3-甲基苯甲醚

3-甲基苯甲醚是一种有机化合物，化学式为C8H10O。它可由3-甲基苯酚和碳酸二甲酯在十羰基二锰催化反应制得。Khusnutdinov, R. I., Shchadneva, N. A., & Mayakova, Y. Y. (2015). Methylation of phenol and its derivatives with dimethyl carbonate in the presence of Mn2(CO)10, W(CO)6, and Co2(CO)8. Russian Journal of Organic Chemistry, 51(3), 330–334. 它和NBS在乙腈中于室温反应，可以得到4-溴-3-甲基苯甲醚；而在四氯化碳中光照回流，得到的主产物为3-甲氧基溴化苄。M. Carmen Carreno, Jose L. Garcia Ruano, Gema Sanz, Miguel A. Toledo, and Antonio Urbano. J. Org. Chem. 1995, 60, 16, 5328–5331 碘-氧化汞在二氯甲烷中Orito, K., Hatakeyama, T., Takeo, M., & Suginome, H. (1995). Iodination of Alkyl Aryl Ethers by Mercury(II) Oxide-Iodine Reagent in Dichloromethane. Synthesis, 1995(10), 1273–1277. ，或NIS-TFA在乙腈中对其碘化，可以得到4-碘-3-甲基苯甲醚。Two Stereoinduction Events in One C−H Activation Step: A Route towards Terphenyl Ligands with Two Atropisomeric Axes. Angew. Chem. Int. Ed. 2018. . Supp Info. pp 19.

参考文献

Category:间甲苯基化合物
Category:3-甲氧基苯基化合物