1-萘亚甲基丙二腈

1-萘亚甲基丙二腈是一种有机化合物，化学式为C14H8N2。它可由1-萘甲醛和丙二腈加热反应得到。Weifan Wang; et al. Catalyst-free and Solvent-free Cyanosilylation and Knoevenagel Condensation of Aldehydes. ACS Sustainable Chem. Eng. 2019, 7, 1, 1718–1722. .

反应

1-萘亚甲基丙二腈可以被硼氢化钠在甲醇中还原为1-萘亚甲基丙二腈。Dapeng Zhang; et al. Preparation of O-Protected Cyanohydrins by Aerobic Oxidation of α-Substituted Malononitriles in the Presence of Diarylphosphine Oxides. Org. Lett. 2019, 21, 8, 2597–2601. .它和三氟甲基三甲基硅烷在乙酸钠存在下于二甲基甲酰胺中反应，可以得到[2,2,2-三氟-1-(1-萘基)乙基]丙二腈。Dilman, Alexander D.; et al. Nucleophilic trifluoromethylation of arylidenemalononitriles. Tetrahedron Letters (2008), 49 (28), 4352-4354. .

参考文献

Category:丙二腈