Gwajin Cibiyar Jama'a

Gwajin bincike na cibiyoyi da yawa shi ne gwajin asibiti wanda ya shafi cibiyoyin kiwon lafiya masu zaman kansu fiye da ɗaya a cikin yin rajista da bin mahalarta gwajin. A cikin gwaje-gwaje masu yawa cibiyoyin da suka halarci suna bin ka'idojin magani na yau da kullun kuma suna bin jagororin tattara bayanai iri ɗaya, kuma akwai cibiyar daidaitawa guda ɗaya da ke karɓar, sarrafawa da nazarin bayanan binciken.

 Fa'idodi 
Wani muhimmin fa'ida na gwaje-gwaje masu yawa shine cewa suna ba da izinin yin rajistar yawancin mahalarta da sauri, idan aka kwatanta da gwajin cibiyar guda ɗaya, yin amfani da tushen cibiyoyi da yawa. Wannan yana da mahimmanci lokacin da fa'idar da ake tsammani daga magani zai zama karami, ko kuma sakamakon da ake tsammami zai iya zama abin mamaki, yana sa girman samfurin ya zama dole. Sabili da haka, ana tsara nazarin kan matakan rigakafi da warkewa a matsayin gwaje-gwaje masu yawa. A cikin nazarin sabbin magunguna, gwaje-gwaje na Mataki na III, wanda ke kwatanta sabon magani da wanda aka kafa, yawanci masu yawa ne. Sabanin haka, gwaje-gwaje na Mataki na I, wanda ke gwada yiwuwar guba na magani, da gwaje-gaje na Mataka na II, wanda ke tabbatar da ingancin farko na maganin da aka gwada, yawanci gwaje-gwagwarmaya ce guda ɗaya, saboda suna buƙatar ƙananan mahalarta.

Fa'idodin gwaje-gwaje masu yawa sun haɗa da yiwuwar ƙarin samfurin mahalarta, daga wurare daban-daban da kuma ƙungiyoyin jama'a masu yawa, waɗanda aka bi da su daga likitoci na asali daban-daban, da kuma ikon kwatanta sakamakon tsakanin cibiyoyin, dukansu suna ƙara yawan binciken. A lokuta da yawa, inganci zai bambanta sosai tsakanin kungiyoyin jama'a tare da asali daban-daban na kwayoyin halitta, muhalli, da kabilanci ko al'adu ("halayen"); gwaje-gwaje masu yawa sun fi kyau wajen kimanta waɗannan abubuwan, ta hanyar ba da damar don ƙarin nazarin rukuni. Heterogeneity a cikin samfurin yana nufin cewa binciken zai zama mafi yawanci. A gefe guda, yawan binciken da ya fi dacewa yana buƙatar girman samfurin da ya fi girma don gano bambancin da aka ba shi.

 Manazarta 

 Haɗin waje 

 ClinicalTrials.gov daga US National Library of MedicineLaburaren Magunguna na Kasa
 Matsayin ICH GCP da dabarun daukar ma'aikata Horar da Ma'aikatan Sites na Asibiti a cikin Rashin Samun Ma'aikata na Marithea Goberville, Ph.D.
 Littattafan IBPA na 2005