5-氯吡嗪-2-甲酸甲酯

5-氯吡嗪-2-甲酸甲酯是一种有机氯化合物，化学式为C6H5ClN2O2。它可由5-氯吡嗪-2-甲酸和氯化氢的甲醇溶液中回流制得。Sato, Nobuhiro; et al. Studies on pyrazines. 7. The synthesis of 5-chloropyrazinecarboxylic acid. Journal of Heterocyclic Chemistry (1982), 19 (2), 407-408. .它和三甲基溴硅烷在乙腈中反应，可以得到5-溴吡嗪-2-甲酸甲酯。Kim, Dae-Shik; et al. Synthesis of BACE1 Inhibitors E2609/E2071 via Oxime-Olefin Cycloaddition Following Process Risk Mitigation Strategy. Organic Process Research & Development (2022), 26 (3), 804-816. .
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Category:吡嗪
Category:甲酯