2-溴-5-硝基咪唑

2-溴-5-硝基咪唑是一种有机溴化合物，化学式为C3H2BrN3O2。它可由2,5-二溴-4-硝基咪唑在冰乙酸中和碘化钾、亚硫酸钠反应制得。A concise and sequential synthesis of the nitroimidazooxazole based drug, Delamanid and related compounds. RSC Adv., 2020,10, 17085-17093. .它和4-溴-1-丁烯在碳酸钾存在下反应，可以得到2-溴-1-(3-丁烯-1-基)-4-硝基咪唑。7-Substituted 2-Nitro-5,6-dihydroimidazo[2,1-b][1,3]oxazines: Novel Antitubercular Agents Lead to a New Preclinical Candidate for Visceral Leishmaniasis. J. Med. Chem. 2017, 60, 10, 4212–4233. .

参考文献

Category:溴咪唑
Category:硝基咪唑