1751

Events 
 Adam Smith is appointed professor of logic at the University of Glasgow
 March 25 – For the last time, New Year's Day is legally on March 25 in England and Wales.
 March 31 – The future King George III of the United Kingdom succeeds his father as Prince of Wales.  His mother Augusta of Saxe-Gotha becomes Dowager Princess of Wales.
 First publication of Encyclopédie
 The Academy and College of Philadelphia, the predecessor to the private University of Pennsylvania, is founded.
 Pennsylvania Hospital, the first hospital in the British colonies, is founded.

 Births 
 March 16 – James Madison, American politician, fourth President of the United States (d. 1836)

 Deaths 
 March 31 – Frederick, Prince of Wales, member of the British Royal Family (b. 1707)