WNT974

WNT974是一种有机化合物，化学式为C23H20N6O。它可以和为原料，经多步反应制得。Dai Cheng; Jun Liu; Dong Han; et al. Discovery of Pyridinyl Acetamide Derivatives as Potent, Selective, and Orally Bioavailable Porcupine Inhibitors. ACS Med. Chem. Lett. 2016, 7, 7, 676–680. .它是一种Wnt信号抑制剂。Shuying Xie; Wenbin Fu; Guangju Yu; et al. Discovering small molecules as Wnt inhibitors that promote heart regeneration and injury repair. Journal of Molecular Cell Biology, 2020. 12 (1): 42-54. .Jun Liu; Shifeng Pan; Mindy H. Hsieh; et al. Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974. Proceedings of the National Academy of Sciences of the United States of America (2013), 110(50). .
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Category:吡嗪
Category:酰胺
Category:联吡啶
Category:2010年代发现的物质