Nekrosis

Nekrosis (daripada Yunani purba: νέκρωσις "kematian, peringkat kematian, pembunuhan" daripada νεκρός "mati") ialah satu bentuk kecederaan sel yang menyebabkan kematian pramatang sel pada tisu hidup melalui autolisis.Proskuryakov, S. Y. a., Konoplyannikov, A. G. & Gabai, V. L. Necrosis: a specific form of programmed cell death? Experimental Cell Research 283, 1-16, doi:10.1016/s0014-4827(02)00027-7 (2003). Nekrosis disebabkan oleh faktor yang luaran kepada sel atau tisu, seperti jangkitan, toksin, atau trauma yang menyebabkan pencernaan tidak terkawal atur bagi komponen sel. Berlawanan pula, apoptosis ialah sebab teratur cara dan bersasar yang berlaku secara semula jadi bagi kematian sel. Sementara apoptosis kerap menyediakan kesan bermanfaat kepada organisma, nekrosis hampir selalu memudaratkan dan boleh membawa maut.Kasper D.L., Zaleznik D.F. (2001). Gas gangrene, antibiotic associated colitis, and other Clostridial infections. In Braunwald E., Kasper D.L. et.al (Eds). Harrisons’s principles of internal McGraw Hill, New York

Lihat juga
 Nekrosis avaskular
 Luka beku
 Gangren
 Radang fascia menekrosis
 Osteonekrosis rahang
 Nekrolisis epidermis toksik

Rujukan

Nota
1.	Proskuryakov, S. Y. a., Konoplyannikov, A. G. & Gabai, V. L. Necrosis: a specific form of programmed cell death? Experimental Cell Research 283, 1-16, doi:10.1016/s0014-4827(02)00027-7 (2003).

2.	Kasper D.L., Zaleznik D.F. (2001). Gas gangrene, antibiotic associated colitis, and other Clostridial infections. In Braunwald E., Kasper D.L. et al. (Eds). Harrisons’s principles of internal medicine 15th ed., pp. 922–927. McGraw Hill, New York

3.	Vinay K, Abul K. A., Nelson F, Jon A. (2010) Robbins & Cotran Pathologic Basis of Disease, 8th ed., pp. 12–41. Saunders Elsevier, Philadelphia

4.	Craft, J. et al. Understanding Pathophysiology. 1 edn,  (Mosby Elsevier, 2011).

5.	Kumar, V., Abbas, A. K., Fausto, N. & Aster, J. C. Robbins and Cotran Pathological Basis of Disease. 8 edn,  (Saunders Elseveir, 2010).

6.	McConnell, T. H. The Nature of Disease: Pathology for the Health Professional.  (Lippincott Williams & Wilkins, 2007).

7.	Stevens, A., Lowe, J. S. & Young, B. Wheater's Basic Histopathology: A Colour Atlas and Text. 4 edn,  (Churchill Livingstone, 2003).

8.	Nazarian, R. M., Van Cott, E. M., Zembowicz, A. & Duncan, L. M. Warfarin-induced skin necrosis. Journal of the American Academy of Dermatology 61, 325-332, doi:10.1016/j.jaad.2008.12.039 (2009).

9.	Raffray, M. & Gerald M, C. Apoptosis and necrosis in toxicology: A continuum or distinct modes of cell death? Pharmacology & Therapeutics 75, 153-177, doi:10.1016/s0163-7258(97)00037-5 (1997).

10.	Proskuryakov, S. Y. a., Konoplyannikov, A. G. & Gabai, V. L. Necrosis: a specific form of programmed cell death? Experimental Cell Research 283, 1-16, doi:10.1016/s0014-4827(02)00027-7 (2003).

11.	http://www.nature.com/cdd/journal/v16/n1/pdf/cdd2008150a.pdf 

13.	Robertson, J Burke, B Caceci, T Santo, A n.d, ‘Introductory pathology lab exercises’, dicapai pada 9 September 2012, <http://www.vetmed.vt.edu/education/Curriculum/VM8304/vet%20pathology/VETPATHINVET.htm >.

14.	Eum, H.-A., Cha, Y.-N. & Lee, S.-M. Necrosis and apoptosis: Sequence of liver damage following reperfusion after 60 min ischemia in rats. Biochem. Biophys. Res. Commun. 358, 500-505, doi:10.1016/j.bbrc.2007.04.153 (2007).

15.	Cooper, K. L. Skin and Wound Care. Drug Reaction, Skin Care, Skin Loss. Crit. Care Nurse 32, 52-59, doi:10.4037/ccn2012340 (2012).

16.	Chotenimitkhun, R. & Rojnuckarin, P. Systemic antivenom and skin necrosis after green pit viper bites. Clinical Toxicology (15563650) 46, 122-125, doi:10.1080/15563650701266826 (2008).

17.	Edinger, A. L. & Thompson, C. B. Death by design: apoptosis, necrosis and autophagy. Curr. Opin. Cell Biol. 16, 663-669, doi:10.1016/j.ceb.2004.09.011 (2004).

18.	Anu, S., Ernane, D. R. & Morris, D. K. Options for nonsurgical debridment of necrotic wounds. Advances in Skin & Wound Care 14, 96-96 (2001).

19.	Horobin, A. J., Shakesheff, K. M. & Pritchard, D. I. Maggots and wound healing: an investigation of the effects of secretions from Lucilia sericata larvae upon the migration of human dermal fibroblasts over a fibronectin-coated surface. Wound Repair. Regen. 13, 422-433, doi:10.1111/j.1067-1927.2005.130410.x (2005).

Pautan luar
 Life In The Fast Lane: toxicology Conundrum #018 

 Secondary necrosis of a neutrophil 

Kategori:Kematian
Kategori:Proses sel