### physical process | biological process:

Metastasis
* Metastases are nodules of cancer away from the primary site
  - that have moved away from the primary or initial site
  - present in two-thirds of patients at the time of presentation
  - rare, and tumor-related deaths are exceptional
  - secondary tumours which have developed away from the original tumour site
  - spread via the bloodstream from tumors in other places in the body
  - usually present at the time of diagnosis
  - can appear in any part of the body
  - first occur in regional nodes and then the liver
  - frequently originate from cancers of the breast or lung, and from melanomas
  - have a variable appearance following gadolinium administration
  - usually consist of the adenocarcinomatous element
* Most metastases are multiple except for kidney which is frequently single.
* is diseases.
* occurs via the bloodstream, or lymph system.
+ Vaginal cancer: Cancer
  * Primary vaginal cancer is rare in the general population of women. Metastases are more common. Vaginal cancer occurs more often in women over age 50, but can occur at any age, even in when they're pregnant. It often can be cured if found and treated in its early stages. Surgery alone or surgery combined with pelvic radiation is typically used to treat vaginal cancer.

### physical process | biological process | metastasis:

Bone metastasis
* Bone metastases are made up of abnormal cancer cells that start from the original tumor site
  - one of the most common causes of morbidity in cancer patients
  - particularly common in people with breast, lung or prostate cancer
  - usually multiple
  - worrisome for several reasons
* Bone metastases can cause a release of calcium into the bloodstream
  - debilitating pain and severe fractures
* is suspected when a patient with lung cancer has new and persistent bone pain.
* refers to a cancer that has spread from the primary site to one site in the bone.

Brain metastasis
* Brain metastases are tumor cells that have traveled through the blood stream to enter the brain
  - tumors that arise from outside of the brain and spread to the brain
* carry a poor prognosis and high morbidity.

Hematogenous metastasis
* Hematogenous metastases can also cavitate.
* requires tumor cell attachment to the vessel wall during blood flow.

Hepatic metastasis
* Hepatic metastases are a major cause of death in patients with disseminated colorectal cancer
  - also common
* is also present and visible.

Liver metastasis
* Liver metastases are more common from primary disease below the diaphragm
  - imply a major problem in patients with carcinoid tumours
* Most liver metastases are asymptomatic and therefore can be extensive prior to diagnosis.
* is one of the major causes of cancer death after resection of pancreatic cancer.

Systemic metastasis
* Systemic metastases are generally hematogenous in origin, and the liver is the most common site.
* occurs in about one-third of patients with subcutaneous involvement.

Neoplasia
* is an abnormal growth in the number of cells
  - characterized by genetic instability
  - common in older cats
  - the primary manifestation of some cancer genes, such as the retinoblastoma gene
* means a new abnormal growth of cells
  - new growth
  - the new development of abnormal cells
* publishes the results of novel investigations in all areas of oncology research.

### physical process | biological process:

Ontogeny
* constrains the systemic protease inhibitor response in Nicotiana attenuata.
* follows phylogeny.
* is another name for embryonic development
  - variability which has gone to extremes in skates
  - the study of the development of an adult organism from a single-celled zygote
  - thus the developmental process of a multicellular organism
* recapitualtes phylogeny.
* recapitulates phylogeny, as the psychoanalyists say.
* recaptulates phylogeny, in interactive media as in biological media.