  - an important objective measure of the consequences of excessive alcohol drinking
  - common in people who are regular, illegal drug users
  - something that progresses over the years and is usually permanent
* major side effect of chronic steroid abuse by athletes.
* occurs infrequently, and is usually reversible.
* rare side effect of anti-androgens
  - the drug
* widely known consequence of alcohol abuse.

Mechanical damage
* increases the extent to which the fruit can be infected by fungi.
* is one of the leading causes of injury and death of landscape plants.
* occurs as a result of weather events and human activities
  - during harvesting and grain handling
  - when flowers are handled poorly or overpacked

Muscle damage
* Some muscle damage is caused by workouts.
* can occur during rectal surgery.
* is involved in most cases of fecal incontinence.
* leads to health problems
  - serious problems
* occurs when myofibers experience mechanical stress.

Nematode damage
* Some nematode damage occurs in irregularly shape patches
* appears as weak areas invaded by weeds.
* can also occur as twig dieback, excessive leaf drop, or bronze foliage.
* is countered by adding manure to the soil and replanting damaged areas
  - greater on plants stressed by other factors
  - more severe in sandy soils than in heavy soils
  - visible as stunted yellowed plants

### alteration | damage:

Nerve damage
* Some nerve damage is caused by diabetes.
* associated with the birth defect spina bifida can also cause incontinence
  - bifida can cause incontinence
* can affect many parts of the body
  - the heart, eyes, kidneys, sexual organs, legs and feet
* can also affect hearing and cause deafness
  - be a cause, especially of cold feet
  - cause a slow emptying of the stomach known as gastric stasis
* can also cause problems with eating, going to the bathroom, or having sex
  - internal organs
* can also lead to a gradual loss of sexual response
  - deformities of the feet and toes
  - limit blood flow
* can cause impotence in men
  - the stomach to empty too slowly a disorder called gastric stasis
* can occur from a lifetime of overdrinking or even from a single drunken binge
  - in the same way and impact on sexual arousal as well
* caused by poor circulation leads to a loss of feeling in the feet.
* causes a loss of normal skin moisture
  - other people with diabetes constant pain in their limbs
* common cause of impotence in men who have had spinal cord injuries.
* has many possible causes, such as diabetes and vitamin deficiencies.
* is indicated if the nerve conduction is slower than normal
  - so common in diabetics and in alcoholics
  - suspected when any symptoms occur regularly during the day
  - the most common form of hearing loss
* leads to a loss of sensation, and ultimately to paralysis
* means non-recognition by the patient that a disease process or injury is occurring.
* occurs in people who have had diabetes for a long time
  - over the course of years
* prime example, with blood flow restricted to a specific part of the body.
* resulting from implants can lead to permanent numbness in the lower lip and chin.
* serious complication of diabetes.

Neurological damage
* Most neurological damage includes deterioration
  - leads to conditions
* can be evident long after the parasites leave the kidneys
  - severe and is irreversible
  - show up in some children as learning difficulties and behavioral problems