2-三氟甲基吡咯

2-三氟甲基吡咯是一种有机化合物，化学式为。它可由吡咯和三氟碘甲烷在硫酸亚铁和硫酸存在下于二甲基亚砜中反应制得。Hys, Vasyl Yu; et al. Functionalization of 2-Trifluoromethyl-1H-pyrrole: A Convenient Entry into Advanced Fluorinated Building Blocks Including all Isomeric 2-(Trifluoromethyl)prolines. European Journal of Organic Chemistry, 2020 (25). 3896-3905. .Kino, Totsuhito; et al. Trifluoromethylation of various aromatic compounds by CF3I in the presence of Fe(II) compound, H2O2 and dimethylsulfoxide. Journal of Fluorine Chemistry, 2010. 131 (1): 98-105. 它和二碳酸二叔丁酯在DMAP存在下于二氯甲烷中反应，可以得到N-叔丁氧羰基-2-三氟甲基吡咯。它的19F NMR可使用1-氟-3-硝基苯为内标进行检测。Du, Ya; et al. Strongly Reducing, Visible-Light Organic Photoredox Catalysts as Sustainable Alternatives to Precious Metals. Chemistry - A European Journal, 2017. 23 (46): 10962-10968. .

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Category:三氟甲基化合物
Category:吡咯