3-丁炔-2-醇

3-丁炔-2-醇是一种具有手性的有机化合物，化学式为C4H6O，它存在R型和S型两种异构体。

反应
3-丁炔-2-醇和甲磺酰氯在三乙胺存在下于二氯甲烷中反应，可以得到3-丁炔-2-醇甲磺酸酯。Fananas, Francisco J.; Mendoza, Abraham; Arto, Tamara; Temelli, Baris; Rodriguez, Felix. Scalable Total Synthesis of (-)-Berkelic Acid Using a Protecting-Group-Free Strategy. Angew Chem Int Ed, 2012. 51 (20). .它和4-氟碘苯在催化下反应，可以得到4-(4-氟苯基)-3-丁炔-2-醇。Pieczykolan, Michal; Narczyk, Aleksandra; Stecko, Sebastian. The Synthesis of Chiral β,β-Diaryl Allylic Alcohols and Their Use in the Preparation of α-Tertiary Allylamines and Quaternary α-Amino Acids. J. Org. Chem. 2017, 82, 11, 5636–5651. .
参考文献

Category:炔醇