Ibuprofen

Ibuprofen ni imiti yo mu cyiciro cya nonsteroidal anti-inflammatory (NSAID) ikoreshwa mu kuvura ububabare, umuriro, n’ububabare. Ibi birimo imihango ibabaza, migraine, na rubagimpande ya rubagimpande. Irashobora kandi gukoreshwa mugufunga patent ductus arteriosus kumwana utagejeje igihe. Ishobora gukoreshwa  biciye mukanwa cyangwa  mumitsi. Mubisanzwe itangira gukora mugihe kingana n isha imwe.

Ingaruka zisanzwe zirimo gutwika no guhubuka. Ugereranije nizindi NSAIDs, irashobora kugira ingaruka nke nko kuva amaraso gastrointestinal. Yongera ibyago byo kunanirwa k'umutima, kunanirwa kw'impyiko, no kunanirwa kw'umwijima. Mugihe gito, ntabwo bigaragara ko byongera ibyago byo kurwara umutima ; icyakora, kuri dosiye ndende irashobora. Ibuprofen irashobora kandi kwangiza asima. Nubwo bidasobanutse niba ari umutekano mugihe cyo gutwita hakiri kare, bigaragara ko ari bibi mugihe cyo gutwita nyuma bityo ntibisabwa. Koresha mugihe konsa ari umutekano. Kimwe nizindi NSAIDs, ikora ibuza umusaruro wa prostaglandine kugabanya ibikorwa bya enzyme cyclooxygenase. Ibuprofen nintege nke zo kurwanya inflammatory kurusha izindi NSAIDs.

Ibuprofen yavumbuwe mu 1961 na Stewart Adams muri Boots UK Limited hanyuma ibanza kugurishwa nka Brufen. Iraboneka munsi yizina ryubucuruzi, harimo Nurofen, Inama na Motrin. Yashyizwe ku isoko bwa mbere mu 1969 mu Bwongereza no muri Amerika mu 1974. Ari kurutonde rwumuryango wubuzima ku isi urutonde rwimiti yingenzi. Iraboneka nkumuti rusange. Igiciro cyinshi mugihugu kiri mu nzira y'amajyambere kiri hagati ya  0.01 na  0.04 kuri dose. Muri Reta zunzubumwe za Amerika, igura amadolari  0.05 kuri dose. Muri 2017, yari imiti ya 28 yandikiwe cyane muri Amerika, hamwe na barenga 24miriyoni.

 Reba 

Category:Translated from MDWiki