1516

Events
 The Royal Mail is established

 Births 
 January 16 – King Bayinnong, king of the Toungoo dynasty of Burma
 February 18 – Mary I of England

 Deaths 
 January 23 – King Ferdinand II of Aragon
 August 9 – Hieronymus Bosch, Dutch painter
 November 26 – Giovanni Bellini, Italian Renaissance painter