Cicocel disease or cicocel anemia is an autosomal recessive disorder and affects mostly descendants from tropical Africa and to a lesser degree also patients who have Mediterranean or Middle Eastern roots. And this autosomal recessive disorder when two patients or a man and a woman with that cicocel trait come together, their chances of having an offspring with actual cicocel disease is 25%. Where 55% might be only carriers and another 25% of their offspring might be unaffected. Which is why it is so important for us to educate our patients who have cicocel trait and send them refer them to genetic counseling so that they make the best decision for them regarding starting a family.