1550

Events 
 January 6 – Spanish Captain Hernando de Santana founds the city of Valledupar in what is now Colombian territory.
 February 7 – Julius III becomes Pope.
 The first book in Slovenian, Abecedarium, written by Protestant reformer Primoz Trubar, is printed in Tübingen, Germany.
 Nostradamus' first almanac is written.
 Helsinki, the capital of Finland, is founded by Gustav Vasa.