CYP2C9

Cytochroma P450 CYP2C9  (Numerus EC: 1.14.13.48) est haemoproteinum et pars gregis cytochromatum P450. 

 Natura structuraque biochemica 
Cytochroma P450 CYP2C9 est et polypeptidum et haemoproteinum, quod ex 490 acidis aminicis (massa 55.628 Da) constitutum est. Intra cellulam enzymum hoc in ancoris membranae stat.

 Genetica 
Nomen geni cytochromatis est CYP2C9 locus cuius geneticus in chromosomate 10 humano locatus est (10q23.33). 

 Pharmaca ad CYP2C9 relata 
 Pharmaca relata ad CYP2C9Cozza KL, Armstrong SC (2001). The Cytochrome P450 System. Drug Interaction Principles for Medical Practice. Washington, DC: American Psychiatric PublishingPreskorn SH (1996). Clinical Pharmacology of Selective Serotonin Reuptake Inhibitors. 1st ed.: Professional Communications, Inc..|-
! Substrati !! InhibitoresInhibitor cum subtratorum effectibus fortioribus !! InductoresInductor cum subtratorum effectibus minoribus
|- style="vertical-align: top;"
|
 AINS (antinflammatoria nonsteroidalia)
 Celecoxibum
 Etoricoxibum
 Diclofenac
 Ibuprofenum
 Naproxenum
 Antidepressiva
 Amitriptylinum
 Fluoxetinum
 Inhibitor receptorii angiotensini II
 Candesartanum
 Irbesartanum
 Losartanum
 Sulphonylureae
 primae generationis
 Tolbutamidum
 secundae generationis
 Glipizidum
 Glibenclamidum
 Glimepiridum
 Glyburidum
 Tamoxifenum
 Fluvastatinum
 Ketaminum
 Torasemidum
 Cannabis
|| 
 Fluconazolum (forte)
 Acidum valproicum (forte)
 Amiodaronum
 Antidepressiva
 Sertralinum
 Statini
 Fluvastatinum
 Lovastatinum
||
 Rifampicinum (forte)
 Secobarbitalum''' (forte)
 Phenobarbitalum

 Notae 

 Nexus externi 
 Descriptio genetica CYP2C9: https://ghr.nlm.nih.gov/gene/CYP2C9#

2