(+)-cis-2-アミノメチルシクロプロパンカルボン酸

(+)-cis-2-アミノメチルシクロプロパンカルボン酸((+)-cis-2-Aminomethylcyclopropane carboxylic acid、(+)-CAMP)は、GABAC亜類型のための選択的なGABAアゴニストであるDuke RK, Chebib M, Balcar VJ, Allan RD, Mewett KN, Johnston GA. (+)- and (-)-cis-2-aminomethylcyclopropanecarboxylic acids show opposite pharmacology at recombinant rho(1) and rho(2) GABA(C) receptors. Journal of Neurochemistry. 2000 Dec;75(6):2602-10. Carland JE, Moorhouse AJ, Barry PH, Johnston GA, Chebib M. Charged residues at the 2' position of human GABAC rho 1 receptors invert ion selectivity and influence open state probability. Journal of Biological Chemistry. 2004 Dec 24;279(52):54153-60. 。

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Category:アミノ酸