The project aims at realising smart medical implants that interact with the surrounding bone tissue. Poor restructures of shape memory alloys have been created and tested in vitro. It is a goal to identify optimized implants structures in order to specifically enhance osteoporotonic cell function and reach a superior implant performance in bone tissue. Solid and complex shaped porous nickel titanium lattice structures were developed by selective lacer melting and were physically chemically characterized. As built, nickel titanium parts show pseudo-elastic behaviour at room or body temperature. Strings of up to 5% have been shown in solid parts and up to 7% in open pour of scuffolds. The physical properties, including the phase transition temperatures, can be tailored not only by the composition of the starting powder, but also by the processing parameters of selective lacer melting and per subsequent thermal treatment. This allows for the fabrication of pseudo-elastic and pseudo-plastic nickel titanium structures from the same starting material with locally predefined anisotropic properties. The damping properties of nickel titanium are also associated with a martenside austenite phase transformation. The results indicate that selective lacer melting of nickel titanium is suitable for the fabrication of medical implants with ultra-hyme mechanical damping capacity. For the investigation of mechanical cell stimulation in a three-dimensional structure, a compression perfusion bioreactor has been developed. The bioreactor system serves as an in-utro model for an orthotopic implantation site, which allows for the testing of the nickel titanium scuffolds under physiological conditions. The novelty of this technology lies in the fact that smart implantable structures can be produced with predefined physical and mechanical properties. Due to the combination of the mechanical stability of nickel titanium constructs, the variability of the three-dimensional geometry and the biocompatibility, there is a reasonably high potential to use these systems as implant materials in the dental or spinal field.