Receptorium histamini

Receptoria histamini sunt receptoria neurotransmissoria et classis receptoriorum proteino G copulatorum cum histamino ligando endogenoClassificatio internationalis receptorum Histamini: Hill SJ, Ganellin CR, Timmerman H, Schwartz JC, Shankley NP, Young JM, Schunack W, Levi R, Haas HL (1997). Pharmacol. Rev. 49 (3): 253–78.

Adhuc quattuor typi receptoriorum histamini noti sunt.: 
 Receptorium histamini H1 - Contractiones ilei, vasodilatatio, pruritus, bronchoconstrictio. Antagonista H1 receptorii: Diphenhydraminum, Loratadinum, Cetirizinum, Fexofenadinum, Clemastinum 
 Receptorium histamini H2 - Stomachus: incrementum secretionis chymi. Antagonista H2 receptorii: Ranitidinum, Cimetidinum, Famotidinum, Nizatidinum
 Receptorium histamini H3 - deminutio concentrationis in cerebro Acetylcholini, Serotonini, Noradrenalini 
 Receptorium histamini H4 - Chemotaxis (mastocytus) 

 Histaminum 

In organismis histaminum est neurotransmissor, quae signa per nervos transmittit. Praeterea in allergia histaminum pars reactionis systematis immunitatis est.

 Notae 

Categoria:Systema histaminergicum (histaminum)
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