4-五氟乙基苯甲醛

4-五氟乙基苯甲醛是一种有机氟化合物，化学式为C9H5F5O。它可由4-碘苯甲醛和五氟乙基亚铜在二甲基甲酰胺中反应制得。Jordi Mestre; et al. “Ligandless” Pentafluoroethylation of Unactivated (Hetero)aryl and Alkenyl Halides Enabled by the Controlled Self-Condensation of TMSCF3-Derived CuCF3. J. Org. Chem. 2019, 84, 23, 15087–15097. .它和甲胺反应，可以得到相应的亚胺，经硼氢化钠还原后，可以得到N-甲基-4-五氟乙基苄胺。Mehul H. Jesani; et al. Selective Defluorination of Trifluoromethyl Substituents by Conformationally Induced Remote Substitution. Angewandte Chemie, International Edition (2024), 63(24), e202403477. .

参考文献

Category:五氟乙基化合物
Category:苯甲醛