List of banned substances in baseball

Major League Baseball's drug policy prohibits players from using, having, selling, allowing the sale of, distributing, or allowing the distribution of any Drug of Abuse and/or Steroid. Any and all drugs or substances listed under Schedule II of the Controlled Substances Act are considered drugs of abuse covered by the Program. Players who require prescription medication can still use it with a "Therapeutic Use Exemption" granted by MLB.

In December 2019, MLB removed cannabinoids and added cocaine and opiates to its list of Drugs of Abuse. However, players were told that they could still be suspended for possessing or selling cannabis, or driving under the influence of cannabis.

List of banned substances (not exhaustive)

Drugs of abuse
 Synthetic cannabinoids
 Cocaine
 LSD
 Opiates (e.g., fentanyl, oxycodone, heroin, codeine, and morphine)
 Amphetamines (e.g., MDMA (Ecstasy), MDA, Meth)
 "Bath salts" (e.g., cathinone, synthetic cathinone, MDPV)
 GHB
 Phencyclidine (PCP)

Performance enhancing substances (steroids, growth factors, hormone modulators, masking agents)

 Androstanediol
 Androstanedione
 Androstatrienedione (ATD)
 Androstanolone
 Androstenediol
 Androstenedione
 Androst-2-en-17-one (2-androstenone, delta-2)
 Androsterone
 Bolandiol
 Bolasterone
 Boldenone
 Boldione
 Calusterone
 Clenbuterol
 Clostebol (chlortestosterone)
 Danazol
 Dehydrochloromethyltestosterone (DHCMT, turinabol)
 Dehydroepiandrosterone (DHEA)
 Desoxy-methyltestosterone (DMT, madol)
 Dihydrotestosterone
 Drostanolone
 Epiandrosterone
 Epi-dihydrotestosterone
 Epitestosterone
 Ethylestrenol
 Fluoxymesterone
 Formebolone
 Furazabol
 Gestrinone
 Halodrol
 4-Hydroxytestosterone 
 7-Keto-DHEA
 Mestanolone
 Mesterolone
 Methandienone
 Methandriol
 Methasterone (superdrol)
 Methenolone
 Methylclostebol
 Methyldienolone
 Methylnortestosterone
 Methylstenbolone (ultradrol, m-sten)
 Methyltestosterone
 Methyltrienolone (metribolone)
 Mibolerone
 Nandrolone
 Norbolethone
 Norandrostenediol
 Norandrostenedione
 Norandrosterone
 Norbolethone (genabol)
 Norclostebol
 Norethandrolone
 Noretiocholanolone
 Oxabolone
 Oxandrolone
 Oxymesterone
 Oxymetholone
 Prasterone (DHEA)
 Promagnon
 Prostanozol
 Quinbolone
 Selective androgen receptor modulators (SARMs)
 Stanozolol
 Stenbolone
 Testosterone
 Tetrahydrogestrinone
 Tibolone
 Trenbolone
 Zeranol
 Zilpaterol
 Any salt, ester, or ether of a drug or substance listed above
 Human growth hormone (hGH), including all fragments (e.g., AOD9604, hGH fragment 176-191) and releasing factors including GHRHs (e.g., CJC-1295, sermorelin, tesamorelin), GHSs (e.g., ghrelin and its mimetics (e.g., anamorelin, ibutamoren (MK-0677), ipamorelin), and peptides (e.g., alexamorelin, GHRP-2 (pralmorelin), GHRP-6, hexarelin)
 Insulin-like growth factor (IGF-1), including all isomers of IGF-1 (mechano growth factors, thymosin beta-4)
 Gonadotrophins (hCG), including LH and hCG
 Corticotrophins, including releasing factors (corticorelin)
 Erythropoiesis stimulating agents, including (erythropoietin (EPO), darbepoetin (dEPO), hematide, methoxy polyethylene glycol-epoetin beta (CERA))
 Aromatase inhibitors, including anastrozole, androstatrienedione (ATD), androstenetrione (6-OXO), aminoglutethimide, arimistane, exemestane, formestane, letrozole, and testolactone
 Selective estrogen receptor modulators (SERMs), including bazedoxifene, ospemifene, raloxifen, tamoxifen, and toremifen
 Other Anti-estrogens, including clomiphene, cyclofenil, and fulvestrant
 Myostatin modifying agents, including myostatin inhibitors (e.g., follistatin)
 Metabolic modifying agents, including Peroxisome Proliferator Activated Receptor δ (PPARδ) agonists (GW1516, GW501516, GW0742), AMP-activated protein kinase (AMPK) activators (AICAR, SR9009 (stenabolic)), meldonium (mildronate), trimetazidine
 HIF stabilizers, including roxadustat (FG-4592), molidustat (BAY 85-3934), FG-2216, BAY 87-2243.
 Masking agents, including diuretics, desmopressin, probenecid, plasma expanders (e.g., intravenous administration of albumin, dextran, hydroxyethyl starch and mannitol)
 Diuretics include acetazolamide, amiloride, bumetanide, canrenone, chlorthalidone, etacrynic acid, furosemide, indapamide, metolazone, spironolactone, thiazides (e.g., bendroflumethiazide, chlorothiazide, hydrochlorothiazide), triamterene, vaptans 
 Gene doping, the use of nucleic acids that may alter genome sequences and/or gene expression, including gene editing, gene silencing, gene transfer, genetically modified cells

Stimulants

 Adrafinil
 Amfepramone (diethylproprion)
 Amiphenazole
 Amphetamine
 Amphetaminil
 Armodafinil
 Benfluorex
 Benzphetamine
 Benzylpiperazine
 Bromantan
 Carphedon
 Cathine (norpseudoephedrine)
 Chloroamphetamine
 Clobenzorex
 Cropropamide
 Crotetamide

 Dimethylamylamine
 Dimethylamphetamine
 1,3-Dimethylbutylamine (DMBA)
 Ephedrine
 Etamivan
 Ethylamphetamine
 Etilefrine
 Famprofazone
 Fenbutrazate
 Fencamfamine
 Fenethylline
 Fenfluramine
 Fenproporex
 Furfenorex
 Heptaminol
 Isometheptene
 Levmetamphetamine
 Lisdexamphetamine
 Meclofenoxate
 Mefenorex
 Mephentermine
 Mesocarb
 Methylephedrine
 Methylhexaneamine (dimethylamylamine, DMAA)
 Methylphenidate
 Modafinil
 N,alpha-Diethylphenylethylamine (N,a-DEPEA)
 N-ethyl-1-phenyl-2-butanamine
 Nikethamide
 Norfenefrine
 Norfenfluramine
 Octodrine (DMHA)
 Octopamine
 Oxilofrine
 Parahydroxyamphetamine
 Pemoline
 Pentetrazol
 Phendimetrazine
 Phenethylamine
 Phenmetrazine
 Phenpromethamine
 Phentermine
 Prenylamine
 Prolintane
 Propylhexedrine
 Pyrovalerone
 Selegiline
 Sibutramine
 Strychnine
 Tuaminoheptane

Prohibited Substances may be added to the list with a unanimous vote of HPAC, provided that the addition by the federal government of a substance to Schedule I, II, or III will automatically result in that substance being added to the list.

References

Category:Baseball lists
Category:Drugs