1450s

The 1450s was the decade that started on January 1, 1450 and ended on December 31, 1459. It is distinct from the decade known as the 146th decade which began on January 1, 1451 and ended on December 31, 1460.
 Events 

Fall of Constantinople (now called Istanbul).
France wins the Hundred Years' War against England.
The first printing press is made in Europe by Johann Gutenberg.
The Gutenberg Bible is the first book printed with movable type.
Siege of Belgrade.
War of the Roses starts.

 Births 
Queen Isabella of Castile 
Christopher Columbus, Italian sailor
Leonardo da Vinci, Italian inventor
Girolamo Savonarola, Italian religious reformer 
Ferdinand II of Aragon

 Deaths 
Murad II, Ottoman Sultan 
John Kemp, Archbishop of Canterbury