1-(9-芴甲氧羰基)-4-羧甲基哌嗪

1-(9-芴甲氧羰基)-4-羧甲基哌嗪是一种有机化合物，化学式为C21H22N2O4。它可以4-叔丁氧羰基哌嗪-1-乙酸叔丁酯和N-(9-芴甲氧羰基氧基)丁二酰亚胺为原料反应制得。Zeneca Ltd.; Dutta, Anand Swaroop. Preparation of cyclic peptides as cell adhesion inhibiting compounds. 1997. WO9749731 A1.它和4-(3,5-二甲氧基苯甲酰氨基)丁酸在二异丙基乙胺存在下反应，可以得到4-[4-(3,5-二甲氧基苯甲酰氨基)-1-氧代丁基]-1-羧甲基哌嗪。Revotar Biopharmaceuticals AG. Novel multi-cyclic compounds comprising dihydroxy- or dimethoxyphenyl subunits and their use as selectin antagonists. 2007. EP1764094 A1.

参考文献

拓展阅读
 Yuqing Jia; et al. Development of Inhibitors, Probes, and PROTAC Provides a Complete Toolbox to Study PARK7 in the Living Cell. J. Med. Chem. 2024, 67, 10, 7935–7953. 

Category:哌嗪
Category:9-芴甲氧羰基化合物