2-氯-5-硝基吡啶

2-氯-5-硝基吡啶是一种有机氯化合物，化学式为C5H3ClN2O2。它可由6-甲氧基-3-硝基吡啶和三氯氧磷在二甲基甲酰胺中反应制得；Lai, Long-Li; Lin, Pen-Yuan; Wang, Jy-Shih; Hwu, Jih Ru; Shiao, Min-Jen; Tsay, Shwu-Chen. Substituent effect on the chlorination of 2-alkoxypyridines to give 2-chloropyridines under Vilsmeier-Haack conditions. Journal of Chemical Research, Synopses (1996), (4), 194-195.或由2-氨基-5-硝基吡啶重氮化后和氯化亚铜反应得到。Deaminative chlorination of aminoheterocycles. Nature Chemistry (2022), 14(1), 78-84. .它和苯硼酸在四(三苯基膦)钯催化下反应，可以得到5-硝基-2-苯基吡啶。Olivier Lohse. The Palladium Catalysed Suzuki Coupling of 2- and 4-Chloropyridines. Synlett 1999; 1999(1): 45-48 .

参考文献

Category:氯吡啶
Category:硝基吡啶