E. B. Ford

Edmund Brisco Ford FRS (23 April 1901 – 2 January 1988) was a British ecological geneticist. He was a leader among those British biologists who investigated the role of natural selection in nature. As a schoolboy Ford became interested in lepidoptera, the group of insects which includes butterflies and moths. He went on to study the genetics of natural populations, and invented the field of ecological genetics. Ford was awarded the Royal Society's Darwin Medal in 1954. Later, in 1968, he was awarded UNESCO's Kalinga Prize for the popularisation of science.

 Career 
Specialising in genetics, he was appointed Oxford University Reader in Genetics in 1939 and was the Director of the Genetics Laboratory, 1952–1969, and Professor of Ecological Genetics 1963–1969. Ford was one of the first scientists to be elected a Fellow of All Souls College since the seventeenth century.

Ford had a long working relationship with R.A. Fisher. By the time Ford had developed his formal definition of genetic polymorphism,Ford E.B. 1940. Polymorphism and taxonomy. In Huxley J. The new systematics. Oxford. Fisher had got accustomed to high selection values in nature. He was most impressed by the fact that polymorphism concealed powerful selective forces (Ford gave human blood types as an example). Like Fisher, he continued the natural selection versus genetic drift debate with Sewall Wright, whom Ford believed put too much emphasis on genetic drift. It was as a result of Ford's work, as well as his own, that Dobzhansky changed the emphasis in the third edition of his famous text from drift to selection.Dobzhansky T. 1951. Genetics and the origin of species. 3rd ed, Columbia University Press N.Y.


Ford predicted that human blood group polymorphisms might be maintained in the population by providing some protection against disease.Ford E.B. 1942. Genetics for medical students. Methuen, London. Six years after this prediction it was found to be so,Ford E.B. 1949. Polymorphism. Biological Reviews 20, 73. and furthermore, heterozygous advantage was decisively established by a study of AB x AB crosses.Chung C.S. and Morton N.E. 1961 Selection at the ABO locus. Am J Human Genetics 13, 9–27. His magnum opus was Ecological genetics, which ran to four editions and was widely influential.Ford E.B. 1975. Ecological genetics, 4th ed. Chapman and Hall, London. He laid much of the groundwork for subsequent studies in this field, and was invited as a consultant to help set up similar research groups in several other countries.

Amongst Ford's many publications, perhaps the most popularly successful was the first book in the New Naturalist series, Butterflies.Ford E.B. 1945, 3rd ed 1977. Butterflies. New Naturalist #1 Collins, London. Ford also went on in 1955 to write Moths Ford E.B. 1955, 3rd edn 1972. Moths. New Naturalist #30 HarperCollins, London. in the same series, one of only a few to have authored more than one book in the series.

 Ecological genetics 
E.B. Ford worked for many years on genetic polymorphism.  Polymorphism in natural populations is frequent; the key feature is the occurrence together of two or more discontinuous forms of a species in some kind of balance. So long as the proportions of each form is above mutation rate, then selection must be the cause. As early as 1930 Fisher had discussed a situation where, with alleles at a single locus, the heterozygote is more viable than either homozygote. That is a typical genetic mechanism for causing this type of polymorphism. The work involves a synthesis of field research, taxonomy, and laboratory genetics.Huxley J.S. 1955. Morphism and evolution. Heredity 9, 1–52.

 References 

Category:1901 births
Category:1988 deaths
Category:English evolutionary biologists
Category:English geneticists
Category:Ecologists
Category:English science writers
Category:Academics of the University of Oxford