3-丁炔酸

3-丁炔酸是一种有机化合物，化学式为C4H4O2。它可由炔丙基溴和镁在氯化汞催化下在乙醚中反应，再向溶液中通入二氧化碳、酸处理后得到。Fedor Romanov-Michailidis, Laure Guénée, Alexandre Alexakis. Enantioselective Organocatalytic Fluorination-Induced Wagner–Meerwein Rearrangement. Angew Chem Int Ed, 2013. 52 (35): 9266-9270. .它也能通过3-丁炔醇经硝酸-重铬酸钠-高碘酸钠氧化制得。Ata Abbas, Bengang Xing, Teck-Peng Loh. Allenamides as Orthogonal Handles for Selective Modification of Cysteine in Peptides and Proteins. Angew Chem Int Ed, 2014. 53 (29). .它和18%碳酸钾溶液于40 °C反应，再酸化后，可以异构为丁二烯酸。G. Eglinton,   E. R. H. Jones,   G. H. Mansfield  and  M. C. Whiting. Researches on acetylenic compounds. Part XLV. The alkaline isomerisation of but-3-ynoic acid. J. Chem. Soc., 1954, 3197-3200. .
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Category:炔酸