William McGinnis

William McGinnis masanin kimiyyar kwayoyin halitta ne na Amurka wanda farfesa ne a fannin ilmin halitta a Jami'ar California San Diego . A UC San Diego ya kuma yi aiki a matsayin Shugaban Sashen Ilimin Halitta daga Yuli 1998 zuwa Yuni 1999, a matsayin Mataimakin Dean na Sashen Kimiyya na Halitta tun daga Yuli 1, 1999 zuwa Yuni 2000, kuma a matsayin Mataimaki Dean na sabon Sashen Kimiya na Halittu daga Yuli 1, 2000 zuwa Fabrairu 1, 2001. An nada McGinnis a matsayin Dean na Divisional Biological Sciences a ranar 1 ga Yuli, 2013.

Ya sami Ph.D. daga UC Berkeley a 1982 kuma ya kasance Jane Coffin Childs postdoctoral fellow a Jami'ar Basel . Daga 1984 zuwa 1995, ya kasance a bangaren koyarwa na Jami'ar Yale. Ya sami lambar yabo ta Searle Scholar, lambar yabo ta Shugaban kasa Young Investigator, da kuma lambar yabo ta Dreyfuss Teacher / Scholar. An zabi McGinnis a Kwalejin Fasaha da Kimiyya ta Amurka a shekarar 2010, da kuma Kwalejin Kimiyya ta Kasa a shekarar 2019.

 Bincike 
McGinnis yana nazarin canje-canjen juyin halitta a cikin Abubuwan fassarar ta hanyar kallon Kwayoyin halittar Hox. Babban bincikensa ya kasance a cikin Drosophila,  yana kwatanta kwayoyin halittar Hox a cikin wannan nau'in tare da kwayoyin halittun Hox a wasu nau'o'in, don ganin an kiyaye su (an kiyaye su ba tare da lalacewa ba) yayin juyin halitta. Ya kuma yi nazarin yadda Hox transcription ke sarrafa morphogenesis, da kuma yadda canje-canje a cikin Hox sunadarai, cofactors, da DNA manufofi ke shafar morphology. Ɗaya daga cikin manufa na dogon lokaci na binciken a cikin dakin gwaje-gwaje shi ne fahimtar hulɗar kwayoyin da ke haifar da takamaiman aiki a cikin tsarin tsarin Hox.

McGinnis sananne ne saboda ganowar homeobox, tare da Michael S. Levine . Amma abin da ke da mahimmanci, don binciken cewa an samo kwayoyin halittar Hox (homeobox) a cikin dabbobi da dabbobi iri-iri, an kiyaye su, kuma an bayyana su a yankuna daban-daban na ƙwayoyin halittar jiki na ƙwayoyi, kuma cewa kwayoyin halittun Hox na dabbobi masu shayarwa na iya aiki a matsayin masu sarrafa ƙwayoyin halitta na baya-baya na ƙayyadaddun jiki, a cikin kwari da dabbobi masu shan ruwa. Wato, ayyukan kwayar halitta na Hox sun kasance iri ɗaya ne wajen sarrafa tsarin jikin jiki a cikin kwari da sauran dabbobi masu rikitarwa, kamar dabbobi masu shayarwa.

 Manazarta 

Rukuni:Rayayyun mutane