Hi everyone, so we're back in the hood today to show you guys how to do the reduction of benzopheno. Let's start by introducing our reactants today. So here is our benzopheno. This is a slightly granular white solid. And the most important part of this benzopheno today is its ketone group, which we are going to be reducing with the help of some sodium borohydride over here. So the first step in our reaction is to dissolve our benzopheno into 2 milliliters of methanol. And this can be done just by shaking for a minute. So benzopheno has those two big phenyl rings in its structure. And so it's going to be rather gone polar. Methanol has a moderate polarity, and so it's able to dissolve a wide range of substances. And that's one of the reasons that we're using it today. The other reason that we're using methanol is because it's an aprodic solvent. So when I introduce this sodium borohydride into the system, it's going to provide hydrogen anions or hydrides. And those hydrides are going to be highly reactive with protons, like the ones that are freely available in water. So if I dumped this sodium borohydride into a product solvent, like water, this wouldn't actually react with anything that I wanted to, it just reacts with the water. But if I do it in an aprodic solvent like this, it will not react with the methanol, and it will react with the benzopheno that I wanted to. I'm going to fold this into a cute little taco. And I'm going to add the sodium borohydride about a half at a time. And what we'll see when the sodium borohydride gets in there is we see some bubbles forming in solution. Now methanol is an aprodic solvent, like I said. But it's unavoidable. There's always going to be a little bit of trace water around or something with a proton. That those hydrides can react with. And so the hydrides are finding some random protons throughout the system, and they're reacting with them to form hydrogen gas. That hydrogen gas, if you produce too much of it at a time, can actually be dangerous because it's highly flammable. We've got the scale that we're working on in this lab. And in the complete absence of a heat source, I'm not worried about the flammability too much, but always something to be aware of when using sodium borohydride. I've got a little bit plastered on the side of the test tube here, so I'm just going to crawl some liquid along the side and try to collect that. There we go. And so this reaction is going to continue to react and bubble for probably about the next five minutes or so. But the reaction is going to continue to proceed for about 20 minutes. At which time I would expect this bubbling to have died down completely. And the benzophenone should have all been reduced to its alcohol product. So at that time, we're going to come back and show you guys the work up for how we collect that product. Okay, so here's our reduced benzophenone reaction after that 20 minute wait time. I've also had it sitting in a little ice water bath for five or 10 minutes here. Just get nice and cold. And what I hope to see is upon the addition half mill of water, half mill of ice water here, I would hope to see that alcohol product precipitate. And I want that solution to get nice and cloudy. So I see a couple little solids floating around. Let's put that back on ice for a moment and come back once we see solids. One thing when you are collecting by vacuum filtration, make sure you can see the solids in your solution before transferring it to your filter apparatus. If it's all liquid, it's going to get sucked right through and you're going to lose your product completely. Okay, so we are back after our 20 minute wait period in order to quench the reaction or to use up any of the remaining sodium borrower hydride. I've added a mill later ice water here. And you can see that our alcohol product has formed and it's that white, tasty solid, which is clouding up our solution here. So as for the instructions, just to make sure that we are getting the full precipitation of our products, I'm going to add another half mill of ice water. And get that nice and cold. And now that we have our solid, we can collect our product by vacuum filtration using this cute little version of it. So we are going to turn on that noisy vacuum. Perfect. And to adhere that filter paper to the first funnel, I'm going to use a little bit of cold water, just a few drops. And for our mixture in, and it is not pouring super well for me, I'm going to need to scrape that with a spatula. So I've gotten most of it out. I'm going to go ahead and rinse out all of the stuff stuck to the side to my test tube by just adding a little bit of ice water. Okay, test tube as much cleaner now. So I've gotten most of my products out. And you can see that the liquid is being pulled through and is dripping down into the collection glass here. And we're being left with a fairly white, shiny, crystallized product up top. And that is our alcohol product called 11 Diapidal Methanol. So the air is being sucked through the filter paper, which is down here at the bottom of this cold in this first funnel. So I want the air to be passing over the product and I'll just dry it. So I'm going to get it down off the sides and get it down against that filter paper. Now the good news is that the Diapidal Methanol product, that's fairly non-polar. So it's weakly attracted to water and that makes it dry faster. And the bad news is that water has a very low vapor pressure. So it's going to take longer than other solvents to dry. So with those two effects in combination, this is going to take about 10 or 15 minutes and it's off now. So after 10 or 15 more minutes of drying, I'm going to go ahead and collect this product for you guys. I'm going to get a mass of melting points and IR for you to analyze. And with that, you guys should be able to prove that the reaction was successful. So thank you for watching and good luck with your work.