三氟乙醛肟

三氟乙醛肟是一种有机化合物，化学式为C2H2F3NO。它可由2,2,2-三氟-1,1-乙二醇和羟胺反应制得。Ondřej Hylse, et al. A Concise Synthesis of Forskolin. Angew Chem Int Ed. 2017. 56 (41): 12586-12589. .它和N-溴代丁二酰亚胺反应，可以得到2,2,2-三氟-1-溴乙醛肟。Bagal, Sharanjeet Kaur; Gibson, Karl Richard; Kemp, Mark Ian; Poinsard, Cedric; Stammen, Blanda Luzia; Denton, Stephen Martin; Glossop, Melanie Susanne. Pyridine derivatives as voltage-gated sodium channel modulators and their preparation, pharmaceutical compositions and use in the treatment of pain. 2008. WO2008135826 A2.它和苯乙炔、二乙酸碘苯反应，可以得到5-苯基-3-三氟甲基异𫫇唑。Raoni S. B. Gonçalves, et al. A one-pot synthesis of 3-trifluoromethyl-2-isoxazolines from trifluoromethyl aldoxime. Beilstein Journal of Organic Chemistry, 2013. .
参考文献

Category:肟
Category:三氟甲基化合物