2021 Buffalo Bills season

The 2021 season was the Buffalo Bills' 52nd in the National Football League, and their fifth under the head coach Sean McDermott.

Draft

 2021 Buffalo Bills Draft Round  Selection  Player  Position  College  Notes 1  30 Gregory Rousseau  DE  Miami (FL) Opted out of the 2020 CFB season while at the University of Miami  2  61 Carlos Basham Jr.  DE  Wake Forest  3  93 Spencer Brown  OT Northern Iowa   5  161 Tommy Doyle  OT  Miami (OH)  from Las Vegas 6  203 Marquez Stevenson  WR  Houston  from Washington via Las Vegas and Miami and Houston 212 Damar Hamlin  S  Pittsburgh  from New Orleans via Houston 213 Rachad Wildgoose  CB  Wisconsin  7  236 Jack Anderson  OG  Texas Tech  from Carolina

Regular season
Schedule
The Bills 2021 schedule was announced on May 12.

 Week Date Opponent Result Record Venue Recap 1 September 12 Pittsburgh Steelers L 16–23 0–1 Highmark Stadium Recap 2 September 19 at Miami Dolphins W  35–0 1–1 Hard Rock Stadium Recap 3 September 26 Washington Football Team W 43–21 2–1 Highmark Stadium Recap 4 October 3 Houston Texans W 40–0 3–1 Highmark Stadium Recap 5 October 10 at Kansas City Chiefs W 38–20 4–1 Arrowhead Stadium Recap 6  at Tennessee Titans L 31–34 4–2 Nissan Stadium Recap 7 Bye 8 October 31 Miami Dolphins W 26–11 5–2 Highmark Stadium Recap 9 November 7 at Jacksonville Jaguars L 6–9 5–3 TIAA Bank Field Recap 10 November 14 at New York Jets W 45–17 6–3 MetLife Stadium Recap 11 November 21 Indianapolis Colts L 15–41 6–4 Highmark Stadium  Recap 12 November 25 at New Orleans Saints W 31–6 7–4 Caesars Superdome Recap 13  New England Patriots L 10–14 7–5 Highmark Stadium Recap 14 December 12 at Tampa Bay Buccaneers L 27–33  7–6 Raymond James Stadium Recap 15 December 19 Carolina Panthers W  31–14 8–6 Highmark Stadium Recap 16 December 26 at New England Patriots W 33–21 9–6 Gillette Stadium Recap 17 January 2 Atlanta Falcons W 29–15 10–6 Highmark Stadium Recap 18 January 9 New York Jets W 27–10 11–6 Highmark Stadium Recap
Note: Intra-division opponents are in bold text.

Standings

Division

Conference

Postseason

Schedule
 Round Date Opponent (seed) Result Record Venue Recap Wild Card  New England Patriots (6) W 47–17 1–0 Highmark Stadium Recap Divisional January 23 at Kansas City Chiefs (2) L 36–42  1–1 Arrowhead Stadium Recap

Category:2021 National Football League season by team
Category:Buffalo Bills seasons