异麦角酸二乙酰胺

异麦角酸二乙酰胺（iso-LSD或(5R-8S)-LSD，化学式：C20H25N3O）是一种，可作为5-羟色胺受体调节剂。麦角酸二乙酰胺（LSD）在碱存在下会异构化为iso-LSD，因此它是LSD合成过程中的常见污染物。Shulgin AT (1980). "Hallucinogens". In Burger A, Wolf ME (eds.). Burger's Medicinal Chemistry. Vol. 3 (4 ed.). New York: Wiley. pp. 1109–1137. ISBN 978-0-471-01572-7. OCLC 219960627. The lysergic acid four-ring nucleus possesses two asymmetric centers requiring four isomeric forms. All have been prepared and the hallucinogenic action is uniquely ascribable to the stereoisomer 60.33a. The 8-substituent, lying between two unsaturated systems, is easily epimerized with base. Thus a common synthetic contaminant in syntheses involving the lysergic acid ring system is the pharmacologically inert iso form as shown in 60.33b.
参考文献

外部链接
 d-iso-LSD - Isomer Design

Category:二乙氨基化合物
Category:对映纯药物
Category:麦角酰胺