Deadpool announced that he is getting married. However, he keeps the identity of his bride a mystery, sparking curiosity among his friends and enemies alike, as the new spreads, various Marvel characters, heroes and villains receive invitations to Deadpool's wedding. Many of them are surprised and skeptical, given Deadpool's unpredictable and unconventional nature. Amidst the preparation for the wedding, Deadpool's enemies, including villains like Taskmaster and Typhoid Mary, seize the opportunity to crash the event and try to take down Deadpool. The guests gather at the wedding venue, which happens to be a large spaceship orbiting Earth. Deadpool's friends, including Wolverine and Captain America, show up to support him, although they are wary of the potential chaos that may ensue. As the ceremony begins, the bride's identity is finally revealed, and to everyone's surprise, it is a female version of Deadpool from an alternate reality known as Lady Deadpool.