### drug:

Cocaine
* CAN cause sudden death in otherwise healthy young people - even once can be fatal.
* Most cocaine is used as an illegal drug
  * is white and is made up of small crystals. Most cocaine is used as an illegal drug. Because it stimulant, cocaine makes people feel very happy and energetic when it is eaten, smoked, or inhaled. When used this way, cocaine is very addictive. Because of this, doctors and dentists sometimes use cocaine as a legal drug
* abusing mothers are at a greater risk for miscarriage and premature delivery.
* acts as a dopaminergic agonist, supersensitizing dopamine neurons
  - stimulant , whereas heroin acts as a depressant
  - on nerves in the pathway that produce the neurotransmitter dopamine
* affects the dopaminergic, serotonergic, and neuroepinepherine systems
  - membranes of the openings to the lungs causing mucous to form and inflammation
* also activates the mesocortical and mesolimbic dopaminergic pathways
  - can induce premature labor
* also causes a strong psychological dependence
  - acute pulmonary edema, usually when used as free-base cocaine
  - fibrillation of the heart and strokes form uncontrolled blood pressure
* appears as a white powder substance which comes from coca leaves or is made synthetically
  - in several forms, including powder, free-base, crack or rock
* appears to be a drug with two different faces, depending on the method of use
  - do less for a woman's sexual functioning than it does for a man's
* back-room drug.
* belongs to a class of drugs known as stimulants, which give a fleeting feeling of energy
  - the group of drugs known as stimulants
* benzoic acid ester.
* blocks the recycling of of dopamine and norepinephrine transmitters in the brain.
* can also affect the peripheral nervous system.
* can also cause disturbances in the rhythm of the heart beat
  - severe deformities in a fetus
  - heighten irritability, excitability, and startle response
  - induce paranoia and violent behaviour
  - lead to compulsive use or dependence
  - send coronary arteries into spasm
* can be a powerful trigger for cardiac arrest
  - very addictive drug
* can be extremely dangerous when used in combination with other drugs
  - harmful to the hearing and can cause death
* can become addicting to a some of people who use it
  - cause euphoria and increased confidence
* can cause heart attacks and strokes in young people
  - problems, convulsions and paranoia
  - loss of concentration, irritability, and a loss of memory
  - lung damage in a very short time
  - seizures
  - serious damage to the central nervous system and sudden heart attacks
  - constrict heart arteries so profoundly that no blood gets to the heart muscle
  - easily spread to money, which changes hands quickly
  - have a great variety of other effects on the nervous system of a person who uses it
  - induce a stroke in the fetus and can cause spontaneous abortion
  - kill instantly by restricting the flow of blood to the brain and heart
* can lead to feelings of euphoria
  - great physical strength and mental capacity
  - several effects in the nose and sinuses
  - make the heart beat irregularly and increases body temperature
  - produce psychological and physical dependency
  - temporarily reduce the amount of oxygen being supplied to an area of the heart muscle
* causes a sense of energy, alertness, talktiveness, and well-being users find pleasurable
  - an unmistakable euphoria and sense of well-being that is the basis of addiction
  - blood vessels to constrict, reducing the flow of blood to the brain
  - intense spasms of the arteries of the heart, depriving the heart of oxygen
  - profound loss of appetite, leading to severe weight loss and nutritional imbalance
  - psychological and physiological changes
  - strokes and heart attacks
  - strong physical dependence
* central nervous system stimulant, the most powerful found in nature.
* class A drug, which means it is the best.
* comes as a white powder that is usually snorted up the nose.
* comes from the leaves of the coca plant, which is grown in South America
  - tropical coca plant
* comes in a white crystalline powder
  - many forms
* constricts blood vessels and increase the pulse and blood pressure
  - the blood vessels
* contributes to systemic violence, and alcohol to psychopharmacological violence.
* crosses the placenta by simple diffusion.
* dangerous drug for unborn babies.
* decreases the glycine-induced current in acutely dissociated neurons from rat hippocampus
  - uteroplacental blood flow in the rat
* disturbs the normal sleep cycles of babies.
* does only a few things to the heart that can be dangerous or cause death.
* dramatically changes monoamine- mediated synaptic transmission.
* drug designed for energetic people
  - extracted from the leaves of the coca plant
  - made from the coca plant
* drug made from the leaves of the coca plant, which grows in South America
  - of abuse that produces profound behavioral changes
* drug that is abused terribly and is the source of great misery and death
  - no one can handle safely
  - that's much more geared toward the creative process
* effects all the monoamine neurotransmitters.
* elevates the perceived effect of arousal, both male and female.
* enhances the excitatory action of noradrenaline in the rat dorsal raphe nucleus.
* goes to the tegmental of the brain.
* hard drug
* highly addictive drug that causes physical and psychological dependence.
* increases blood pressure which can lead to irregular heartbeat and death
  - heart rate and blood pressure
  - the heart rate and arteries constrict
* induces elation primarily by blocking the dopamine transporter
  - euphoria, confidence and a sense of increased energy in the user
* inhibits alanine uptake by human placental microvillous membrane vesicles
  - the active reuptake of norepinephrine into presynaptic nerve terminals
* interferes with judgment and produces exaggerated feelings of well-being and confidence
  - testicular function
* is absorbed from all sites of application.
* is addictive and produces a disorder called anhedonia during withdrawal
  - particularly when used in the very short-acting form known as 'crack'
  - substances
  - alkaloids
* is almost as freely available as alcohol and is nearly as popular
  - two drugs in one, blending stimulant and anesthetic effects in a single molecule
* is among the most psychologically and physically addictive of all drugs
  - reinforcing of drugs
  - an addictive drug
* is an addictive substance which comes form coca leaves or is made synthetically
* is an alkaloid drug found in the leaves of the coca plant
  - which is derived from coca leaves, most of which are grown in South America
  - another well-known alkaloid with pharmaceutical use
  - available as either a powder or base form
  - chemicals
  - cocaine, indistinguishable one batch from another that is, until now
  - considered by many to be one of the most addictive of all drugs of abuse
  - dangerous and can cause death
  - doubly dangerous for pregnant women
* is highly addictive, especially in the crack form
* is illegal and addicting
  - lethal because it causes convulsions and cardiac arrhythmias
  - local anaesthetics
  - metabolized by plasma and liver cholinesterases
  - more addictive than the nicotine in tobacco
  - much more potent when injected than when chewing the leaf
  - now an illegal substance
  - often mixed with substances that are poisonous when injected
* is one of the drugs they consume, and it is in competition with amphetamine derivatives
  - most abused drugs in the United States
* is one of the most addictive drugs in common use
  - drugs in society today
  - powerfully addictive street drugs
  - principle drugs being smuggled into the country
  - only addictive if injected
  - plant-derived
  - psychologically addictive and research indicates possible physical addiction
  - readily available in kilo lots in Chile and other Latin American countries
  - risky in any form of use
  - safer taken orally
  - sewn into wigs, inserted under animal skin and hidden in breast implants
  - shorter, used by whites
* is the active ingredient of the coca plant, native only to the Americas
  - currency of the capital
  - drug of illusion par excellance
  - main alkaloid of the coca plant
  - major contributor to economic compulsive violence
  - most prevalent drug in Dallas, with crack the most common form of cocaine being used
  - number one generator of corruption and violence on all levels in the country
  - only drug that transits Israel toward other markets
* is the only local anesthetic that causes vasoconstriction at all doses
  - which also has vasoconstrictive properties
  - pure form of crack
* is the second most abused drug
  - available drug, followed by heroin
  - popular smuggled drug
  - third most common addictive drug, next to alcohol and marijuana
  - unique among abused substances in that acute tolerance develops
  - usually available as cocaine hydrochloride salt, a white powder
  - worth about eight times the value of gold and is sold only for cash
* much more addictive drug than alcohol.
* narcotic drug obtained from the leaves of the coca plant.
* only comes from America, as well as coffee.
* overstimulates the central nervous system and produces an artificial euphoria.
* popular drug among injection drug users.
* potent stimulant that makes an athlete more alert.
* potentiates certain brain chemicals
  - the effects of norepinephrine
* powerful central nervous system stimulant that comes from the South American coca bush
  - reinforcer that has become a popular drug of abuse
* powerful stimulant derived from the Coca plant and comes in a variety of forms
  - drug that comes from the leaves of the South American coca plant
* powerfully addictive drug of abuse
  - that directly affects the brain
  - stimulant that directly affects the brain
* prevents dopamine reuptake by binding to proteins that normally transport dopamine.
* produces a state of excitement or euphoria
  - temporary increase in energy and a sense of euphoria followed by depression
  - both physical and psychological addiction
  - tremendous euphoria, whereas nicotine produces mild euphoria
* provides a powerful, direct hit to the pleasure center of the brain.
* psychomotor stimulant.
* puts the fetus at a higher risk of being stillborn or premature.
* raises fetal blood pressure and heart rate.
* related crime billion dollar a year industry.
* remains the major narcotic brought illegally into the United States.
* short-acting powerful stimulant.
* still poses the most serious drug threat to the United States.
* stimulant and increases the user's heart rate and blood pressure.
* stimulant drug like speed, but much shorter acting
  - obtained from the leaf of the coca plant
* stimulant that can help people's senses
  - is most commonly inhaled as a powder
  - speeds up the work of the body
* stimulant, derived from the leaves of the coca plant
  - medically used as an anesthetic
* stimulates the cells of the central nervous system and cardiovascular system.
* stimulates the central nervous system causing restlessness, tremors, and convulsions
  - system, increasing alertness and activity
* substance that has significant central stimulant action in the central nervous system.
* suppresses appetite and relieves fatigue.
* takes a toll on the body.
* use results in a smaller brain, which results in learning disabilities for the fetus.
* useful pharmaceutical.
  - strong stimulant to the central nervous system, including the brain
  - useful drug for enhancing a special experience
* white crystalline powder that comes from the leaves of the coca plant in South America
  - is crushed finely and snorted
  - powder, often diluted with other ingredients
* white powder that comes from the leaves of the South American coca plant
  - is refined from the coca plant
  - people either snort or dissolve and inject with a needle
* withdraws rapidly from the brain, making the user feel depressed, irritable and fatigued.
* works like an antidepressant.
+ Cocaine, Dangers of using cocaine: Illegal drugs