Myelodysplastic syndrome

The Myelodysplastic syndrome (MDS) is a group of diseases that affect the production of blood. These diseases were formerly known as preleukemia, mostly because they can lead to leukemia.


Overview

Myelodysplastic syndromes affect the bone marrow stem cells. The production of blood does not rely on good stem cells, but ones that have been modified genetically. This means that the production of red blood cells, sometimes of white blood cells and blood platelets changed. The production becomes inefficient, or goes wrong altogether. Most of the time, this manifests in anemia. Depending on the severity of the condition, it can also cause hemorrhages, and infections with fever.

Epidemiology

Most of those who have these conditions are 60 years or older, but the younger can get it too, especially if they went through a form of chemotherapy. Most of the sufferers die from the disease, usually after six to thirty months. The only known cure is a stem cell transplant. About a third of those suffering contract leukemia within a few months to years. 

Category:Blood disorders